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鼻咽癌患者NK、mIL-2R、sIL-2R及TNF的初步观察 被引量:3

Preliminary study of NK,mIL-2R,sIL-2R and TNF of Nasopharyn-geal Carcinoma Patients
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摘要 本文对30例鼻咽癌患者的四项免疫学指标进行了检测,发现mIL-2R表达减少,sIL-2R和TNF水平升高,NK活性与正常对照无显著差异,提示患者免疫功能抑制。上述指标与鼻咽癌病期的关系有待进一步研究。 our immunological parameters were investigated for 30 nasopharyngeal carcinoma patients.Itwas found that the expression of mIL-2R decressed,serum levels of sIL-2R and TNF elevated compared withnormal control group The difference of NK activity between NPC patients and normal control was not signifi-cant.It indicated that the immunological function of nasopharyngeal carcinoma patients was seriously sup-pressed.The correlation of the four immunological parameters with clinical stage of patients needs furtherstudies.
出处 《免疫学杂志》 CAS CSCD 北大核心 1995年第1期37-39,共3页 Immunological Journal
关键词 鼻咽肿瘤 白细胞介素2 肿瘤坏死因子 Nasopharyngeal carcinoma,mIL-2R,sIL-2R,NK,TNF
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  • 1Lin C C,Chest,1987年,92卷,1022页
  • 2G. Stuber,F. Vánky,E. Pócsik,M. Benczúr,E. Klein. Expression of interleukin-2 receptor on blood lymphocytes stimulated with allogeneic lymphocytes or autologous tumor cells[J] 1990,Cancer Immunology Immunotherapy(2):76~80
  • 3Stephan D. Voss,Jacquelyn A. Hank,Catherine A. Nobis,Paul Fisch,Jeff A. Sosman,Paul M. Sondel. Serum levels of the low-affinity interleukin-2 receptor molecule (TAC) during IL-2 therapy reflect systemic lymphoid mass activation[J] 1989,Cancer Immunology Immunotherapy(4):261~269
  • 4富宁,王莉,杨贵贞.单克隆与多克隆双抗体夹心法测定血清可溶性IL-2受体[J].中国免疫学杂志,1991,7(5):278-281. 被引量:273

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