摘要
目的探讨CO2激光结合自体表皮移植治疗白癜风的临床疗效。方法对1605例白癜风患者进行自体表皮移植治疗,共植皮30660片,其中局限型782例12151片,节段型319例8221片,泛发型226例7376片,散发型278例2912片。采用发疱取皮法,受皮区采用CO2激光汽化创面形成,治疗8周后判断疗效。结果治愈率79.04%,有效率13.17%,总有效率92.21%。以局限型和散发型效果最好,泛发型效果较差,身体各部以面部效果最佳,胸背部次之,眉区及发际最差。结论超脉冲CO2激光辅助自体表皮移植治疗白癜风具有操作简单、方便,手术时间短,出血少,皮片易存活,治愈率高的优点,值得临床推广。
Objective To observe the clinical efficacy and safety of ultrapulse CO 2 laser-assisted au-tologous epidermal grafting for the treatment of vitiligo.Methods1605patients with30660skin grafts were treated by CO 2 laser-assisted autologous epidermal grafting.Among them,782patients had localized vi-tiligo,319segmental,226general and278scattered.Epidermal grafts were harvested with negative pressure blistering method from normally pigmented skin,and recipient areas were prepared with a ultrapulse CO 2 laser.The curative effect was evaluated8weeks later.Results79.04%of the lesions were cured complete-ly,and total response rate was92.21%,with better effect in localized and scattered lesions than in other le-sions.The best results were shown in face,while the worst results shown in brow and hairline lesions.Con-clusions The advantage of combined therapy of CO 2 laser with autologous epidermal grafting in vitiligo is of easy performance,convenience,high response rate,which is worthy of large scale application.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2003年第9期493-495,共3页
Chinese Journal of Dermatology
