摘要
】为了解高碘对机体脑发育及代谢的影响，本实验用高碘水喂养小鼠复制出高碘甲状腺肿动物模型。结果发现，用高碘水喂养小鼠２１０天后，高碘组小鼠体重减轻，甲状腺重量明显增加，血清ＦＴ３及ＦＴ４水平均显著高于适碘组。两组比较脑重、脑ＤＮＡ、蛋白质含量均无显著差异。揭示高碘不影响脑发育但可使代谢率增加。
In order to study the effect of iodine excess on brain development and metabolism.We replicated the model of iodine excess thyroid goiter with KunMing male mice.At the end of 210 days,the mice were killed.Compared with suitable iodine group,the thyroid weight,the level of serum FT 3 and FT 4 increased apparently,the body weight decreased.There was no difference in content of drain DNA,protein and the brain weight.The result showed that iodine excess did not affect brain development,but increased the rate of metabolism.
出处
《河北省科学院学报》
CAS
1997年第3期46-48,共3页
Journal of The Hebei Academy of Sciences
关键词
高碘
碘
甲状腺肿
脑发育
机体代谢
Iodine excess,Goiter,Free triiodothyronine(FT 3),Free thyroxin(FT 4)
