The growing prevalence of exercise-induced tibial stress fractures demands wearable sensors capable of monitoring dynamic musculoskeletal loads with medical-grade precision.While flexible pressure-sensing insoles show...The growing prevalence of exercise-induced tibial stress fractures demands wearable sensors capable of monitoring dynamic musculoskeletal loads with medical-grade precision.While flexible pressure-sensing insoles show clinical potential,their development has been hindered by the intrinsic trade-off between high sensitivity and full-range linearity(R^(2)>0.99 up to 1 MPa)in conventional designs.Inspired by the tactile sensing mechanism of human skin,where dermal stratification enables wide-range pressure adaptation and ion-channelregulated signaling maintains linear electrical responses,we developed a dual-mechanism flexible iontronic pressure sensor(FIPS).This innovative design synergistically combines two bioinspired components:interdigitated fabric microstructures enabling pressure-proportional contact area expansion(αP1/3)and iontronic film facilitating self-adaptive ion concentration modulation(αP^(2/3)),which together generate a linear capacitance-pressure response(CαP).The FIPS achieves breakthrough performance:242 kPa^(-1)sensitivity with 0.997linearity across 0-1 MPa,yielding a record linear sensing factor(LSF=242,000).The design is validated across various substrates and ionic materials,demonstrating its versatility.Finally,the FIPS-driven design enables a smart insole demonstrating 1.8%error in tibial load assessment during gait analysis,outperforming nonlinear counterparts(6.5%error)in early fracture-risk prediction.The biomimetic design framework establishes a universal approach for developing high-performance linear sensors,establishing generalized principles for medical-grade wearable devices.展开更多
During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive...During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length.展开更多
AIM:To evaluate long-term visual field(VF)prediction using K-means clustering in patients with primary open angle glaucoma(POAG).METHODS:Patients who underwent 24-2 VF tests≥10 were included in this study.Using 52 to...AIM:To evaluate long-term visual field(VF)prediction using K-means clustering in patients with primary open angle glaucoma(POAG).METHODS:Patients who underwent 24-2 VF tests≥10 were included in this study.Using 52 total deviation values(TDVs)from the first 10 VF tests of the training dataset,VF points were clustered into several regions using the hierarchical ordered partitioning and collapsing hybrid(HOPACH)and K-means clustering.Based on the clustering results,a linear regression analysis was applied to each clustered region of the testing dataset to predict the TDVs of the 10th VF test.Three to nine VF tests were used to predict the 10th VF test,and the prediction errors(root mean square error,RMSE)of each clustering method and pointwise linear regression(PLR)were compared.RESULTS:The training group consisted of 228 patients(mean age,54.20±14.38y;123 males and 105 females),and the testing group included 81 patients(mean age,54.88±15.22y;43 males and 38 females).All subjects were diagnosed with POAG.Fifty-two VF points were clustered into 11 and nine regions using HOPACH and K-means clustering,respectively.K-means clustering had a lower prediction error than PLR when n=1:3 and 1:4(both P≤0.003).The prediction errors of K-means clustering were lower than those of HOPACH in all sections(n=1:4 to 1:9;all P≤0.011),except for n=1:3(P=0.680).PLR outperformed K-means clustering only when n=1:8 and 1:9(both P≤0.020).CONCLUSION:K-means clustering can predict longterm VF test results more accurately in patients with POAG with limited VF data.展开更多
Pyrrolizidine alkaloids(PAs)and their N-oxides(PANOs)are phytotoxins produced by various plant species and have been emerged as environmental pollutants.The sorption/desorption behaviors of PAs/PANOs in soil are cruci...Pyrrolizidine alkaloids(PAs)and their N-oxides(PANOs)are phytotoxins produced by various plant species and have been emerged as environmental pollutants.The sorption/desorption behaviors of PAs/PANOs in soil are crucial due to the horizontal transfer of these natural products from PA-producing plants to soil and subsequently absorbed by plant roots.This study firstly investigated the sorption/desorption behaviors of PAs/PANOs in tea plantation soils with distinct characteristics.Sorption amounts for seneciphylline(Sp)and seneciphylline-N-oxide(SpNO)in three acidic