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On the microstructural origin of yield point phenomenon and high work-hardening response in fine-grained Mg-3Gd alloy
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作者 Xuan Luo Xianneng Wang +6 位作者 Yiping Xia Guilin Wu Yao Cheng Tianbo Yu Peijie Yan Yunchang Xin Xiaoxu Huang 《Journal of Materials Science & Technology》 2025年第23期290-301,共12页
Mechanical properties of Mg-3Gd(wt.%)samples with average grain sizes ranging from 3 to 45μm were characterized by room temperature tensile test.A reversal of the trade-off,i.e.,high yield strength and large tensile ... Mechanical properties of Mg-3Gd(wt.%)samples with average grain sizes ranging from 3 to 45μm were characterized by room temperature tensile test.A reversal of the trade-off,i.e.,high yield strength and large tensile elongation,was simultaneously observed in the fine-grained samples.The microstructures and hardening response were analyzed in terms of the viewpoint of strain evolution,including local strain evolution by tensile digital image correlation strain measurement,and lattice strain by using synchrotronbased in-situ high energy X-ray diffraction technique.The dislocation-based deformation mechanisms were investigated to underpin the microstructural origin of the yield point phenomenon and enhancement in work-hardening.The occurrence of the yield point phenomenon represented by a yield drop and propagation of the Lüders band is related to the absence of mobile dislocations at an early stage and to the slip transmission between the adjacent grain.The extraordinary work-hardening enhancement over an extended range can be ascribed mainly to the increases in dislocation multiplication and accumulation capabilities by the activation and interaction of multiple slip systems includingand<c+a>types.These results contribute to the design of strong and ductile Mg alloys. 展开更多
关键词 Microstructure Deformation mechanism Yield point phenomenon WORK-HARDENING Mg-3Gd
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Splenic artery aneurysm with double-rupture phenomenon and circulatory collapse following anesthesia induction:A case report
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作者 Guang-Yan Xu Ya-Hong Gong +3 位作者 Yi Wang Xian-Lin Han Chang Hao Li Xu 《World Journal of Clinical Oncology》 2025年第4期291-297,共7页
BACKGROUND Splenic artery aneurysm(SAA)rupture is a rare,life-threatening condition characterized by acute intra-abdominal hemorrhage and hemodynamic instability.Ruptured SAAs may exhibit a biphasic and relatively slo... BACKGROUND Splenic artery aneurysm(SAA)rupture is a rare,life-threatening condition characterized by acute intra-abdominal hemorrhage and hemodynamic instability.Ruptured SAAs may exhibit a biphasic and relatively slow clinical progression,commonly referred to as the“double-rupture phenomenon”.The reported incidence of the double-rupture phenomenon ranges 12%-21%in patients with ruptured SAAs,potentially due to variations in intra-abdominal pressure.Following anesthesia induction,muscle relaxation can decrease intra-abdominal pressure,potentially triggering the double-rupture phenomenon and leading to circulatory collapse.CASE SUMMARY A 61-year-old female presented to the Department of Emergency with upper abdominal pain,abdominal distension,dizziness,and vomiting.Her vital signs were initially stable.Physical examination revealed abdominal tenderness and positive-shifting dullness.Abdominal contrast-enhanced computed tomography revealed cirrhosis,severe portal hypertension,and splenomegaly.Acute rupture was suggested by a hematoma on the upper left side outside the SAA.Surgeons deemed intravascular intervention challenging and open splenectomy inevitable.Circulatory collapse occurred after anesthesia induction,likely due to a double rupture of the SAA.This double-rupture phenomenon may have resulted from an initial rupture of the SAA into the omental bursa,forming a hematoma that exerted a tamponade effect.A second rupture into the peritoneal cavity may have been triggered by decreased intra-abdominal pressure following anesthesia induction.The patient’s life was saved through early,coordinated,multidisciplinary significant postoperative bleeding or hypoxic encephalopathy.CONCLUSION Anesthesia-induced pressure reduction may trigger a second SAA rupture,causing collapse.Early diagnosis and multidisciplinary teamwork improve outcomes.This is a rare and life-threatening case of SAA rupture,which is of great significance to the medical community for understanding and handling such emergencies. 展开更多
