目的:通过荟萃分析方法系统评估双反牵引复位器与牵引床两种复位方式在老年股骨转子间骨折治疗中的临床效果差异。方法:系统地对多个权威数据库展开检索,涵盖国际上的PubMed、Cochrane Library、EMBASE、Web of Science,以及国内的中国...目的:通过荟萃分析方法系统评估双反牵引复位器与牵引床两种复位方式在老年股骨转子间骨折治疗中的临床效果差异。方法:系统地对多个权威数据库展开检索,涵盖国际上的PubMed、Cochrane Library、EMBASE、Web of Science,以及国内的中国知网、万方数据知识服务平台、维普中文科技期刊数据库和中国生物医学文献服务系统。旨在全面收集有关运用双反牵引复位器和牵引床治疗老年股骨转子间骨折的相关文献资料。随后,对筛选出的文献进行全文精读,精准提取关键效应量数据。最后,借助RevMan5.3软件,对所提取的数据实施荟萃分析,以综合评估两种治疗方式的效果。结果:共纳入文献6篇,485例患者,其中双反牵引组250例,牵引床组235例。双反牵引组手术时间(SMD=-1.32,95%CI-2.13~-0.52,P=0.001)、骨折愈合时间(SMD=-0.58,95%CI-1.11~-0.05,P=0.03)、骨折复位时间(SMD=-11.92,95%CI-3.00~-0.84,P=0.000 5)显著小于牵引床组。两组术中出血量、术后并发症、深静脉血栓形成的差异无统计学意义(P>0.05)。结论:顺势双反牵引器复位对治疗老年股骨转子间骨折治疗效果方面有优势,安全性方面与牵引床治疗无明显差异。展开更多
Understanding the mechanisms of parent-daughter isotopic mobility at the nanoscale is key to rigorous interpretation of Ue The Pb data and associated dating. Until now, all nanoscale geochronological studies on geolog...Understanding the mechanisms of parent-daughter isotopic mobility at the nanoscale is key to rigorous interpretation of Ue The Pb data and associated dating. Until now, all nanoscale geochronological studies on geological samples have relied on either Transmission Electron Microscope(TEM) or Atom Probe Microscopy(APM) characterizations alone, thus suffering from the respective weaknesses of each technique. Here we focus on monazite crystals from a ~1 Ga, ultrahigh temperature granulite from Rogaland(Norway). This sample has recorded concordant UeP b dates(measured by LA-ICP-MS) that range over 100 My, with the three domains yielding distinct isotopic Ue Pb ages of 1034 ± 6 Ma(D1; Srich core), 1005 ± 7 Ma(D2), and 935 ± 7 Ma(D3), respectively. Combined APM and TEM characterization of these monazite crystals reveal phase separation that led to the isolation of two different radiogenic Pb(Pb*) reservoirs at the nanoscale. The S-rich core of these monazite crystals contains Cae Srich clusters, 5 -10 nm in size, homogenously distributed within the monazite matrix with a mean interparticle distance of 40 -60 nm. The clusters acted as a sink for radiogenic Pb(Pb*) produced in the monazite matrix, which was reset at the nanoscale via Pb diffusion while the grain remained closed at the micro-scale. Compared to the concordant ages given by conventional micro-scale dating of the grain,the apparent nano-scale age of the monazite matrix in between clusters is about 100 Myr younger, which compares remarkably well to the duration of the metamorphic event. This study highlights the capabilities of combined APM-TEM nano-structural and nano-isotopic characterizations in dating and timing of geological events, allowing the detection of processes untraceable with conventional dating methods.展开更多
Presently,we develop a simplified corticothalamic(SCT)model and propose a single-pulse alternately resetting stimulation(SARS)with sequentially applying anodic(A,“+”)or cathodic(C,“−”)phase pulses to the thalamic ...Presently,we develop a simplified corticothalamic(SCT)model and propose a single-pulse alternately resetting stimulation(SARS)with sequentially applying anodic(A,“+”)or cathodic(C,“−”)phase pulses to the thalamic reticular(RE)nuclei,thalamus-cortex(TC)relay nuclei,and cortical excitatory(EX)neurons,respectively.Abatement effects of ACC-SARS of RE,TC,and EX for the 2 Hz-4 Hz spike and wave discharges(SWD)of absence seizures are then concerned.The m∶n on-off ACC-SARS protocol is shown to effectively reduce the SWD with the least current consumption.In particular,when its frequency is out of the 2 Hz-4 Hz SWD dominant rhythm,the desired seizure abatements can be obtained,which can be further improved by our proposed directional steering(DS)stimulation.The dynamical explanations for the SARS induced seizure abatements are lastly given by calculating the averaged mean firing rate(AMFR)of neurons and triggering averaged mean firing rates(TAMFRs)of 2 Hz-4 Hz SWD.展开更多
Feldspar Pb isotopes have been widely used to trace magmatic formation and evolution processes.However,it remains unclear whether post-magmatic thermal events can affect feldspar Pb isotopic ratios.Here,the in situ Pb...Feldspar Pb isotopes have been widely used to trace magmatic formation and evolution processes.However,it remains unclear whether post-magmatic thermal events can affect feldspar Pb isotopic ratios.Here,the in situ Pb isotopic composition of feldspar hosted in granitic rocks(thirteen Archean and one Paleoproterozoic)from the northern Kongling terrane,Yangtze Craton,South China,is analyzed.The samples reveal a substantial variation in their Pb isotopic composition,spanning the gap between the 1.9 Ga and present-day geochrons,which indicates extensive resetting by later tectonothermal events.This resetting was interpreted to have likely resulted from Paleoproterozoic and Neoproterozoic tectonothermal events related to the assembly and breakup of the Columbia and Rodinia supercontinents.These results suggest that Pb isotopes should be used cautiously when tracing magma sources and petrogenesis in magmatic rocks that have experienced post-magmatic reworking.However,the in situ Pb isotopic composition of feldspar in ancient granitoids may also potentially be used to reveal later tectonothermal events.The extensive resetting of the Pb isotopic composition in feldspar by regional thermal events may also provide new insights into our understanding of the Pb isotope paradox.展开更多
