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子宫内膜异位症患者性周期β-内啡肽变化及中药内异方对其的影响 被引量:9

Effect of Nei-Yi Recipe on Plasma β-endorphin Levels during Menstrual Cycle in Women with Endometriosis
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摘要 本研究检测了子宫内膜异位症(内异症)患者治疗前后及健康人卵泡期、黄体期外周血。β-内啡肽(β-EP)水平。结果提示:(1)内异症患者痛经程度与黄体期β-内啡肽水平高低有关。(2)中药内异方通过提高内异症患者β-EP水平,从而缓解痛经、盆腔痛,并调节内异症患者的免疫功能。 In order to investigate the mechanism of Nei-Yi Recipe(NYR)in treatment of endometriosis,we observe the changes of plasma β-endorphin concentrations in women with endometriosis treated by NYR. It was found that in luteal phase β-endorphin concentrations in plasma were significantly reduced in moderate and severe dysmenorrhea groups compared with mild and control groups.Moreover,β-endorphin level in severe dysmenorrhea group was lower in the luteal phase than that in the follicular phase,and it was lower in patients with pelvic pain than that without pelvic pain.In normal women,the contents of β-endorphin in plasma were not changed during menstrual cycle.It was also found that plasma β-endorphin levels were significantly increased in luteal phase and follicular phase after treatment by NYR.The therapeutical mechanism of NYR on dysmenorrhea and pelvic pain and enhancement of immune function might be mediated by increase of plasma β-endorphin levels.
出处 《中国中西医结合杂志》 CSCD 北大核心 1995年第1期6-8,共3页 Chinese Journal of Integrated Traditional and Western Medicine
关键词 子宫内膜异位症 黄体期 卵泡期 中药内异方 endometriosis follicular phase luteal phase β-endorphin Nei-Yi Recipe
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