关键词 Splenic artery aneurysm Double-rupture phenomenon Circulatory collapse Anesthesia induction Case report
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Goalie Phenomenon: Unveiling Hidden Health Conditions in Young Athletes
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作者 Jaber H.Jaradat Rawan Hamamreh Abdulqadir J.Nashwan 《Health Care Science》 2025年第6期424-426,共3页
1|Goalie Phenomenon The goalie phenomenon describes a group of health issues that may become apparent in children who prefer playing as goalkeepers.This preference might not only be about the excitement of the role bu... 1|Goalie Phenomenon The goalie phenomenon describes a group of health issues that may become apparent in children who prefer playing as goalkeepers.This preference might not only be about the excitement of the role but also as a coping mechanism for underlying health issues that make continuous running and high physical exertion challenging.The term highlights how certain positions in sports can sometimes obscure or reveal hidden health conditions,particularly among young athletes[1–3].To our knowledge,this is the first paper to formally introduce the term“Goalie phenomenon”in the literature exploring exerciseinduced asthma and sports role preferences in children. 展开更多
关键词 young athletes exercise induced asthma coping mechanism goalie phenomenon sports role preferences health conditions
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Denoising graph neural network based on zero-shot learning for Gibbs phenomenon in high-order DG applications
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作者 Wei AN Jiawen LIU +3 位作者 Wenxuan OUYANG Haoyu RU Xuejun LIU Hongqiang LYU 《Chinese Journal of Aeronautics》 2025年第3期234-248,共15页
With the availability of high-performance computing technology and the development of advanced numerical simulation methods, Computational Fluid Dynamics (CFD) is becoming more and more practical and efficient in engi... With the availability of high-performance computing technology and the development of advanced numerical simulation methods, Computational Fluid Dynamics (CFD) is becoming more and more practical and efficient in engineering. As one of the high-precision representative algorithms, the high-order Discontinuous Galerkin Method (DGM) has not only attracted widespread attention from scholars in the CFD research community, but also received strong development. However, when DGM is extended to high-speed aerodynamic flow field calculations, non-physical numerical Gibbs oscillations near shock waves often significantly affect the numerical accuracy and even cause calculation failure. Data driven approaches based on machine learning techniques can be used to learn the characteristics of Gibbs noise, which motivates us to use it in high-speed DG applications. To achieve this goal, labeled data need to be generated in order to train the machine learning models. This paper proposes a new method for denoising modeling of Gibbs phenomenon using a machine learning technique, the zero-shot learning strategy, to eliminate acquiring large amounts of CFD data. The model adopts a graph convolutional network combined with graph attention mechanism to learn the denoising paradigm from synthetic Gibbs noise data and generalize to DGM numerical simulation data. Numerical simulation results show that the Gibbs denoising model proposed in this paper can suppress the numerical oscillation near shock waves in the high-order DGM. Our work automates the extension of DGM to high-speed aerodynamic flow field calculations with higher generalization and lower cost. 展开更多
关键词 Computational fluid dynamics High-order discon tinuous Galerkin method Gibbs phenomenon Graph neural networks Zero-shot learning
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低速重载输送链传动系统动力学建模及特性研究
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作者 陈立锋 张俊博 肖钊 《机械传动》 北大核心 2026年第1期87-91,共5页
