摘要
目的探讨32P敷贴结合无针缝合器治疗前胸瘢痕疙瘩的临床疗效。方法回顾分析180例前胸瘢痕疙瘩患者治疗的疗效,其中将60例病变厚度≤0.2 cm的患者随机分为3组,复方倍他米松注射组20例,单纯32P敷贴组20例,无针缝合器+32P敷贴组20例;120例病变厚度>0.2 cm的患者随机分为4组,复方倍他米松注射组30例,单纯32P敷贴组30例,手术+32P敷贴组30例,无针缝合器+手术+32P敷贴组30例。结果①病变厚度≤0.2 cm的患者中,复方倍他米松注射组的治愈率(35.0%)和有效率(55.0%)与单纯32P敷贴组的治愈率(75.0%)和有效率(85.0%)及无针缝合器+32P敷贴组的治愈率(80.0%)与有效率(90.0%)比较差异均有统计学意义(P<0.05);②病变厚度>0.2 cm的患者中,复方倍他米松注射组的治愈率(3.3%)和有效率(23.3%)与其他组比较差异均有统计学意义(P<0.05);单纯32P敷贴组治愈率(20.0%)和有效率(53.3%)与无针缝合器+手术+32P敷贴组的治愈率(86.7%)和有效率(96.7%)及手术+32P敷贴组的治愈率(63.3%)与有效率(90.0%)比较差异均有统计学意义(P<0.05);手术+32P敷贴组的治愈率与无针缝合器+手术+32P敷贴组比较差异有统计学意义(P<0.05)。结论病变厚度≤0.2 cm的患者,可以单纯行32P敷贴治疗;病变厚度>0.2 cm的患者,建议手术切除后给予32P敷贴并结合使用无针缝合器治疗,效果较好。
Objective To investigate the clinical efficacy of ^32P applicator combined with needleless skin instrument for treating chest keloid. Methods Of all the 180 chest keloid patients, 60 with lesion thickness ≤0.2 cm were randomly divided into three groups： 20 received compound betamethasone injection therapy, 20 received ^32P applicator therapy, others were treated with ^32P applicator combined with needieless skin instrument. 120 ones with lesion thickness 〉 0.2 cm were randomly divided into four groups ： 30 received compound betamethasone injection therapy, 30 received ^32P applicator therapy, 30 received operation combined with ^32P applicator therapy, others were treated with operation combined with ^32P applicator and needleless skin instrument. Results ① The cure rate and effective rate in the com- pound betamethasone injection group were 35.0% and 55.0%, which were significantly lower than those （75.0%, 85.0% ）in the simple ^32P application group and （80.0%, 90.0% ）in the ^32P applicator combined with needleless skin instrument group（P 〈 0.05） ; ② The cure rate and effective rate in the compound betamethasone injection group were 3.3 % and 23.3 %, which were significantly lower than those in the other groups （ P 〈 0.05 ） ; The cure rate and effec- tive rate in the simple ^32P application group were 20.0% and 53.3%, which were significantly lower than those （86.7%, 96.7% ） in the operation combined with ^32P applicator and needleless skin instrument group and （63.3,90.0% ） in the operation combined with ^32P applicator group（ P 〈 0.05 ） ; The cure rate in the operation combined with ^32P applicator and needleless skin instrument group was significantly higher than that in the operation combined with ^32P applicator group （P 〈 0.05）. Conclusion For patients with lesion thickness ≤0.2 cm, ^32P applicator therapy only is enough. Otherwise, patients are suggested to use operation combined with 32p applicator and needleless skin instrument therapy.
出处
《山东大学学报（医学版）》
CAS
北大核心
2013年第1期88-92,共5页
Journal of Shandong University:Health Sciences
关键词
无针缝合器
32P敷贴
瘢痕疙瘩
复方倍他米松
张力
Needleless skin instrument
^32P applicator
Keloid
Compound betamethasone
Tension
