摘要
本文报告经病理证实颅内生殖细胞瘤３２例，其中松果体区１０例，鞍上１１例，基底节区６例，其它５例。年龄１０～５８岁，２０岁以下２２例。病程１月至７年，平均２．５年。主要临床表现为头痛、尿崩、偏瘫。手术切除肿瘤２９例，立体定向活检３例。术后症状改善２４例，不变５例，加重３例。作者认为颅内生殖细胞瘤诊断主要依据临床表现、肿瘤标记物（ＰＬＡＰ等）检测及ＣＴ扫描；治疗为手术加放疗。
hirty-two cases of pathologically proven intracranial germinoma are reported.Among them,10 tumors originated in the pineal area,11 in the supersellar region,6in the basal ganglia and 5 in other areas.The patients were age from 10 to 58 years.The symptoms lasted from l month to 7 years(mean,2.5 years).Headache,diabetesInsipidus and hemiparesis were the main clinical presentations.Tumor resection werecarried out in 29 cases and stereotactic biopsy in 3 cases.The postoperative clinicalstatus were improved in 24 cases,unchanged in 5 and worsen in 3.It is suggestedthat the diagnosis of intracranial germinomas may be based on the clinical features,tumor markers and CT scans,and the treatment may include surgery and irradation.
出处
《上海医学》
CAS
CSCD
北大核心
1995年第4期192-195,共4页
Shanghai Medical Journal
