摘要
本文报道59例食管癌患者尿多胺的含量分析结果,尿多胺含量的正常人明显增高,比正常均值增高的倍数各为:腐胺1.851倍,精脒2.302倍,精胺4.347倍,本组患者一项尿多胺增高者占总例数的89.83％,两项尿多胺增高者占总例数的84.75％。另外,在滤纸电泳图谱的腐胺和精脒色带之间又发现一分离清晰的新色带,在本组患者尿中亦见增多,为正常均值的2.655倍,增高的出现率为67.80％,曾对21例经手术和2例经化疗的患者进行复查,其各种尿多胺均于治疗后下降,表明屎多胺含量分析可作为食管癌患者辅助诊断和估计疗效的参考。
The amount of urinary polyamines of 59 patients with esophageal cancer was determined . The urinary polyamines in these patients were significantly higher than those in normal subjects. The putrescine. spermidine and sperm ine have been rised for 1.851 times, 2.302 times and 4.347 times higher than those in mormal subjects, of the three polyamines (putrescine, spermidine and spermine), a rise in one polyamine was seen in 89.83% of the patients, while the rise in two polyamines was seen in 84.75% of them. Between the putrescine and spermidine in the electrophoregram a histamine-like substance was detected, whose value was also high, being 2.655 times highger than the hormal value and having a 67.80% of positive rate of elevation. Patients' urinary polyamines were reduced as shown by iepeated assay bone in 21 cases post-operatively and in 2 cases after chemotherapy, the assay of urinary polyamines may be an auxiliary method useful in the diagnosis and prognosis of esophageal cancer.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1989年第3期184-186,共3页
Chinese Journal of Cancer
