Needleless electrospinning is a versatile method to produce nanofibers.In particular,the rotary version of this technique has enjoyed widespread use because there is no need to clean the spinneret.The rotation speed i...Needleless electrospinning is a versatile method to produce nanofibers.In particular,the rotary version of this technique has enjoyed widespread use because there is no need to clean the spinneret.The rotation speed is limited by the potential deviation of the jet due to the centrifugal force.Other limitations are due to the fast volatilization of the solvent from the opened spinning system.In order to overcome these drawbacks,here a novel reciprocating system based on a moving spinning-plate is proposed.The spinning process is implemented in a half-closed system with the spinning-plate immersed in the solution tank.When the immersed spinning-plate moves up from the solution tank,multiple jets are ejected from the droplets on the tips of the spinning-plate under the effect of an electric field force.The morphology of the obtained nanofibers has been analyzed by scanning electron microscopy.The results indicated that the obtained fibers are uniform in structures and small in diameters.Both issues of needle clogging and intense solvent evaporation can be mitigated using this alternate approach.展开更多
<strong>Objectives</strong>: <span style="font-family:;" "=""><span>The aim of this thesis is to determine the clinical effectiveness, safety and cost-effectiveness of ...<strong>Objectives</strong>: <span style="font-family:;" "=""><span>The aim of this thesis is to determine the clinical effectiveness, safety and cost-effectiveness of Single Incision needleless Mini-Slings compared with tension-free Standard Mid-urethral Sling in the surgical management of female stress urinary incontinence, but with less side effects. </span><b><span>Methods:</span></b><span> The study will be conducted in Zagazig University Hospitals. From 2018 to Sept. 2019, 40 cases were enrolled in the study and were randomized by envelope technique at the time of surgery to either a trans-obturator vaginal tape (TOT) or Needleless anti-incontinence procedure. The patients will be divided into 2 groups: Group 1 patient treated by standard sling (TOT). Group 2 those treated by mini-sling. Parameters in perioperative period such as operating time, intraoperative hemorrhage volume, length of stay in hospital, intraoperative complications, and postoperative pain of each patient were recorded. The sample size was calculated to be 40 cases (20 cases will be treated by standard slings, 20 case will be treated by mini-sling). </span><b><span>Results: </span></b><span>A total of 40 patients assessed for eligibility were randomized into Needleless groups. There were no significant differences in age, body mass index, process, parity, pad test or the assessment of preoperative quality of life between the two groups. In the perioperative period, statistically significant differences between the two groups were found in operating time, intraoperative hemorrhage volume, groin pain scores at 24 h after operation and length of stay in hospital (P < 0.001). After two weeks of follow-up, a statistically significant difference between the two groups was found in groin pain/femori-bus internus pain scores, but there were no significant differences in cure rates, pad test, complications or ICIQ-SF. After 1 year, there were no significant differences between the Needleless and TOT groups in cure rates, pad test, groin pain or ICIQ-SF (P > 0.05). Both groups registered a significant improvement in the quality of life (P < 0.001), but there were no significant differences between the two groups (P > 0.05). </span><b><span>Conclusion: </span></b><span>We conclude that compared with the TOT surgery, single-incision Needleless sling in the treatment of female stress urinary incontinence is simpler and quicker and has less hemorrhage during surgery as well as faster recovery and it also can obviously reduce the inguinal region pains after operation and shorten hospital stays. In summary, single-incision Needleless sling is a kind of convenient, safe and effective minimally invasive surgery for urinary incontinence.</span></span>展开更多
目的对消毒帽在静脉导管无针接头消毒中应用的研究进行范围综述。方法系统检索PubMed、Web of Science、Embase、The Cochrane Library、中国知网(CNKI)、万方及中国生物医学文献数据库中有关消毒帽在静脉导管无针接头消毒中应用的文献...目的对消毒帽在静脉导管无针接头消毒中应用的研究进行范围综述。方法系统检索PubMed、Web of Science、Embase、The Cochrane Library、中国知网(CNKI)、万方及中国生物医学文献数据库中有关消毒帽在静脉导管无针接头消毒中应用的文献,检索时限为建库至2024年8月22日。结果共纳入18篇文献,目前国外被广泛应用于临床实践的消毒帽产品主要有Curos^(TM)、SwabCap^(TM)2种。大部分文献显示消毒帽在预防或减少导管相关血流感染(catheter related blood stream infection,CRBSI)方面具有一定的作用,消毒帽临床应用简单、护士体验较好,具备一定的成本效益。结论多数消毒帽产品的有效成分为70%异丙醇,可通过与无针接头连接摩擦对静脉导管进行消毒并提供物理屏障,但临床上消毒帽应用的有效性和安全性仍需进一步探索。展开更多
基金The work is supported by Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD),National Natural Science Foundation of China under Grant No.11372205.
