摘要
采用Low Shear-30流变测定仪,改变人血红细胞压积(HCT),血浆浓度和正弦振荡剪切流频率,观察血液粘弹特性的变化。建立了经验方程,以表示HCT与粘性分量(η′),弹性分量(η″)的关系。
<ABSTRACT>
Whole blood of human being exhibits visco-elastic behavior at low
shear rate. The visco-elasticity of human blood can be measured with
sinusoidal oscillatory shear flow. Using Low Shear-30 Sinus Rheometer,
we studied effects of hematocrit, plasma concentration and frequency
of sinusoidal oscillatory shehar flow on visco-elasticity of human blood.
According to Thurston, complex viscosity (n ) of whole blood of human
being consists of viscous component(n' ) and elastic component (n ),
n = n-in. The results demonstrated that n' and n increased exponent-
ially with increasing HCT. This communication developed empirical equ-
ations to express relationship between HCT and n, n, increase of
HCT affecting n more obviously than n. When the plasma was diluted
from 100% to 80, 60, 40, 20% with HCT controlled at 45.0±0.5%, the
mean values of n' were found decreased linearly with plasma concentration
being decreased more obviously than n'. When frequency of sinusoidal shear
flow was increased with HCT controlled at 45.0±0. 5%, n' and n were
decreased exponentially at the same rate with inverse of frequency. The
shear elastic modu1us G' inereased and relaxation time λredued exponenti -
ally with inverse of frequency as the frequency of shear flow was iner-
eased. Empirical equations were established respectively, expressing re -
lationship between frequency and,n, n, G', λ. The results provided
theoretical basis for application of viscoelastic parameters of blood in
clinical medicine.
出处
《中国生物医学工程学报》
EI
CAS
CSCD
北大核心
1989年第2期96-101,共6页
Chinese Journal of Biomedical Engineering
基金
国家自然科学基金资助项目
关键词
人
血
粘弹性
Flow of Fluids
Mathematical Models
Rheology
Rheometers
Viscoelasticity
Research