soils ranged from 2.9 to 5.9μg/g and 1.7 to 2.8μg/g,respectively.Desorption percentages for Sp and SpNO were from 22.2%to 30.5%and 36.1%to 43.9%.In the mixed PAs/PANOs systems,stronger sorption of PAs over PANOs was occurred in tested soils.Additionally,the Freundlich models more precisely described the sorption/desorption isotherms.Cation exchange capacity,sand content and total nitrogen were identified as major influencing factors by linear regression models.Overall,the soils exhibiting higher sorption capacities for compounds with greater hydrophobicity.PANOs were more likely to migrate within soils and be absorbed by tea plants.It contributes to the understanding of environmental fate of PAs/PANOs in tea plantations and provides basic data and clues for the development of PAs/PANOs reduction technology.展开更多
GH4169 joints manufactured by Linear Friction Welding(LFW)are subjected to tensile test and stair-case method to evaluate the High Cycle Fatigue(HCF)performance at 650℃.The yield and ultimate tensile strengths are 58...GH4169 joints manufactured by Linear Friction Welding(LFW)are subjected to tensile test and stair-case method to evaluate the High Cycle Fatigue(HCF)performance at 650℃.The yield and ultimate tensile strengths are 582 MPa and 820 MPa,respectively.The HCF strength of joint reaches 400 MPa,which is slightly lower than that of Base Metal(BM),indicating reliable quality of this type of joint.The microstructure observation results show that all cracks initiate at the inside of specimens and transfer into deeper region with decrease of external stress,and the crack initiation site is related with microhardness of matrix.The Electron Backscattered Diffraction(EBSD)results of the observed regions with different distances to fracture show that plastic deformation plays a key role in HCF,and the Schmid factor of most grains near fracture exceeds 0.4.In addition,the generation of twins plays a vital role in strain concentration release and coordinating plastic deformation among grains.展开更多
A two-way K/Ka-band series-Doherty PA(SDPA)with a distributed impedance inverting network(IIN)for millimeter wave applications is presented in this article.The proposed distributed IIN contributes to achieve wideband ...A two-way K/Ka-band series-Doherty PA(SDPA)with a distributed impedance inverting network(IIN)for millimeter wave applications is presented in this article.The proposed distributed IIN contributes to achieve wideband linear and power back-off(PBO)efficiency enhancement.Implemented in 65 nm bulk CMOS technology,this work realizes a measured 3 dB band-width of 15.5 GHz with 21.2 dB peak small-signal gain at 34.2 GHz.Under 1-V power supply,it achieves OP1dB over 13.4 dBm and Psat over 16 dBm between 21 to 30 GHz.The measured maximum Psat,OP1dB,peak/OP1dB/6dBPBO PAE results are 17.5,14.7 dBm,and 28.2%/23.2%/13.2%.Without digital pre-distortion(DPD)and equalization,EVMs are lower than-25.2 dB for 200 MHz 64-QAM signals.Besides,this work achieves-33.35,-23.52,and-20 dB EVMs for 100 MHz 256-QAM,600 MHz 64-QAM and 2 GHz 16-QAM signals at 27 GHz without DPD and equalization.展开更多
Phenotypic prediction is a promising strategy for accelerating plant breeding.Data from multiple sources(called multi-view data)can provide complementary information to characterize a biological object from various as...Phenotypic prediction is a promising strategy for accelerating plant breeding.Data from multiple sources(called multi-view data)can provide complementary information to characterize a biological object from various aspects.By integrating multi-view information into phenotypic prediction,a multi-view best linear unbiased prediction(MVBLUP)method is proposed in this paper.To measure the importance of multiple data views,the differential evolution algorithm with an early stopping mechanism is used,by which we obtain a multi-view kinship matrix and then incorporate it into the BLUP model for phenotypic prediction.To further illustrate the characteristics of MVBLUP,we perform the empirical experiments on four multi-view datasets in different crops.Compared to the single-view method,the prediction accuracy of the MVBLUP method has improved by 0.038–0.201 on average.The results demonstrate that the MVBLUP is an effective integrative prediction method for multi-view data.展开更多
