摘要
本文用Low Shear 30流变仪测定了350例健康受试者(男178名,女172名)的红细胞压积(HCF)、自然状态下的血液粘弹性参数和其他血液流变参数。结果证明男子组血液的粘性分量(η′)、弹性分量(η″)、剪切弹性模量(G′)、在0.512秒^(-1)和51.2秒^(-1)下全血表观粘度(η0.512、η51.2),以及HCF的数值明显高于女子组。女子组血液的释氧系数(O.D.)比男子组高,但男、女两组的纤维蛋白原和血浆粘度(ηp)无明显差异。分别将男、女两组按年龄分成5个小组,探讨年龄差别对粘弹性参数和其他流变参数的影响。纤维蛋白原和ηp随年龄增长而增高,HCT、η0.512、η51.2在男子第Ⅴ组比Ⅰ～Ⅳ组明显降低,在女子第Ⅰ组比第Ⅴ组明显增高。O.D.在男女的两组随年龄增长而几乎平行下降;η′在男、女第Ⅲ、Ⅳ组均有高峰值,而η″和G′在男子第Ⅲ组和女子第Ⅰ组明显高于其他组。本文的结果证明性别和年龄对血液的粘弹特性和其他流变参数均有明确的影响。
With Low Shear 30 Rheometer, viscoelastic properties and related hemorheological parameters of whole blood from 350 healthy subjects (178 males, 172 females) were measured in its natural form at the native hematocrit(HCT). The results demonstrated that viscous component (η′), elastic component (η″), shear elastic modulus (G′) of whole blood, apparent viscosity of whole blood at shear rate 0.512 s^(-1)(η 0.512) and 51.2 s^(-1) (η 51.2) and HCT in the male subjects were statistically higher than those in the females. The females had higher oxygen delivery coefficient (O.D.) than the male group, but no significant differences existed in fibrinogen and plasma viscosity (η_p) between both sexes. Both male and female subjects were divided respectively into five subgroups in term of age in order to oberve the effects of age on viscoelastic and other rheological parameters of blood. Fibrinogen and η_p increased with aging. The values of hemoglobin (Hb), HCT, η 0.512 and η 51.2 in male subgroup V were obviously lower than those in male subgroups Ⅰ-Ⅳ and the parameters in female subgroup I were significantly higher than subgroup V. O. D. in both sexes decreased almost side by side with aging: η′ had the peak values in men and women subgroups Ⅲ, Ⅳ but η″ and G′ in men subgroup Ⅲ and women subgroup I were higher than other subgroups. The result ssuggested that sex and age had definite effect on the viscoelastic and related rheological parameters of whole blood.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
1990年第1期1-6,共6页
Journal of Biomedical Engineering
基金
国家自然科学基金
关键词
血液粘弹性
血液流变学
红细胞压积
Viscoelastic properties of blood
Hemorheology
Healthy subjects
Hematocrit.