【目的】针对低速重载输送链传动存在的爬行现象及运动平稳性差的问题,基于多刚体动力学理论,建立了低速重载输送链传动动力学模型,开展了动力学特性研究,为提高低速重载输送链传动系统的平稳性提供参考。【方法】考虑低速重载输送链传... 【目的】针对低速重载输送链传动存在的爬行现象及运动平稳性差的问题,基于多刚体动力学理论,建立了低速重载输送链传动动力学模型,开展了动力学特性研究,为提高低速重载输送链传动系统的平稳性提供参考。【方法】考虑低速重载输送链传动系统的结构特点及输送载荷的影响,利用胡克定律模拟输送链节点的力学特性,构建了输送链107自由度动力学模型;采用模态叠加法对动力学模型进行求解,得到了低速重载输送链的动力学特性,研究了输送链的松边悬垂度和紧边摩擦力对传动速度变化的影响规律。【结果】结果表明,降低松边悬垂度、减小链条与导轨间的摩擦因数,可有效减少输送链传动爬行现象的产生,提高输送链传动系统的运动平稳性。 展开更多
关键词 输送链传动 平稳性 爬行现象 动力学 模态叠加
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Overflowing phenomenon during ultrasonic treatment in Al-Si alloys 被引量:5
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作者 张宇博 卢一平 +3 位作者 接金川 傅莹 钟德水 李廷举 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2013年第11期3242-3248,共7页
At the late stage of solidification with ultrasonic treatment (UST) in Al-Si alloys, a part of semisolid overflows and climbs along the probe. The interesting phenomenon and its influence on the solidification micro... At the late stage of solidification with ultrasonic treatment (UST) in Al-Si alloys, a part of semisolid overflows and climbs along the probe. The interesting phenomenon and its influence on the solidification microstructure were investigated in order to better study the mechanism of UST. It is considered that the overflowing phenomenon occurs due to the changes of vibration and flow in the remaining semisolid. Because the overflowed portion comes from the region with intense UST effect and vibrates with the probe during solidification, great modification of primary and euteetic Si (about 10 pm in length) and refinement of primary a(Al) (about 70 μm in size) are observed in this portion. 展开更多
关键词 Al-Si alloy ultrasonic treatment overflowing phenomenon solidification microstructure
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INFLUENCE OF VIRTUAL PHOTON FIELD ON COLLAPSE AND REVIVAL PHENOMENON IN TWO PHOTON J C MODEL WITHOUT RWA
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作者 杨雁南 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 1999年第1期86-92,共7页
The time evolution of system in two photon Jaynes Cummings (J C) model without rotating waves approximation (RWA) is obtained by using the theory of ordinary differential equations. Based on the evolution, the mean ... The time evolution of system in two photon Jaynes Cummings (J C) model without rotating waves approximation (RWA) is obtained by using the theory of ordinary differential equations. Based on the evolution, the mean value of the atom inversion operator 〈 S 3(t)〉 is gi ven. The influence of the “counter rotating term” on the collapse and revival phenomenon is discussed from the comparison between the cases with RWA and without RWA. It shows that the influence of the virtual photon field makes the quantum fluctuations appear on the collapse and revival phenomenon. 展开更多
关键词 PHOTONS quantum noise J C model rotating waves approximation collapse and revival phenomenon atom inversion operator
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浅谈连铸中间包工作衬用镁质喷涂料的滴水问题
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作者 宋荣飞 王永军 +1 位作者 闫道芳 娄军峰 《耐火与石灰》 2026年第1期25-28,共4页
镁质喷涂料目前在连铸中间包工作衬使用比较普遍,但这种内衬的中间包经常在连铸平台上烘烤过程中或者浇钢前期出现滴水现象,水分如果进入浇铸的钢坯中,会影响钢材质量,这个问题一直困扰着连铸浇钢。经过现场跟踪调研,对滴水产生的原因... 镁质喷涂料目前在连铸中间包工作衬使用比较普遍,但这种内衬的中间包经常在连铸平台上烘烤过程中或者浇钢前期出现滴水现象,水分如果进入浇铸的钢坯中,会影响钢材质量,这个问题一直困扰着连铸浇钢。经过现场跟踪调研,对滴水产生的原因进行分析研究,提出了一些改进措施,中间包滴水现象有了很明显的控制与改善。 展开更多
关键词 中间包 喷涂料 滴水现象 原因分析 改进措施
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关于《纯粹理性批判》中“Appearance”与“Phenomenon”的翻译
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作者 刘蕴秋 傅小凡 《保定师专学报》 2000年第3期18-19,73,共3页
康德《纯粹理性批判》中“Appearance”与“Phenomenon”既存在本体论、认识论意义上的差异 ,又存在具体与抽象、变化规定与实体永恒。
关键词 康德 《纯粹理性批判》 "Appwearance" "Phwencmenon" 词义辨析 词语翻译
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西部民族地区高职生“慢就业”现象影响因素研究 ——基于对广西14所高职院校大学生的调研
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作者 莫云 余茵 《西部学刊》 2026年第1期17-20,共4页
以广西区内14所高职院校学生为调研对象,深入分析其“慢就业”现状及影响因素,并提出针对性解决策略。调研发现,有过半数高职生对“慢就业”持平和态度,但“慢就业”现象在民族地区呈消极化趋势,且多数学生实际并不愿选择“慢就业”。... 以广西区内14所高职院校学生为调研对象,深入分析其“慢就业”现状及影响因素,并提出针对性解决策略。调研发现,有过半数高职生对“慢就业”持平和态度,但“慢就业”现象在民族地区呈消极化趋势,且多数学生实际并不愿选择“慢就业”。影响因素分析表明,社会就业竞争激烈,学校人才培养与就业指导衔接不足,家庭求稳观念与物质基础的包容性以及个人能力与求职理想的差距是导致该现象出现的主要原因。基于此,提出以下解决策略:一是高职生需转变观念,明确职业规划,提升专业技能,激发就业内生动力;二是高校应完善就业指导体系,深化校企合作,搭建精准就业信息平台;三是家庭应理性看待就业,鼓励自立自强,支持多元化就业选择;四是社会需加大就业扶持力度,优化职业教育体系,整合资源提供多元化支持。 展开更多
关键词 民族地区 高职生 “慢就业”现象 广西 高职院校
