When Sir Keir Starmer arrived in Beijing in late January,Britain marked its first prime-ministerial visit to China in eight years.The symbolism was unavoidable.Yet symbolism was not the point.The visit was about recal...When Sir Keir Starmer arrived in Beijing in late January,Britain marked its first prime-ministerial visit to China in eight years.The symbolism was unavoidable.Yet symbolism was not the point.The visit was about recalibrating economic engagement——carefully,and with numbers firmly in hand.展开更多
目的:通过荟萃分析方法系统评估双反牵引复位器与牵引床两种复位方式在老年股骨转子间骨折治疗中的临床效果差异。方法:系统地对多个权威数据库展开检索,涵盖国际上的PubMed、Cochrane Library、EMBASE、Web of Science,以及国内的中国...目的:通过荟萃分析方法系统评估双反牵引复位器与牵引床两种复位方式在老年股骨转子间骨折治疗中的临床效果差异。方法:系统地对多个权威数据库展开检索,涵盖国际上的PubMed、Cochrane Library、EMBASE、Web of Science,以及国内的中国知网、万方数据知识服务平台、维普中文科技期刊数据库和中国生物医学文献服务系统。旨在全面收集有关运用双反牵引复位器和牵引床治疗老年股骨转子间骨折的相关文献资料。随后,对筛选出的文献进行全文精读,精准提取关键效应量数据。最后,借助RevMan5.3软件,对所提取的数据实施荟萃分析,以综合评估两种治疗方式的效果。结果:共纳入文献6篇,485例患者,其中双反牵引组250例,牵引床组235例。双反牵引组手术时间(SMD=-1.32,95%CI-2.13~-0.52,P=0.001)、骨折愈合时间(SMD=-0.58,95%CI-1.11~-0.05,P=0.03)、骨折复位时间(SMD=-11.92,95%CI-3.00~-0.84,P=0.000 5)显著小于牵引床组。两组术中出血量、术后并发症、深静脉血栓形成的差异无统计学意义(P>0.05)。结论:顺势双反牵引器复位对治疗老年股骨转子间骨折治疗效果方面有优势,安全性方面与牵引床治疗无明显差异。展开更多
目的:探讨空心顶棒复位与传统骨拨撬拨切开复位内固定术(Open reduction and Internal Fixation,ORIF)治疗胫骨平台骨折的临床疗效。方法:本研究为回顾性分析,选择通用环球中铁邳州医院2023年1月至2024年6月期间收治的70例胫骨平台骨折...目的:探讨空心顶棒复位与传统骨拨撬拨切开复位内固定术(Open reduction and Internal Fixation,ORIF)治疗胫骨平台骨折的临床疗效。方法:本研究为回顾性分析,选择通用环球中铁邳州医院2023年1月至2024年6月期间收治的70例胫骨平台骨折患者,所有患者均接受锁定钢板固定治疗。根据手术方式将其分为参照组(传统骨拨撬拨ORIF,37例)和试验组(空心顶棒复位固定,33例)。比较两组的围手术期参数(术中出血量、手术总时长、术后完全负重时间、住院时间)、功能康复指标[膝关节活动度、美国特种外科医院(Hospital for Special Surgery,HSS)评分和Lysholm功能评分、Rasmussen功能评分]及术后并发症。结果:与参照组相比,试验组的住院时间、手术总时长、术后完全负重时间更短,术中出血量更少,优良率更高,屈膝最大角度更大,而伸膝最大角度更小(P<0.05)。与参照组术后6个月相比,试验组HSS评分和Lysholm功能评分更高(P<0.05)。两组并发症发生率对比未见差异(P>0.05)。结论:相比于传统骨拨撬拨ORIF,空心顶棒复位治疗胫骨平台骨折,优势较为显著,可缩短手术总时长、住院时间,减少术中出血量,改善膝关节活动度和膝关节功能,安全性好。展开更多
Understanding the mechanisms of parent-daughter isotopic mobility at the nanoscale is key to rigorous interpretation of Ue The Pb data and associated dating. Until now, all nanoscale geochronological studies on geolog...Understanding the mechanisms of parent-daughter isotopic mobility at the nanoscale is key to rigorous interpretation of Ue The Pb data and associated dating. Until now, all nanoscale geochronological studies on geological samples have relied on either Transmission Electron Microscope(TEM) or Atom Probe Microscopy(APM) characterizations alone, thus suffering from the respective weaknesses of each technique. Here we focus on monazite crystals from a ~1 Ga, ultrahigh temperature granulite from Rogaland(Norway). This sample has recorded concordant UeP b dates(measured by LA-ICP-MS) that range over 100 My, with the three domains yielding distinct isotopic Ue Pb ages of 1034 ± 6 Ma(D1; Srich core), 1005 ± 7 Ma(D2), and 935 ± 7 Ma(D3), respectively. Combined APM and TEM characterization of these monazite crystals reveal phase separation that led to the isolation of two different radiogenic Pb(Pb*) reservoirs at the nanoscale. The S-rich core of these monazite crystals contains Cae Srich clusters, 5 -10 nm in size, homogenously distributed within the monazite matrix with a mean interparticle distance of 40 -60 nm. The clusters