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脱氧雪腐镰刀菌烯醇(CBD_1)的毒性探讨:CBD_1对DNA合成的抑制作用观察 被引量:1

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摘要 为了评价 CBD<sub>1</sub>的诱变和/或致癌作用,用<sup>3</sup>(?)-胸腺嘧啶核苷研究 CBD<sub>1</sub>对雄性小鼠睾丸 DNA合成的影(?)。实验结果表明 CBD<sub>1</sub>抑制睾丸 DNA 合成。CBD<sub>1</sub>剂量越大,睾丸 DNA 合成抑制越明显,具有剂量——效应关系。结合 Ames 试验的阳性结果,可初步检测CBD<sub>1</sub>的诱变和/或致癌作用。
机构地区 上海医科大学
出处 《中国食品卫生杂志》 1991年第2期8-10,共3页 Chinese Journal of Food Hygiene
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