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Dynamic modeling of a hose-drogue aerial refueling system and integral sliding mode backstepping control for the hose whipping phenomenon 被引量:22
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作者 Wang Haitao Dong Xinmin +1 位作者 Xue Jianping Liu Jiaolong 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2014年第4期930-946,共17页
Dynamic modeling of a hose-drogue aerial refueling system(HDARS)and an integral sliding mode backstepping controller design for the hose whipping phenomenon(HWP)during probe-drogue coupling are studied.Firstly,a dynam... Dynamic modeling of a hose-drogue aerial refueling system(HDARS)and an integral sliding mode backstepping controller design for the hose whipping phenomenon(HWP)during probe-drogue coupling are studied.Firstly,a dynamic model of the variable-length hose-drogue assembly is built for the sake of exploiting suppression methods for the whipping phenomenon.Based on the lumped parameter method,the hose is modeled by a series of variable-length links connected with frictionless joints.A set of iterative equations of the hose's three-dimensional motion is derived subject to hose reeling in/out,tanker motion,gravity,and aerodynamic loads accounting for the effects of steady wind,atmospheric turbulence,and tanker wake.Secondly,relying on a permanent magnet synchronous motor and high-precision position sensors,a new active control strategy for the HWP on the basis of the relative position between the tanker and the receiver is proposed.Considering the strict-feedback configuration of the permanent magnet synchronous motor,a rotor position control law based on the backstepping method is designed to insure global stability.An integral of the rotor position error and an exponential sliding mode reaching law of the current errors are applied to enhance control accuracy and robustness.Finally,the simulation results show the effectiveness of the proposed model and control laws. 展开更多
关键词 Aerial refueling BACKSTEPPING Hose drogue assembly Permanent magnet synchronous motor Sliding mode Whipping phenomenon
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Genetic pattern of belt-wide petroliferous phenomenon in the eastern Pearl River Mouth Basin and its practical application 被引量:14
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作者 Shi Hesheng Dai Yiding +2 位作者 Liu Lihua Shu Yu Mei Lianfu 《Petroleum Science》 SCIE CAS CSCD 2014年第1期1-13,共13页
The Pearl River Mouth Basin (PRMB) covers an area of approximately 20× 104 km2.However,oil-gas fields detected in this area thus far are highly concentrated and controlled predominantly by second-order structur... The Pearl River Mouth Basin (PRMB) covers an area of approximately 20× 104 km2.However,oil-gas fields detected in this area thus far are highly concentrated and controlled predominantly by second-order structural belts,the seven largest of which aggregate proved oil reserves of 7.7× 108 m3,accounting for 86% of the total discovered reserve in the basin.These second-order structures have one common phenomenon:oil is contained in all traps present in them.In other words,they are all belt-wide petroliferous reservoirs.Research has identified eight types of second-order structural belts under two categories in the eastern PRMB.Their petroliferous properties are subject to three typical constraints:petroliferous properties of subsags hosting these structural belts,locations of these belts in the petroleum system,and availability of traps prior to the hydrocarbon expulsion and migration.The formation and distribution of oil reservoirs in these belts are characterized by subsag-belt integration and "three-in-one".The former indicates that sags and the second-order structural belts within the supply range of the sags constitute the basic units of hydrocarbon accumulations and are therefore inseparable.The latter indicates that a belt-wide petroliferous second-order structural belt always contains three important elements:hydrocarbon richness,effective pathway and pre-existing traps. 展开更多
关键词 Pearl River Mouth Basin belt-wide petroliferous phenomenon second-order structural belt petroleum exploration
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Variational iteration solving method for El Nio phenomenon atmospheric physics of nonlinear model 被引量:14
