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膀胱癌患者血清内皮生长因子水平检测及临床意义

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摘要 目的 :检测膀胱癌患者血清血管内皮生长因子 (VEGF)的水平变化 ,探讨其与肿瘤的分级、分期的关系。方法 :采用 EL ISA法检测 4 8例膀胱癌患者 ,2 0例前列腺增生症患者和 30例正常对照组血清 VEGF水平。结果 :膀胱癌患者血清 VEGF的水平明显高于前列腺增生症组和诊断对照组。膀胱癌患者 VEGF的水平与肿瘤的分级、分期有关 ,其中局部浸润性癌显著高于浅表性癌 (P<0 .0 1) ;远处转移组显著高于局部浸润组 (P<0 .0 1)。G3级患者 VEGF水平均显著高于 G1 级和 G2 级 (P<0 .0 1)。结论 :膀胱癌患者血清中 VEGF水平显著升高 ,并与肿瘤的分级、分期及远处转移有关。
作者 朱鸿彬 李开运 陈球 尹永华 蔡凌
机构地区 深圳市沙井人民医院
出处 《临床医药实践》 2005年第2期95-97,共3页 Proceeding of Clinical Medicine
关键词 膀胱肿瘤 血管内皮生长因子 检测 临床意义
分类号 R737.14 [医药卫生—肿瘤]
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参考文献10

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二级参考文献38

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临床医药实践
2005年 第2期

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