Time delays exist widely in real systems, and time-delayed interactions can result in abundant dynamic behaviors and functions in dynamic networks. Inferring the time delays and interactions is challenging due to syst...Time delays exist widely in real systems, and time-delayed interactions can result in abundant dynamic behaviors and functions in dynamic networks. Inferring the time delays and interactions is challenging due to systematic nonlinearity,noises, a lack of information, and so on. Recently, Shi et al. proposed a random state variable resetting method to detect the interactions in a continuous-time dynamic network. By arbitrarily resetting the state variable of a driving node, the equivalent coupling functions of the driving node to any response node in the network can be reconstructed. In this paper,we introduce this method in time-delayed dynamic networks. To infer actual time delays, the nearest neighbor correlation(NNC) function for a given time delay is defined. The significant increments of NNC originate from the delayed effect.Based on the increments, the time delays can be reconstructed and the reconstruction errors depend on the sampling time interval. After time delays are accurately identified, the equivalent coupling functions can also be reconstructed. The numerical results have fully verified the validity of the theoretical analysis.展开更多
文摘目的:通过荟萃分析方法系统评估双反牵引复位器与牵引床两种复位方式在老年股骨转子间骨折治疗中的临床效果差异。方法:系统地对多个权威数据库展开检索,涵盖国际上的PubMed、Cochrane Library、EMBASE、Web of Science,以及国内的中国知网、万方数据知识服务平台、维普中文科技期刊数据库和中国生物医学文献服务系统。旨在全面收集有关运用双反牵引复位器和牵引床治疗老年股骨转子间骨折的相关文献资料。随后,对筛选出的文献进行全文精读,精准提取关键效应量数据。最后,借助RevMan5.3软件,对所提取的数据实施荟萃分析,以综合评估两种治疗方式的效果。结果:共纳入文献6篇,485例患者,其中双反牵引组250例,牵引床组235例。双反牵引组手术时间(SMD=-1.32,95%CI-2.13~-0.52,P=0.001)、骨折愈合时间(SMD=-0.58,95%CI-1.11~-0.05,P=0.03)、骨折复位时间(SMD=-11.92,95%CI-3.00~-0.84,P=0.000 5)显著小于牵引床组。两组术中出血量、术后并发症、深静脉血栓形成的差异无统计学意义(P>0.05)。结论:顺势双反牵引器复位对治疗老年股骨转子间骨折治疗效果方面有优势,安全性方面与牵引床治疗无明显差异。
基金Both UJM and CNRS (INSU TelluS-SYSTER) are thanked for financial support for AMSG and ATL. The Australian Resource Characterisation Facility (ARCF), under the auspices of the National Resource Sciences Precinct (NRSP) - a collaboration between CSIRO, Curtin University and The University of Western Australia e is supported by the Science and Industry Endowment Fund (SIEF RI13-01)
文摘Understanding the mechanisms of parent-daughter isotopic mobility at the nanoscale is key to rigorous interpretation of Ue The Pb data and associated dating. Until now, all nanoscale geochronological studies on geological samples have relied on either Transmission Electron Microscope(TEM) or Atom Probe Microscopy(APM) characterizations alone, thus suffering from the respective weaknesses of each technique. Here we focus on monazite crystals from a ~1 Ga, ultrahigh temperature granulite from Rogaland(Norway). This sample has recorded concordant UeP b dates(measured by LA-ICP-MS) that range over 100 My, with the three domains yielding distinct isotopic Ue Pb ages of 1034 ± 6 Ma(D1; Srich core), 1005 ± 7 Ma(D2), and 935 ± 7 Ma(D3), respectively. Combined APM and TEM characterization of these monazite crystals reveal phase separation that led to the isolation of two different radiogenic Pb(Pb*) reservoirs at the nanoscale. The S-rich core of these monazite crystals contains Cae Srich clusters, 5 -10 nm in size, homogenously distributed within the monazite matrix with a mean interparticle distance of 40 -60 nm. The clusters acted as a sink for radiogenic Pb(Pb*) produced in the monazite matrix, which was reset at the nanoscale via Pb diffusion while the grain remained closed at the micro-scale. Compared to the concordant ages given by conventional micro-scale dating of the grain,the apparent nano-scale age of the monazite matrix in between clusters is about 100 Myr younger, which compares remarkably well to the duration of the metamorphic event. This study highlights the capabilities of combined APM-TEM nano-structural and nano-isotopic characterizations in dating and timing of geological events, allowing the detection of processes untraceable with conventional dating methods.