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作者 MO Jiaqi WANG Hui +1 位作者 LIN Wantao LIN Yihua 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2005年第5期35-38,共4页
A class of E1 Niйo atmospheric physics oscillation model is considered. The E1 Niйo atmospheric physics oscillation is an abnormal phenomenon involved in the tropical Pacific ocean-atmosphere interactions. The conce... A class of E1 Niйo atmospheric physics oscillation model is considered. The E1 Niйo atmospheric physics oscillation is an abnormal phenomenon involved in the tropical Pacific ocean-atmosphere interactions. The conceptual oscillator model should consider the variations of both the eastern and western Pacific anomaly patterns. An E1 Niйo atmospheric physics model is proposed using a method for the variational iteration theory. Using the variational iteration method, the approximate expansions of the solution of corresponding problem are constructed. That is, firstly, introducing a set of functional and accounting their variationals, the Lagrange multiplicators are counted, and then the variational iteration is defined, finally, the approximate solution is obtained. From approximate expansions of the solution, the zonal sea surface temperature anomaly in the equatorial eastern Pacific and the thermocline depth anomaly of the sea-air oscillation for E1 Niйo atmospheric physics model can be analyzed. E1 Niйo is a very complicated natural phenomenon. Hence basic models need to be reduced for the sea-air oscillator and are solved. The variational iteration is a simple and valid approximate method. 展开更多
关键词 NONLINEAR variational iteration method E1 Niйo phenomenon
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Microstructure and yield phenomenon of an extruded Mg-Y-Cu alloy with LPSO phase 被引量:20
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作者 Guangli Bi Niuming Zhang +6 位作者 Jing Jiang Yuandong Li Tijun Chen Wei Fu Xiaoru Zhang Daqing Fang Xiangdong Ding 《Journal of Rare Earths》 SCIE EI CAS CSCD 2023年第3期454-461,I0005,共9页
A yield phenomenon was firstly reported in an extruded Mg-6.8Y-2.5Cu alloy and the corresponding microstructure was also investigated in this work,The cast alloy is mainly composed ofα-Mg,18R long period stacking ord... A yield phenomenon was firstly reported in an extruded Mg-6.8Y-2.5Cu alloy and the corresponding microstructure was also investigated in this work,The cast alloy is mainly composed ofα-Mg,18R long period stacking order(LPSO)phase,eutectic phase(Mg_(20)Cu_(4)Y_(1)),and Mg_(2)Cu phase.The 18R LPSO phase at the dendritic grain boundary transforms into the 14H LPSO phase in the grain interior during homogenization.After extrusion,the grain size of the homogenized alloy is remarkably refined to-3.69μm and the second phase is significantly broken and distributed in the extrusion direction.Tensile testing curves of the extrude alloy at room temperature indicate that the yield strength and ultimate tensile strength increase while the elongation of the alloy decreases with increasing strain rate.Interestingly,a yield plateau fo rms and gradually decreases with increasing strain rate.The yield phenomenon is related to the dislocation multiplication and the interaction between the movable dislocations and solute atoms. 展开更多
关键词 Extruded Mg-6.8Y-2.5Cu alloy Long period stacking order phase MICROSTRUCTURE Yield phenomenon Rare earths
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Fluid Flow and Interfacial Phenomenon of Slag and Metal in Continuous Casting Tundish With Argon Blowing 被引量:5
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作者 WANG Jun ZHU Miao-yong ZHOU Hai-bing WANG Ying 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2008年第4期26-31,共6页
The fluid flow and the interfacial phenomenon of slag and metal in tundish with gas blowing were studied with mathematical and physical modeling, and the effects of gas flowrate, the placement of porous beam for the g... The fluid flow and the interfacial phenomenon of slag and metal in tundish with gas blowing were studied with mathematical and physical modeling, and the effects of gas flowrate, the placement of porous beam for the generation of bubbles, and the combination of flow control devices on the flow and slag-metal interface were investigated. The results show that the position of gas bubbling has a significant effect on the flow in tundish, and the placement of porous beam and gas flowrate are the two main factors affecting the entrapment of slag in tundish. The closer the porous beam to the weir, the more reasonable is the flow, which is in favor of the control of slag entrapment in tundish. 展开更多
