摘要
本文观察了家犬油酸性急性肺损伤时红细胞的聚集性及相关指标。结果发现,红细胞聚集指数、红细胞压积、血浆镁显著增加,纤维蛋白(原)降解产物浓度显著升高;而纤维蛋白原、血浆钙和红细胞内镁明显减少。注射油酸后红细胞在自身血浆中的电泳时间明显延长,而在PBS中的电泳时间在360min时才显著延长。逐步回归分析提示,对红细胞聚集影响最大的因素是红细胞压积、红细胞内镁和红细胞表面电荷的变化。
Erythrocyte aggregation and related parameters were observed in this study.
Erythrocyte aggregation index, hematocrit and fibrin fibrinogen degradation products in-
creased significantly at 5 minutes after oleic acid injection. Erythrocyte electrophoretic time
in native plasma delayed obviously at 5 minutes after oleic acid injection, whereas that in
PBS altered very little. The concentration of plasma calcium and erythrocyte intracellular
magnesium decreased at 5 minutes, while plasma magnesium increased. The stepwise reg-
ression analysis suggested that during lung injury the parameters that have greatest effect on
erythrocyte aggregation were the change of hematocrit, erythrocyte intracellular magnesium
and negative charge of erythrocyte surface.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1993年第3期383-386,共4页
Chinese Journal of Pathophysiology
关键词
肺
油酸类
红细胞聚集
血液流变学
Lung
Oleic acids
Erythrocyte aggregation
Magnesium
Fibrin fibrinogen degradation products
