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腔隙性脑梗死患者血压变化与预后的关系分析 被引量:1

Relationship between the changes of blood pressure and outcome in patients with lacunar infarct
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摘要 目的 探讨腔隙性脑梗死患者 2 4小时血压变化与预后的关系。方法 对 91例腔隙性脑梗死患者平均随访 3年 ,按不同预后分为三组 ,A组 4 1例 ,随访期间无再发生脑血管病和痴呆表现 ;B组 2 3例 ,有痴呆和静止性损害表现 ,包括腔隙性和弥漫性脑白质损害 ;C组 2 7例 ,有进展性脑梗死表现。另设 2 0例为对照组 (健康体检正常者 )。四组每年均进行一次头颅 MRI检查和血压监测。结果 A组 2 4小时、白天收缩压 ,2 4小时、白天及夜间舒张压均明显高于首次 ;B组明显低于首次 ;C组 2 4小时和白天收缩压均低于首次 ;对照组血压无明显变化。结论 腔隙性脑梗死预后良好者血压趋于升高 ,进展性梗死和痴呆者血压降低。 Objective To investigate blood pressure(BP) changes throughout a 24-hour period in lacunar infarct patients with different outcomes.Methods Twenty control subjects and 91 patients with lacunar infarct were followed up 3 years,and were divided into three groups according to their outcomes:group A,41 patients with a fair outcome without any cerebravascular attack or dementia;group B,23 patients with silent lesions and dementia,which included lacunar and diffuse white lesions;group C,27 patients who developed symptomatic infarct.Results In group A,the second measurement were significantly higher than the first for 24-hour systolic BP,daytime BP,24-hour diastolic BP,daytime diastolic BP,nighttime diastolic BP.In group B,the second measurement were significantly lower than the first for 24-hour systolic BP,daytime BP,24-hour diastolic BP and daytime diastolic BP.In group C,the second measurement were significantly lower than the first for 24-hour systolic BP and daytime BP.Conclusion BP tends to elevate in patients with a fair outcome.In contrast,BP tends to decrease in those who developed dementia and symptomatic infarct.
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出处 《山东医药》 CAS 北大核心 2005年第1期8-9,共2页 Shandong Medical Journal
关键词 腔隙性脑梗死 预后 血压变化 首次 患者 痴呆 对照组 关系分析 表现 平均 Lacunar infarct Systolic blood pressure Diastolic blood pressure Outcome
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  • 1Yasumasa Y,Akiguchi I,Oiwa K,et al. Adverse effect of nighttime blood pressure on the outcome of lacunar infarct patients. Stroke,1998,29(3) :570~576.
  • 2Makino Y,Kawano Y,Minami J,et al. Risk of stroke in relation to the level of blood pressure and other risk factors in treated hypertensive patients. Stroke, 2003,31 (1): 48~ 52.
  • 3Yasumasa Y, Ichiro A, Kaiyo O, et al. Twenty-four-hour blood pressure changes in the course of lacunar disease. Cerebrovascular Disease,2001,11(1):100~106.

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