关键词 continuous casting tundish argon blowing fluid flow interfacial phenomenon SLAG METAL slag entrapment mathematical modeling physical modeling
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Relatedness between catalytic effect of activated carbon and passivation phenomenon during chalcopyrite bioleaching by mixed thermophilic Archaea culture at 65°C 被引量:7
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作者 Ya-long MA Hong-chang LIU +7 位作者 Jin-lan XIA Zhen-yuan NIE Hong-rui ZHU Yi-dong ZHAO Chen-yan MA Lei ZHENG Cai-hao HONG Wen WEN 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2017年第6期1374-1384,共11页
The relatedness between catalytic effect of activated carbon and passivation phenomenon during chalcopyrite bioleachingby mixed thermophilic Archaea culture(Acidianus brierleyi,Metallosphaera sedula,Acidianus manzaens... The relatedness between catalytic effect of activated carbon and passivation phenomenon during chalcopyrite bioleachingby mixed thermophilic Archaea culture(Acidianus brierleyi,Metallosphaera sedula,Acidianus manzaensis and Sulfolobusmetallicus)at65°C was studied.Leaching experiments showed that the addition of activated carbon could significantly promote thedissolution of chalcopyrite for both bioleaching and chemical leaching.The results of synchrotron-based X-ray diffraction,ironL-edge and sulfur K-edge X-ray absorption near edge structure spectroscopy indicated that activated carbon could change thetransition path of electrons through galvanic interactions to form more readily dissolved secondary mineral chalcocite at a low redoxpotential(?400mV)and then enhanced the copper dissolution.Jarosite accumulated immediately in the initial stage of bioleachingwith activated carbon but copper dissolution was not hindered.However,much jarosite precipitated on the surface of chalcopyrite inthe late stage of bioleaching,which might account for the decrease of copper dissolution rate.More elemental sulfur(S0)was alsodetected with additional activated carbon but the mixed thermophilic Archaea culture had a great sulfur oxidation activity,thus S0waseliminated and seemed to have no significant influence on the dissolution of chalcopyrite. 展开更多
关键词 CHALCOPYRITE BIOLEACHING activated carbon passivation phenomenon mixed thermophilic Archaea culture
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Optimization of Baffled Rectangular and Prismatic Storage Tank Against the Sloshing Phenomenon 被引量:8
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作者 Hassan SAGHI NING De-zhi +1 位作者 CONG Pei-wen ZHAO Ming 《China Ocean Engineering》 SCIE EI CSCD 2020年第5期664-676,共13页
The fluid motion in partially filled tanks with internal baffles has wide engineering applications. The installation of baffles is expected to reduce the effect of sloshing as well as the consequent environmental dama... The fluid motion in partially filled tanks with internal baffles has wide engineering applications. The installation of baffles is expected to reduce the effect of sloshing as well as the consequent environmental damages. In the present study, a series of experimental tests are performed to investigate the sloshing phenomenon in a baffled rectangular storage tank. In addition, the sloshing phenomenon is also modeled by using Open Foam. Based on the experimental and numerical studies, optimization of the geometric parameters of the tank is performed based on some criteria such as tank area, entropy generation, and the horizontal force exerted on the tank area due to the sloshing phenomenon.The optimization is also carried out based on the entropy generation minimization analysis. It is noted that the optimum baffle height is in the range of h_b/h_w=0.5-0.75 in the present study(where h_b and h_w are the baffle height and water depth, respectively). Based on the results, the optimal design of the tank is achieved with R_A= 0.9-1.0(where R_A=L/W, L and W are the length and width of the tank, respectively). The results also show that the increase of h_b can lead to a decrease of the maximum pressure and horizontal force exerted on the tank. It is also noted that the horizontal force exerted on the tank firstly continues to increase as the sway motion amplitude increases.However, as the normalized motion amplitude parameter, a/L(The parameter a is the motion amplitude), exceeds0.067, the effect of motion amplitude on the force is not obvious. The same optimization is also performed in the multiple-variable-baffled tank and prismatic storage tank. 展开更多