Over the past decades,the expansion of natu-ral secondary forests has played a crucial role in offsetting the loss of primary forests and combating climate change.Despite this,there is a gap in our understanding of ho...Over the past decades,the expansion of natu-ral secondary forests has played a crucial role in offsetting the loss of primary forests and combating climate change.Despite this,there is a gap in our understanding of how tree species’growth and mortality patterns vary with eleva-tion in these secondary forests.In this study,we analyzed data from two censuses(spanning a five-year interval)conducted in both evergreen broadleaved forests(EBF)and temperate coniferous forests(TCF),which have been recovering for half a century,across elevation gradients in a subtropical mountain region,Mount Wuyi,China.The results indicated that the relative growth rate(RGR)of EBF(0.028±0.001 cm·cm^(-1)·a^(-1))and the mortality rate(MR)(20.03%±1.70%)were 27.3%and 16.4%higher,respec-tively,than those of TCF.Interestingly,the trade-off between RGR and MR in EBF weakened as elevation increased,a trend not observed in TCF.Conversely,TCF consistently showed a stronger trade-off between RGR and MR compared to EBF.Generalized linear mixed models revealed that ele-vation influences RGR both directly and indirectly through its interactions with slope,crown competition index(CCI),and tree canopy height(CH).However,tree mortality did not show a significant correlation with elevation.Additionally,DBH significantly influenced both tree growth and mortal-ity,whereas and CH and CCI had opposite effects on tree growth between EBF and TCF.Our study underscores the importance of elevation in shaping the population dynamics and the biomass carbon sink balance of mountain forests.These insights enhance our understanding of tree species’life strategies,enabling more accurate predictions of forest dynamics and their response to environmental changes.展开更多
The pre-weld heat treatment was carried out to obtain different initial microstructures of the GH4169 superalloy,and then Linear Friction Welding(LFW)was performed.The effect of the pre-weld heat treatment on the micr...The pre-weld heat treatment was carried out to obtain different initial microstructures of the GH4169 superalloy,and then Linear Friction Welding(LFW)was performed.The effect of the pre-weld heat treatment on the microstructure evolution and mechanical properties of the joint was analyzed,and the joint electrochemical corrosion behavior as well as the hot corrosion behavior was studied.The results show that the joint hardness of Base Metal(BM)increases after pre-weld heat treatment,and the strengthening phasesγ′andγ″further precipitate.However,the precipitation phases dissolve significantly in the Weld Zone(WZ)due to the thermal process of LFW.The corrosion resistance in BM is reduced after the pre-weld heat treatment,while it is similar in WZ with a slight decrease.The surface morphology of the BM and WZ can be generally divided into a loose and porous matrix and a scattered oxide particle layer after hot corrosion.The joint cross section exhibits a Cr-depleted zone with the diffusion of Cr to form an oxide film.The corrosion product mainly consists of Fe_(2)O_(3)/Fe_(3)O_(4) as the outer layer and Cr_(2)O_(3) as the inner layer.展开更多
The hyperloop idea,which is one of the most ecofriendly,low-carbon emissions,and fossil fuel-efficient modes of transportation,has recently become quite popular.In this study,a double-sided linear induction motor(LIM)...The hyperloop idea,which is one of the most ecofriendly,low-carbon emissions,and fossil fuel-efficient modes of transportation,has recently become quite popular.In this study,a double-sided linear induction motor(LIM)with 500 W of output power,60 N of thrust force and 200 V/38.58 Hz of supply voltage was designed to be used in hyperloop development competition hosted by the scientific and technological research council of turkey(TüB?TAK)rail transportation technologies institute(RUTE).In contrast to the studies in the literature,concentrated winding is preferred instead of distributed winding due to mechanical constraints.The electromagnetic design of LIM,whose mechanical and electrical requirements were determined considering the hyperloop development competition,was carried out by following certain steps.Then,the designed model was simulated and analyzed by finite element method(FEM),and the necessary optimizations have been performed to improve the motor characteristics.By examining the final model,the applicability of the concentrated winding type LIM for hyperloop technology has been investigated.Besides,the effects of primary material,railway material,and mechanical air-gap length on LIM performance were also investigated.In the practical phase of the study,the designed LIM has been prototyped and tested.The validation of the experimental results was achieved through good agreement with the finite element analysis results.展开更多
