摘要
应用 AgNOR 染色技术对32例泌尿系移行上皮及其肿瘤组织细胞核内 AgNOR 的定量研究表明,正常移行上皮与移行上皮乳头状瘤之间 AgNOR 差异无显著性(P>0.05),而移行上皮乳头状瘤、不同恶性程度的移行上皮癌各组间 AgNOR 比较,差异均有显著性(0.01<P<0.05)。瘤细胞中,AgNOR 的形态、数量及分布与肿瘤的分化程度相关。观察中注意到各组之间 AgNOR 数量上有部分重叠病例,并进行了讨论。因此,我们认为组织学观察结合 AgNOR 的测定可能对癌瘤的早期发现、早期诊断有所帮助。
Augyrophil technigue for nucleolar organizer regions(AgNOR)was used to quantitatively inves tigate the changes of nuclear AgNOR in the resected transitional epithelium and the tumor specimens of 32 eases.The results showed that there was no significant difference of the number of the AgNOR be- tween the nomal transitional epithelium and transitional epithelium papilloma (P>0.05),but there was significant difference between transitional epithelium papillona and transitional epithelium carcino- ma of different malignant grades(0.01<P<0.05).The shape,number and distribution of nuclear AgNOR was associated with the differentiation of tumors.It was found that there were some overlap cases in the numbers of AgNOR between each group.We discussed this condition.Therefore.we con- clude that histological observation combined with determination of the number of AgNOR may be help- ful in the early detection and diagnosis of the carcinoma.
出处
《河南肿瘤学杂志》
1993年第1期21-23,共3页
Henan Journal of Oncology