关键词 baffled rectangular storage tank experimental tests sloshing phenomenon OPTIMIZATION entropy generation Open Foam
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The effect of monosialylganglioside mix modifying the PEGylated liposomal epirubicin on the accelerated blood clearance phenomenon 被引量:4
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作者 Ting Zhang Songlei Zhou +5 位作者 Le Kang Xiang Luo Yang Liu Yanzhi Song Xinrong Liu Yihui Deng 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2017年第2期134-142,共9页
PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. Howev... PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. However, PEG-modified liposomes can induce accelerated blood clearance(ABC) upon repeated administration, and the extent of ABC phenomenon on the cytotoxic drugs-containing PEGylated liposomes is related to the dose of the cytotoxic drugs.In this study, EPI served as a model cytotoxic drug, a hydrophilic surfactant molecule,monosialylganglioside(GM1) was chosen and modified on the liposomes together with PEG.It was shown that upon mixed modification, when GM1 contents reached 10% or 15% mol,the ABC phenomenon of the PEGylated liposomal EPI significantly reduced. We also found that GM1 played an important role in abrogating the ABC phenomenon in both the induction phase and the effectuation phase. The results suggested that GM1 incorporation unfortunately did not avoid occurrence of ABC phenomenon completely, but GM1 modification on PEGylated liposomes may provide a significant improvement in clinical practice of PEGylated liposomes. Further study must be necessary. 展开更多
关键词 PEGylated liposomes EPIRUBICIN Monosialylganglioside(GM1) Mixed modification Accelerated blood CLEARANCE (ABC) phenomenon
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Effect of injection scheme on asymmetric phenomenon in rectangular and circular scramjets 被引量:4
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作者 Guangwei MA Mingbo SUN +3 位作者 Guoyan ZHAO Changhai LIANG Hongbo WANG Jiangfei YU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2023年第1期216-230,共15页
The asymmetric separation has a crucial effect on the performance of the scramjet.In this study,the asymmetric separation and combustion in both rectangular and circular scramjets are investigated numerically,and the ... The asymmetric separation has a crucial effect on the performance of the scramjet.In this study,the asymmetric separation and combustion in both rectangular and circular scramjets are investigated numerically,and the effect of injection scheme is analyzed.The characteristics of the flow field are analyzed based on sufficient code verification.In the rectangular scramjet,the separation tends to occur in the corner due to the corner boundary-layer effect.The separation is asym-metric and only two corners have serious separation.The fuel penetration depth in the separation zone increases and the combustion is intensified.When the injection scheme is uniform,both the combustion and separation become weak.In the circular scramjet,the separation and combustion are basically axisymmetric in the scramjet with one-row injection scheme.The asymmetric combustion becomes obvious in cases with multi-row injection scheme.When the injection orifices distribute intensively on the top and bottom sides,the strongest and weakest separations occur near these two sides respectively.When the distribution of orifices becomes uniform,the direction of separation cannot be predicted.For multi-row cases,the nonuniform injection scheme could result in violent combustion and asymmetric flow structures compared with the uniform injection scheme. 展开更多
关键词 Asymmetric phenomenon Cavity Combustion Injection scheme SCRAMJET SUPERSONIC
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