摘要
目的 研究膀胱移行细胞癌行膀胱全切术后尿道再发肿瘤的原因及处理方法 ,进而提出预防及治疗措施 ,以降低尿道再发肿瘤的可能性。 方法 回顾分析 1978~ 1998年膀胱全切后尿道再发肿瘤 19例。 结果 尿道再发肿瘤占 9% ,均为男性。 18例发生于后尿道 ,1例发生于前尿道 ,主要症状为尿道溢血。 结论 再发原因除移行上皮肿瘤的多中心发生因素外 ,膀胱肿瘤已侵及前列腺及前列腺尿道是主要原因。“膀胱全切除”范围不够 ,残留前列腺及前列腺尿道以及膀胱切除时对肿瘤的挤压也是不容忽视的原因。少数病例也可经血行转移至前尿道。
Objectives To study the cause and treatment of urethral recurrence after total cystectomy and to find out prophylactic measures. Methods 19 patients with urethral relapse after radical cystectomy were analyzed retrospectively. Results The patients were male, accounting for 9% of the reearrent cases. The posterior urethra was involved in 18 patients and the anterior urethra was involved in 1. Their prognosis was poor. Conclusions The greatest risk factor for recurrence is tumor involvement of the prostate or the prostate urethra except for the multicentric nature of TCC. Other factors such as the retained prostate or prostate urethra because of improper radical cystectomy, and plant metastasis due to rough operation should not be neglected. A few of cases may be due to hematogenous metastasis. Total urethrectomy is recommended other than posterior urethrectomy.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2001年第3期215-216,共2页
Chinese Journal of Surgery