摘要
激素依赖型乳腺癌患者术后服用三苯氧胺(TAM)可以改善预后的效果已被人们承认,TAM 对人体机能包括免功能影响的研究也在不断深入。作者对收治的12例乳腺癌术后患者进行TAM 眼药前后 NK 活性及 T 细胞数量变化的检测,与对照组比较,发现三苯氧胺对乳腺癌术后化疗患者的 T 细胞数量减少有帮助恢复的作用,同时对 NK 细胞活性也有改善作用。
It has been demonstrated that administration ot TAM can improve the prognosis of patients with breast carcinoma that shows positive hormonereceptor.There were reports that TAM may also favorably affect the im- mune function of breast cancer patients in literature.In this research,the activity of natural killer cell and the number of T-lymphocytes were analysized in twelve pa- tients who had received TAM for one month after mas- tectomy for breast carcinoma.The results showed that the activity of NK cell can be improved and the diminu- tion of T-lymphocyte population caused by chemothera- py might be recovered by the administration of TAM. This observation supports the hypothesis that TAM may be applied to in a larger scale.
出处
《普外临床》
CSCD
1995年第6期367-369,共3页