To examine the effect of bedding angle upon burst proneness in terms of energy,phyllites with seven various bedding angles are selected for conventional uniaxial compression and single-cyclic loading eunloading uniaxi...To examine the effect of bedding angle upon burst proneness in terms of energy,phyllites with seven various bedding angles are selected for conventional uniaxial compression and single-cyclic loading eunloading uniaxial compression tests.The ejection and failure during compression process of phyllites are monitored in real-time by high-speed camera system.The results demonstrate that the phyllites with different bedding angles all consistently follow the linear energy storage and dissipation(LESD)law during compression.The ultimate energy storage of phyllites with varying bedding angles can be calculated precisely via using the LESD law.Based on this,four kinds of energy-based rockburst indices are applied to quantitatively assess the burst proneness for phyllites.Combined with the recorded images of high-speed camera system,ejection distance,and mass of rock fragments and powder,the burst proneness for phyllites with various bedding angles is qualitatively evaluated adopting the far-field ejection mass ratio.Next,burst proneness of anisotropic phyllites is assessed quantitatively and qualitatively.It is found that phyllites with bedding angles of 0°,15°,and 90°have a high burst proneness,and that with bedding angle of 30°has a medium burst proneness,whereas the ones with bedding angles of 45°,60°,and 75°have a low burst proneness.Finally,the published experimental data of shale and sandstone specimens with different bedding angles are extracted,and it is preliminarily verified that the bedding angle does not change the LESD law of rocks.展开更多
Due to the heterogeneity of rock masses and the variability of in situ stress,the traditional linear inversion method is insufficiently accurate to achieve high accuracy of the in situ stress field.To address this cha...Due to the heterogeneity of rock masses and the variability of in situ stress,the traditional linear inversion method is insufficiently accurate to achieve high accuracy of the in situ stress field.To address this challenge,nonlinear stress boundaries for a numerical model are determined through regression analysis of a series of nonlinear coefficient matrices,which are derived from the bubbling method.Considering the randomness and flexibility of the bubbling method,a parametric study is conducted to determine recommended ranges for these parameters,including the standard deviation(σb)of bubble radii,the non-uniform coefficient matrix number(λ)for nonlinear stress boundaries,and the number(m)and positions of in situ stress measurement points.A model case study provides a reference for the selection of these parameters.Additionally,when the nonlinear in situ stress inversion method is employed,stress distortion inevitably occurs near model boundaries,aligning with the Saint Venant's principle.Two strategies are proposed accordingly:employing a systematic reduction of nonlinear coefficients to achieve high inversion accuracy while minimizing significant stress distortion,and excluding regions with severe stress distortion near the model edges while utilizing the central part of the model for subsequent simulations.These two strategies have been successfully implemented in the nonlinear in situ stress inversion of the Xincheng Gold Mine and have achieved higher inversion accuracy than the linear method.Specifically,the linear and nonlinear inversion methods yield root mean square errors(RMSE)of 4.15 and 3.2,and inversion relative errors(δAve)of 22.08%and 17.55%,respectively.Therefore,the nonlinear inversion method outperforms the traditional multiple linear regression method,even in the presence of a systematic reduction in the nonlinear stress boundaries.展开更多
