摘要
在供应碘盐的碘缺乏病（ＩＤＤ）重病区，对育龄妇女孕前一次给予不同剂型和剂量的碘化油后尿碘动态观测表明：１．投药前１７．８％的观察对象尿碘不及１００μｇ／Ｌ；２．投药后尿碘排泄水平受服用剂量影响，不受剂型的影响；３．仅以尿碘为依据，口服０．２ｇ碘化油有效期不超过１年，口服０．１ｇ碘化油有效期仅为半年。据此建议，对育龄妇女实施强化补碘措施，一次投服碘化油剂量在０．２ｇ以上，每年投药１次，直至哺乳期满，才能达到预防临床型和亚临床型克汀病发生的目的。
Different forms and doses of iodinated oil were given to bearing-age women before pregnancy in sere IDD regions where iodinated salt was already supplied. The results of urinary iodine showed 1. Be fore giving iodinated oil, urinary iodine levels in subjicts of 17. 8%, was lower than 100μg/L; 2. Urinary iodine was affected by drug dose but not drug form after giving iodinated oil; 3. Based on urinary iodine level if taking 0. 2g iodinated oil orally, the duration of efficacy was not longer than one year, and if 0. 1g ,only half a year. Therefore, we suggest that the dosage of iodinated oil should be over 0. 2g, taking once a year. Under such program, the purpose of preventing clinical and subclinical cretinism can be served.
出处
《中国地方病学杂志》
CAS
CSCD
1995年第4期209-211,共3页
Chinese Jouranl of Endemiology
关键词
碘缺乏病
育龄妇女
碘化油
尿碘
IDD
Bearing-aged women
Iodinated oil
Urinary iodine
