摘要
在乌拉坦麻醉、切断双侧颈迷走神经的大鼠，观察到：电刺激颈迷走神经中枢端，在“迷走加压反应”之前常出现初始短暂的加压反应；间脑和中脑之间横断脑干不能衰减该反应，但双侧蓝斑（ＬＣ）内注射普鲁卡因或双侧延髓头端腹外侧区（ＲＶＬ）内注射阿托品以及酚妥拉明（ｉ．ｖ．）均能使该反应减小，而心得安（ｉ．ｖ。）则否。以上结果提示：该反应之机理不同于“迷走加压反应”，主要系通过ＬＣ－ＲＶＬ交感缩血管系统实现。
n urethane-anesthetized and bilaterally vagotomized rats、an initial short-term pressor response wasevoked before the appearence of the vagus-pressor response (the second pressor response)by stimula-ting the central end of the cervical vagus It could not be attenuated by transection of brain between diencephalon and mesencephalon bui injection of procaine into locus coeruleus (LC)or atropine into rostral ventrolateral medulla(RVL),and phentolamine(iv)all reduced it(only piopranololi.v.)did not)The results suggest that the initial pressor response(different from the vagus-pressor respo-nse)is mainly mediated by LC-RVL sympathoexcitatory system。
出处
《北京医科大学学报》
CSCD
1994年第1期13-16,共4页
Journal of Peking University(Health Sciences)
关键词
迷走神经
加压反应
蓝斑
室旁核
Vagal afferent:Pressor response
Locus coeruleus
Rostral ventrolateral medulla