Incremental Nonlinear Dynamic Inversion(INDI)is a control approach that has gained popularity in flight control over the past decade.Besides the INDI law,several common additional components complement an INDI-based c...Incremental Nonlinear Dynamic Inversion(INDI)is a control approach that has gained popularity in flight control over the past decade.Besides the INDI law,several common additional components complement an INDI-based controller.This paper,the second part of a two-part series of surveys on INDI,aims to summarize the modern trends in INDI and its related components.Besides a comprehensive components specification,it addresses their most common challenges,compares different variants,and discusses proposed advances.Further important aspects of INDI are gain design,stability,and robustness.This paper also provides an overview of research conducted concerning these aspects.This paper is written in a tutorial style to familiarize researchers with the essential specifics and pitfalls of INDI and its components.At the same time,it can also serve as a reference for readers already familiar with INDI.展开更多
This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven second...This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven secondary sources,taking as an example ion acceleration by target normal sheath acceleration.The Pearson linear correlation of maximum return current amplitude and proton spectrum cutoff energy is found to be in the range from~0.70 to 0.94.kA-scale return currents rise in all interaction schemes where targets of any kind are charged by escaping laser-accelerated relativistic electrons.Their precise measurement is demonstrated using an inductive scheme that allows operation at high repetition rates.Thus,return currents can be used as a metrological online tool for the optimization of many laser-driven secondary sources and for diagnosing their stability.In particular,in two parametric studies of laser-driven ion acceleration,we carry out a noninvasive online measurement of return currents in a tape target system irradiated by the 1 PW VEGA-3 laser at Centro de Láseres Pulsados:first the size of the irradiated area is varied at best compression of the laser pulse;second,the pulse duration is varied by means of induced group delay dispersion at best focus.This work paves the way to the development of feedback systems that operate at the high repetition rates of PW-class lasers.展开更多
BACKGROUND Chronic hepatitis B often progresses silently toward hepatocellular carcinoma(HCC),a leading cause of mortality worldwide.Early detection of HCC is crucial,yet challenging.AIM To investigate the role of dyn...BACKGROUND Chronic hepatitis B often progresses silently toward hepatocellular carcinoma(HCC),a leading cause of mortality worldwide.Early detection of HCC is crucial,yet challenging.AIM To investigate the role of dynamic changes in alkaline phosphatase to prealbumin ratio(APR)in hepatitis B progression to HCC.METHODS Data from 4843 patients with hepatitis B(January 2015 to January 2024)were analyzed.HCC incidence rates in males and females were compared using the log-rank test.Data were evaluated using Kaplan–Meier analysis.The Linear Mixed-Effects Model was applied to track the fluctuation of APR levels over time.Furthermore,Joint Modeling of Longitudinal and Survival data was employed to investigate the temporal relationship between APR and HCC risk.RESULTS The incidence of HCC was higher in males.To ensure the model’s normality assumption,this study applied a logarithmic transformation to APR,yielding ratio.Ratio levels were higher in females(t=5.26,P<0.01).A 1-unit increase in ratio correlated with a 2.005-fold higher risk of HCC in males(95%CI:1.653-2.431)and a 2.273-fold higher risk in females(95%CI:1.620-3.190).CONCLUSION Males are more prone to HCC,while females have higher APR levels.Despite no baseline APR link,rising APR indicates a higher HCC risk.展开更多
To further understand the performance of the energy harvesters under the influence of the wind force and the random excitation,this paper investigates the stochastic response of the bio-inspired energy harvesters subj...To further understand the performance of the energy harvesters under the influence of the wind force and the random excitation,this paper investigates the stochastic response of the bio-inspired energy harvesters subjected to Gaussian white noise and galloping excitation,simulating the flapping pattern of a seagull and its interaction with wind force.The equivalent linearization method is utilized to convert the original nonlinear model into the Itôstochastic differential equation by minimizing the mean squared error.Then,the second-order steady-state moments about the displacement,velocity,and voltage are derived by combining the moment analysis theory.The theoretical results are simulated numerically to analyze the stochastic response performance under different noise intensities,wind speeds,stiffness coefficients,and electromechanical coupling coefficients,time domain analysis is also conducted to study the performance of the harvester with different parameters.The results reveal that the mean square displacement and voltage increase with increasing the noise intensity and wind speed,larger absolute values of stiffness coefficient correspond to smaller mean square displacement and voltage,and larger electromechanical coupling coefficients can enhance the mean square voltage.Finally,the influence of wind speed and electromechanical coupling coefficient on the stationary probability density function(SPDF)is investigated,revealing the existence of a bimodal distribution under varying environmental conditions.