文摘Needleless electrospinning is a versatile method to produce nanofibers.In particular,the rotary version of this technique has enjoyed widespread use because there is no need to clean the spinneret.The rotation speed is limited by the potential deviation of the jet due to the centrifugal force.Other limitations are due to the fast volatilization of the solvent from the opened spinning system.In order to overcome these drawbacks,here a novel reciprocating system based on a moving spinning-plate is proposed.The spinning process is implemented in a half-closed system with the spinning-plate immersed in the solution tank.When the immersed spinning-plate moves up from the solution tank,multiple jets are ejected from the droplets on the tips of the spinning-plate under the effect of an electric field force.The morphology of the obtained nanofibers has been analyzed by scanning electron microscopy.The results indicated that the obtained fibers are uniform in structures and small in diameters.Both issues of needle clogging and intense solvent evaporation can be mitigated using this alternate approach.
文摘<strong>Objectives</strong>: <span style="font-family:;" "=""><span>The aim of this thesis is to determine the clinical effectiveness, safety and cost-effectiveness of Single Incision needleless Mini-Slings compared with tension-free Standard Mid-urethral Sling in the surgical management of female stress urinary incontinence, but with less side effects. </span><b><span>Methods:</span></b><span> The study will be conducted in Zagazig University Hospitals. From 2018 to Sept. 2019, 40 cases were enrolled in the study and were randomized by envelope technique at the time of surgery to either a trans-obturator vaginal tape (TOT) or Needleless anti-incontinence procedure. The patients will be divided into 2 groups: Group 1 patient treated by standard sling (TOT). Group 2 those treated by mini-sling. Parameters in perioperative period such as operating time, intraoperative hemorrhage volume, length of stay in hospital, intraoperative complications, and postoperative pain of each patient were recorded. The sample size was calculated to be 40 cases (20 cases will be treated by standard slings, 20 case will be treated by mini-sling). </span><b><span>Results: </span></b><span>A total of 40 patients assessed for eligibility were randomized into Needleless groups. There were no significant differences in age, body mass index, process, parity, pad test or the assessment of preoperative quality of life between the two groups. In the perioperative period, statistically significant differences between the two groups were found in operating time, intraoperative hemorrhage volume, groin pain scores at 24 h after operation and length of stay in hospital (P < 0.001). After two weeks of follow-up, a statistically significant difference between the two groups was found in groin pain/femori-bus internus pain scores, but there were no significant differences in cure rates, pad test, complications or ICIQ-SF. After 1 year, there were no significant differences between the Needleless and TOT groups in cure rates, pad test, groin pain or ICIQ-SF (P > 0.05). Both groups registered a significant improvement in the quality of life (P < 0.001), but there were no significant differences between the two groups (P > 0.05). </span><b><span>Conclusion: </span></b><span>We conclude that compared with the TOT surgery, single-incision Needleless sling in the treatment of female stress urinary incontinence is simpler and quicker and has less hemorrhage during surgery as well as faster recovery and it also can obviously reduce the inguinal region pains after operation and shorten hospital stays. In summary, single-incision Needleless sling is a kind of convenient, safe and effective minimally invasive surgery for urinary incontinence.</span></span>
文摘目的对消毒帽在静脉导管无针接头消毒中应用的研究进行范围综述。方法系统检索PubMed、Web of Science、Embase、The Cochrane Library、中国知网(CNKI)、万方及中国生物医学文献数据库中有关消毒帽在静脉导管无针接头消毒中应用的文献,检索时限为建库至2024年8月22日。结果共纳入18篇文献,目前国外被广泛应用于临床实践的消毒帽产品主要有Curos^(TM)、SwabCap^(TM)2种。大部分文献显示消毒帽在预防或减少导管相关血流感染(catheter related blood stream infection,CRBSI)方面具有一定的作用,消毒帽临床应用简单、护士体验较好,具备一定的成本效益。结论多数消毒帽产品的有效成分为70%异丙醇,可通过与无针接头连接摩擦对静脉导管进行消毒并提供物理屏障,但临床上消毒帽应用的有效性和安全性仍需进一步探索。