acted as a sink for radiogenic Pb(Pb*) produced in the monazite matrix, which was reset at the nanoscale via Pb diffusion while the grain remained closed at the micro-scale. Compared to the concordant ages given by conventional micro-scale dating of the grain,the apparent nano-scale age of the monazite matrix in between clusters is about 100 Myr younger, which compares remarkably well to the duration of the metamorphic event. This study highlights the capabilities of combined APM-TEM nano-structural and nano-isotopic characterizations in dating and timing of geological events, allowing the detection of processes untraceable with conventional dating methods.展开更多
Presently,we develop a simplified corticothalamic(SCT)model and propose a single-pulse alternately resetting stimulation(SARS)with sequentially applying anodic(A,“+”)or cathodic(C,“−”)phase pulses to the thalamic ...Presently,we develop a simplified corticothalamic(SCT)model and propose a single-pulse alternately resetting stimulation(SARS)with sequentially applying anodic(A,“+”)or cathodic(C,“−”)phase pulses to the thalamic reticular(RE)nuclei,thalamus-cortex(TC)relay nuclei,and cortical excitatory(EX)neurons,respectively.Abatement effects of ACC-SARS of RE,TC,and EX for the 2 Hz-4 Hz spike and wave discharges(SWD)of absence seizures are then concerned.The m∶n on-off ACC-SARS protocol is shown to effectively reduce the SWD with the least current consumption.In particular,when its frequency is out of the 2 Hz-4 Hz SWD dominant rhythm,the desired seizure abatements can be obtained,which can be further improved by our proposed directional steering(DS)stimulation.The dynamical explanations for the SARS induced seizure abatements are lastly given by calculating the averaged mean firing rate(AMFR)of neurons and triggering averaged mean firing rates(TAMFRs)of 2 Hz-4 Hz SWD.展开更多
文摘When Sir Keir Starmer arrived in Beijing in late January,Britain marked its first prime-ministerial visit to China in eight years.The symbolism was unavoidable.Yet symbolism was not the point.The visit was about recalibrating economic engagement——carefully,and with numbers firmly in hand.
文摘目的:通过荟萃分析方法系统评估双反牵引复位器与牵引床两种复位方式在老年股骨转子间骨折治疗中的临床效果差异。方法:系统地对多个权威数据库展开检索,涵盖国际上的PubMed、Cochrane Library、EMBASE、Web of Science,以及国内的中国知网、万方数据知识服务平台、维普中文科技期刊数据库和中国生物医学文献服务系统。旨在全面收集有关运用双反牵引复位器和牵引床治疗老年股骨转子间骨折的相关文献资料。随后,对筛选出的文献进行全文精读,精准提取关键效应量数据。最后,借助RevMan5.3软件,对所提取的数据实施荟萃分析,以综合评估两种治疗方式的效果。结果:共纳入文献6篇,485例患者,其中双反牵引组250例,牵引床组235例。双反牵引组手术时间(SMD=-1.32,95%CI-2.13~-0.52,P=0.001)、骨折愈合时间(SMD=-0.58,95%CI-1.11~-0.05,P=0.03)、骨折复位时间(SMD=-11.92,95%CI-3.00~-0.84,P=0.000 5)显著小于牵引床组。两组术中出血量、术后并发症、深静脉血栓形成的差异无统计学意义(P>0.05)。结论:顺势双反牵引器复位对治疗老年股骨转子间骨折治疗效果方面有优势,安全性方面与牵引床治疗无明显差异。
文摘目的:探讨空心顶棒复位与传统骨拨撬拨切开复位内固定术(Open reduction and Internal Fixation,ORIF)治疗胫骨平台骨折的临床疗效。方法:本研究为回顾性分析,选择通用环球中铁邳州医院2023年1月至2024年6月期间收治的70例胫骨平台骨折患者,所有患者均接受锁定钢板固定治疗。根据手术方式将其分为参照组(传统骨拨撬拨ORIF,37例)和试验组(空心顶棒复位固定,33例)。比较两组的围手术期参数(术中出血量、手术总时长、术后完全负重时间、住院时间)、功能康复指标[膝关节活动度、美国特种外科医院(Hospital for Special Surgery,HSS)评分和Lysholm功能评分、Rasmussen功能评分]及术后并发症。结果:与参照组相比,试验组的住院时间、手术总时长、术后完全负重时间更短,术中出血量更少,优良率更高,屈膝最大角度更大,而伸膝最大角度更小(P<0.05)。与参照组术后6个月相比,试验组HSS评分和Lysholm功能评分更高(P<0.05)。两组并发症发生率对比未见差异(P>0.05)。结论:相比于传统骨拨撬拨ORIF,空心顶棒复位治疗胫骨平台骨折,优势较为显著,可缩短手术总时长、住院时间,减少术中出血量,改善膝关节活动度和膝关节功能,安全性好。
