摘要
用组化和细胞化学方法观察大鼠肝脏缺血不同时间后再灌注对琥珀酸脱氢酶(SDH)活性的影响,同时观察氯丙嗪的保护作用.结果发现,只有在长时间肝缺血,达到不可逆性损伤后再灌注的条件下,才可引起此酶活性降低,氯丙嗪对这种异常改变有明显的保护作用.
By histochemical and cytochemical means,we observed the effects of reperfusion on succinic dehydrogenase (SDH) activity at different times after hepatic ischemia.And in the meantime we observed the protective effect of chlorpromazine.The results showed that only reperfusion after long periods of hepatic ischemia (irreversible injury),caused the decrease in SDH activity,and that chlorpromazine had a profound protective effect against the ischemia-reperfusion injury to the rat liver.
出处
《解剖学杂志》
CAS
CSCD
北大核心
1993年第1期5-8,共4页
Chinese Journal of Anatomy
