摘要
用１，２，５，６－二丙酮甘露醇与ＬｉＡｌＨ_４及手性一元醇在室温下形成的络合物对苯乙酮和苯丙酮在不同温度下进行不对称还原，得到光学活性醇，旋光产率在６．６～４４．４％之间。
Lithium aluminum hydride complexes prepared from 1,2,5,6-diisopropyli-denemannitol and chiral alcohol such as 1R,2S,5R(-)-menthol or S(+)-3-methyl-2-butanol areused to reduce acetdphenone or pro piophenone to yield corresponding chiral alcohol.Gas chrometogra-phy quantifying analysis showed the optical yield of this asymmetric reduction fall between 6.6～44. 4%.
出处
《合成化学》
CAS
CSCD
1994年第4期356-360,共5页
Chinese Journal of Synthetic Chemistry
基金
国家教委国内访问学者基金资助项目
关键词
手性醇
改性
氢化铝锂
芳香酮
不对称还原
Modification,Cliral alcohol,Asymmetric reduction,Optical activity diastereoiso-mer, Aryl ketone.