基金Project supported by the National Natural Science Foundation of China(Nos.11702018,11932003,and 11672074)。
文摘Presently,we develop a simplified corticothalamic(SCT)model and propose a single-pulse alternately resetting stimulation(SARS)with sequentially applying anodic(A,“+”)or cathodic(C,“−”)phase pulses to the thalamic reticular(RE)nuclei,thalamus-cortex(TC)relay nuclei,and cortical excitatory(EX)neurons,respectively.Abatement effects of ACC-SARS of RE,TC,and EX for the 2 Hz-4 Hz spike and wave discharges(SWD)of absence seizures are then concerned.The m∶n on-off ACC-SARS protocol is shown to effectively reduce the SWD with the least current consumption.In particular,when its frequency is out of the 2 Hz-4 Hz SWD dominant rhythm,the desired seizure abatements can be obtained,which can be further improved by our proposed directional steering(DS)stimulation.The dynamical explanations for the SARS induced seizure abatements are lastly given by calculating the averaged mean firing rate(AMFR)of neurons and triggering averaged mean firing rates(TAMFRs)of 2 Hz-4 Hz SWD.
基金supported by the Key Laboratory of Gold Mineralization Processes and Resource Utilization,MNRShandong Provincial Key Laboratory of Metallogenic Geological Process and Resource Utilization(Grant No.KFKT202103)National Natural Science Foundation of China(Grant No.41876037)。
文摘Feldspar Pb isotopes have been widely used to trace magmatic formation and evolution processes.However,it remains unclear whether post-magmatic thermal events can affect feldspar Pb isotopic ratios.Here,the in situ Pb isotopic composition of feldspar hosted in granitic rocks(thirteen Archean and one Paleoproterozoic)from the northern Kongling terrane,Yangtze Craton,South China,is analyzed.The samples reveal a substantial variation in their Pb isotopic composition,spanning the gap between the 1.9 Ga and present-day geochrons,which indicates extensive resetting by later tectonothermal events.This resetting was interpreted to have likely resulted from Paleoproterozoic and Neoproterozoic tectonothermal events related to the assembly and breakup of the Columbia and Rodinia supercontinents.These results suggest that Pb isotopes should be used cautiously when tracing magma sources and petrogenesis in magmatic rocks that have experienced post-magmatic reworking.However,the in situ Pb isotopic composition of feldspar in ancient granitoids may also potentially be used to reveal later tectonothermal events.The extensive resetting of the Pb isotopic composition in feldspar by regional thermal events may also provide new insights into our understanding of the Pb isotope paradox.
文摘Time delays exist widely in real systems, and time-delayed interactions can result in abundant dynamic behaviors and functions in dynamic networks. Inferring the time delays and interactions is challenging due to systematic nonlinearity,noises, a lack of information, and so on. Recently, Shi et al. proposed a random state variable resetting method to detect the interactions in a continuous-time dynamic network. By arbitrarily resetting the state variable of a driving node, the equivalent coupling functions of the driving node to any response node in the network can be reconstructed. In this paper,we introduce this method in time-delayed dynamic networks. To infer actual time delays, the nearest neighbor correlation(NNC) function for a given time delay is defined. The significant increments of NNC originate from the delayed effect.Based on the increments, the time delays can be reconstructed and the reconstruction errors depend on the sampling time interval. After time delays are accurately identified, the equivalent coupling functions can also be reconstructed. The numerical results have fully verified the validity of the theoretical analysis.
