摘要
目的:评价MR化学位移成像序列对脊柱压缩骨折病因的鉴别诊断价值。材料和方法:53例(共97个椎体)脊柱椎体压缩行MRI平扫和化学位移序列检查。其中病理性骨折31例(61个椎体,包括转移性肿瘤26例、骨髓瘤1例、结核4例);单纯性骨折22例36个椎体,包括单纯外伤所致15例,骨质疏松7例。病理性骨折者行CT导引下经皮骨穿刺检查或手术病理证实,部分临床证实;外伤或骨质疏松所致椎体压缩骨折均符合临床、实验室检查及MRI表现,部分随访证实。结果:快速梯度回波反相位序列上,41个病理性压缩椎体为高信号,20个椎体表现基本为等或稍低信号;而25个单纯性压缩椎体在快速梯度回波反相位序列上则表现为低信号,11个椎体表现为等或稍高信号,卡方检验P>0.05。在快速梯度回波正相位序列上,压缩椎体基本上均为低信号。脊柱病理性骨折的反相位/正相位信号比是1.27+/-0.35,而良性压缩骨折反相位/正相位信号比是0.83+/-0.28,经统计分析P<0.05。结论:化学位移序列在鉴别脊柱单纯性和病理性压缩骨折方面有较高的应用价值。
To evaluate the effectiveness of value of MR chemical shift imaging for differentiating between benign and pathologic vertebral compression fracture.Materials and Methods:53vertebral fracture(97vertebra)patients,including31pathologic compression fractures(61vertebra including26metastasis,1myeloma,4tuberculosis)and22benign fracture(36vertebra including15traumatic and7osteoporotic fractures),were examined with conventional MR(T 1 W,T 2 W and STIR)and MR chemical shift imaging.Pathological fracture was proven by biopsy or surgery and benign compression fracture were proven by clinical manifestation,MRI and follow-up.Results:Compared with near normal vertebral bone mar-row,25acute benign vertebral bodies revealed hypointense while11acute benign vertebral bodies dis-played iso or slightly hyperintense on opposed image,41pathological vertebral ones were hyperintense and20pathological vertebral bodies revealed iso or hypointense on opposed image,P>0.05.On in-phase image all benign and pathological bodies were hypointense.The OP/IP signal ratio of the patho-logical fracture was1.27+/-0.35,while The OP/IP signal ratio of benign fracture was0.83+/-0.28,P<0.05.Conclusion:Chemical shift technique is helpful to distinguish benign and pathologic vertebral compression fracture.
出处
《中国医学计算机成像杂志》
CSCD
2005年第3期194-197,共4页
Chinese Computed Medical Imaging
基金
上海市医学科技发展基金资助项目(编号:034052)