基金Both UJM and CNRS (INSU TelluS-SYSTER) are thanked for financial support for AMSG and ATL. The Australian Resource Characterisation Facility (ARCF), under the auspices of the National Resource Sciences Precinct (NRSP) - a collaboration between CSIRO, Curtin University and The University of Western Australia e is supported by the Science and Industry Endowment Fund (SIEF RI13-01)
文摘Understanding the mechanisms of parent-daughter isotopic mobility at the nanoscale is key to rigorous interpretation of Ue The Pb data and associated dating. Until now, all nanoscale geochronological studies on geological samples have relied on either Transmission Electron Microscope(TEM) or Atom Probe Microscopy(APM) characterizations alone, thus suffering from the respective weaknesses of each technique. Here we focus on monazite crystals from a ~1 Ga, ultrahigh temperature granulite from Rogaland(Norway). This sample has recorded concordant UeP b dates(measured by LA-ICP-MS) that range over 100 My, with the three domains yielding distinct isotopic Ue Pb ages of 1034 ± 6 Ma(D1; Srich core), 1005 ± 7 Ma(D2), and 935 ± 7 Ma(D3), respectively. Combined APM and TEM characterization of these monazite crystals reveal phase separation that led to the isolation of two different radiogenic Pb(Pb*) reservoirs at the nanoscale. The S-rich core of these monazite crystals contains Cae Srich clusters, 5 -10 nm in size, homogenously distributed within the monazite matrix with a mean interparticle distance of 40 -60 nm. The clusters acted as a sink for radiogenic Pb(Pb*) produced in the monazite matrix, which was reset at the nanoscale via Pb diffusion while the grain remained closed at the micro-scale. Compared to the concordant ages given by conventional micro-scale dating of the grain,the apparent nano-scale age of the monazite matrix in between clusters is about 100 Myr younger, which compares remarkably well to the duration of the metamorphic event. This study highlights the capabilities of combined APM-TEM nano-structural and nano-isotopic characterizations in dating and timing of geological events, allowing the detection of processes untraceable with conventional dating methods.
基金Project supported by the National Natural Science Foundation of China(Nos.11702018,11932003,and 11672074)。
文摘Presently,we develop a simplified corticothalamic(SCT)model and propose a single-pulse alternately resetting stimulation(SARS)with sequentially applying anodic(A,“+”)or cathodic(C,“−”)phase pulses to the thalamic reticular(RE)nuclei,thalamus-cortex(TC)relay nuclei,and cortical excitatory(EX)neurons,respectively.Abatement effects of ACC-SARS of RE,TC,and EX for the 2 Hz-4 Hz spike and wave discharges(SWD)of absence seizures are then concerned.The m∶n on-off ACC-SARS protocol is shown to effectively reduce the SWD with the least current consumption.In particular,when its frequency is out of the 2 Hz-4 Hz SWD dominant rhythm,the desired seizure abatements can be obtained,which can be further improved by our proposed directional steering(DS)stimulation.The dynamical explanations for the SARS induced seizure abatements are lastly given by calculating the averaged mean firing rate(AMFR)of neurons and triggering averaged mean firing rates(TAMFRs)of 2 Hz-4 Hz SWD.
