摘要
本文报道采用胃液多胺检测与胃镜活检普查相对照的方法，检测食管癌、胃癌高发区不同人群的胃液多胺水平。证实胃液多胺水平与食管或胃组织细胞的癌变程度有明显的平行关系，食管或胃上皮细胞受环境中有害物质长期刺激发生上皮细胞单纯增生时，胃液多胺含量升高２７．０８￣９６．７７％。阳性率３６．３６～５５％；进而发展为不典型增生时，多胺含量明显增加，升高８５．１９￣１９８．６９％阳性率６６．６７￣９０．９０％，癌变时胃液多胺含量升高４倍以上，阳性率均达１００％．表明胃液多胺检测用以筛检潜在的无症状食管癌，胃癌和癌前期病人，是一种简便可行，灵敏准确的方法。
This paper reports the determination of the polyamines of the gastric ju-ice combined with gastroscopy to generally screen different population groups living in the high-incidence areas of esophageal cancer and gastric cancer.These results show that the levelsof the polyamines of the gastric juice are closely correlated to the degree of carcinogenesis.When the epithlia of esophagus or stomach had a simple proliferation as a result of sti-mulation by the harmful substances of envitonment, such polyamimes could have a 27.08-96.77% rise with a positive rate of 36.36-55%.When atypical proliferation,85.19-198.69%(positive rate 66.67一90.90% ),When canceration,4 times with a positive rate of l00%。Thesere sults suggest that such determination can be used to screen latent symptomless patients withesophagral cancer and gastric cancer as well as precancerous lesions.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1994年第1期18-21,共4页
Chinese Journal of Cancer
关键词
食管
胃
多胺
检测
癌前状态
Esophagus Stomach Polyamine Detemine Detemimation
