摘要
目的 :探索有效、安全、价廉的药物 ,以尽可能减少肝癌高发区高危人群的肝癌发生率以及降低肝癌根治性切除后的复发率。方法 :对高危人群 3 91例及术后患者 189例分别分成实验组和对照组。实验组服用纯中药制剂软坚护肝片加甘草甜素片 ,对照组应用一般护肝药。治疗 3年以上 ,长期追踪。结果 :高危人群实验组肝癌发生率 0 72 % ,对照组为 9 9% ,两组比较差异有统计学意义 ,P <0 0 1;术后人群实验组肝癌 3、5年复发率分别为 11 69%和 15 5 8% ,明显低于对照组的 3 0 3 6%和 3 9 2 9% ,P <0 0 5。结论 :软坚护肝片和甘草甜素片对长期暴露于较强肝癌危险因素的人群有良好的保护作用。
OBJECTIVE:To probe into the effective, safe and economical medicine to reduce the incidence of hepatocellular carcinoma(HCC)among high-risk population and the recurrence of patients who underwent radical resection. METHODS: A total of 319 high-risk people and 189 operated patients of HCC were divided into test group and control group respectively. Test group had pure Chinese medicine Ruan Jian Hu Gan Pian and Ga Cao Tian Su Pian for more than 3 years, while the control group had ordinary hepatic medicine. All of them were long-term followed.RESULTS: Among the high-risk people, the incidence of HCC in test group was 0.72% while the rate in control group 9.9%,P<0.01. Among the operated patients, 3- and 5-year recurrences were 11.69% and 15.11% in test group, which were statistically inferior to those in control group with 30.36% and 39.29 respectively, P<0.05. CONCLUSION: Ruan Jian Hu Gan Pian combined with Ga Cao Tian Su Pian has the advantage to protect the high-risk population of HCC.
出处
《肿瘤防治杂志》
2004年第9期907-909,共3页
China Journal of Cancer Prevention and Treatment
关键词
肝肿瘤/预防和控制
肝炎
乙型
肝肿瘤/中药疗法
发病率
liver neoplasms/prevention & control
hepatitis B
liver neoplasms/drug therapy
incidence rate
