摘要
本文报告经额入路垂体腺瘤切除４２１例术后经再次手术及病理确诊复发２３例，复发与年龄有关。肿瘤切除是否完整是复发的关键因素。肿瘤的侵袭性亦是术后复发的重要原因，本组肿瘤多属巨大型，病理发现有侵袭性，再次手术有恶化倾向，特别是向包膜及周围组织浸润，大体亦有侵袭性。本组１例Ｎｅｌｓｏｎ氏综合征，提示复发的内分泌因素。再手术发现局部粘连，解剖关系严重紊乱；术后视觉障碍好转率明显下降；死亡率增加，认为再手术选择应慎重。
Four hundred and twenty one cases oftransfrontal removal of pituitary adenomas were pre-sented. of these 23 had recurrence of tumor whichwas confirmed by reoperation and histopathological ex-amination. The rate of recurrence decreasd while thepatients’ age increased. Incomplete removal of the tu-mor tissue was one of the most imporiant causes of re-currence. Invasiveness was another important cause.Most of the tumors in this series were large and hadpathologically proven invasiveness. At the reopera-tions,there were evidences of worse invasiveness,es-pecially the infiltration of adenomas into the capsulesand adjacent structrues.There was a case of Nelson’ssyndrome,suggesting the endocrine cau ses of recur-rence. Apparent adhesion and topograp hic disorderswere found during reoperation,improvement of visualimpa irment decreased obviously,and the mortalityrate increased; therefore,the reoperations should bedecided with great deliberation.
出处
《华西医科大学学报》
CSCD
1994年第1期83-86,共4页
Journal of West China University of Medical Sciences
关键词
腺瘤
复发
外科手术
垂体肿瘤
Pituitary adenoma Recurrence Reoperation
