摘要
本实验应用黄曲霉毒素B_1致大鼠肝癌模型,动态观察养阴方和清解方在与黄曲霉毒素B_1同时使用及明显癌前病变出现后使用时肝内Mn—SOD的变化。结果表明,两中药方对黄曲霉毒素B_1致大鼠肝癌作用过程中所引起的肝内Mn—SOD下降有一定防止或阻断作用。提示两中药方对肝内Mn—SOD活力有一定的保护作用,进而增强了其清除超氧自由基的能力,降低了肝癌的发生率。
This experimental research observed the changes of Mn -SOD in rat' s liver during cancera-tion.when the nurishing-yin decoction- clearing decoction and aflatoxinBi were applied together. The results showed that the chinese herbs decoctions could prevent and stop the decreasing of Mn - SOD in rat' s Liver during canceration which induced by aflatoxin B! , this suggested that these two decoctions could protect the activity of Mn -SOD in liver, then strengthened the ability to clear superoxide free radical,decreased the morbidity of liver cancer.
出处
《中国中医药科技》
CAS
1994年第3期26-27,共2页
Chinese Journal of Traditional Medical Science and Technology
