摘要
目的 :研究c -fos在胃癌及淋巴结转移癌中的表达。方法 :应用兔抗人c -fos多克隆抗体 ,SP免疫组织化方法检测 76例胃癌及淋巴结转移癌组织。结果 :c -fos在胃癌及淋巴结转移癌的阳性率分别为 32 .6 %、6 3.3%。c -fos在淋巴结转移癌的表达率高于胃癌 (P <0 .0 5 )。结论 :c -fos在淋巴结癌的表达率高于胃癌 ,此现象说明 ,c-fos和癌的转移有密切的关系。
Objective: To study c-fos expression in gastic cancer and chinical lymph node metastasis.Methods: SP (Immunohistochemistry) staining was used to examine specimen of 76 cases with gastric cancer and lymph node metastasis cancer.Results: The positive rate of c-fos was 32.3% in gastric cancer(15/46) and 63.3% in lymph node metastasis cancer(19/30) respectively .The positive staining rate of c-fos in lymph node metastasis was higher than that of the gastric cancer(P<0.05).Conclusion: The c-fos is higher-expressed in lymph node metastasis than in gastric cancer. The result might Might illustrate that it has relation with the metastasis of the cancer.
出处
《河北北方学院学报（医学版）》
2004年第5期44-45,共2页
Journal of Hebei North University:Medical Edition