展开更多
Let a_(1),a_(2),a_(3)be nonzero integers with gcd(a_(1),a_(2),a_(3))=1,and let k be any positive integer,K=max[3,|a_(1)|,|a_(2)|,|a_(3)|,k].Suppose that l_(1),l_(2),l_(3)are integers each coprime to k.Suppose further ...Let a_(1),a_(2),a_(3)be nonzero integers with gcd(a_(1),a_(2),a_(3))=1,and let k be any positive integer,K=max[3,|a_(1)|,|a_(2)|,|a_(3)|,k].Suppose that l_(1),l_(2),l_(3)are integers each coprime to k.Suppose further that b is any integer satisfying some necessary congruent conditions.The solvability of linear equation a_(1)p_(1)+a_(2)p_(2)+a_(3)p_(3)=b(p_(j)=l_(j)(mod k),1≤j≤3)with prime variables pi,p_(2),ps is investigated.It is proved that if ai,a_(2),a_(3)are all positive,then the above equation is solvable whenever b≥K^(25);if a,a_(2),a_(3)are not all of the same sign,then the above equation has a solution p_(1),p_(2),p_(3)satisfying max(p_(1),p_(2),p_(3))≤3|b|+K^(25).展开更多
In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the ...In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the rapid determination of optimal embedding impedance for diodes across a specific bandwidth to achieve maximum efficiency through harmonic balance simulations.By optimizing the linear matching circuit with the optimal embedding impedance,the method effectively segregates the simulation of the linear segments from the nonlinear segments in the frequency multiplier circuit,substantially improving the speed of simulations.The design of on-chip linear matching circuits adopts a modular circuit design strategy,incorporating fixed load resistors to simplify the matching challenge.Utilizing this approach,a 340 GHz frequency doubler was developed and measured.The results demonstrate that,across a bandwidth of 330 GHz to 342 GHz,the efficiency of the doubler remains above 10%,with an input power ranging from 98 mW to 141mW and an output power exceeding 13 mW.Notably,at an input power of 141 mW,a peak output power of 21.8 mW was achieved at 334 GHz,corresponding to an efficiency of 15.8%.展开更多
基金supported by the National Natural Science Foundation of China(NSFC 52175281,52475315)Youth Innovation Promotion Association of CAS(2021382)。
文摘The growing prevalence of exercise-induced tibial stress fractures demands wearable sensors capable of monitoring dynamic musculoskeletal loads with medical-grade precision.While flexible pressure-sensing insoles show clinical potential,their development has been hindered by the intrinsic trade-off between high sensitivity and full-range linearity(R^(2)>0.99 up to 1 MPa)in conventional designs.Inspired by the tactile sensing mechanism of human skin,where dermal stratification enables wide-range pressure adaptation and ion-channelregulated signaling maintains linear electrical responses,we developed a dual-mechanism flexible iontronic pressure sensor(FIPS).This innovative design synergistically combines two bioinspired components:interdigitated fabric microstructures enabling pressure-proportional contact area expansion(αP1/3)and iontronic film facilitating self-adaptive ion concentration modulation(αP^(2/3)),which together generate a linear capacitance-pressure response(CαP).The FIPS achieves breakthrough performance:242 kPa^(-1)sensitivity with 0.997linearity across 0-1 MPa,yielding a record linear sensing factor(LSF=242,000).The design is validated across various substrates and ionic materials,demonstrating its versatility.Finally,the FIPS-driven design enables a smart insole demonstrating 1.8%error in tibial load assessment during gait analysis,outperforming nonlinear counterparts(6.5%error)in early fracture-risk prediction.The biomimetic design framework establishes a universal approach for developing high-performance linear sensors,establishing generalized principles for medical-grade wearable devices.
基金supported by the National Natural Sci‐ence Foundation of China(Grant No.62306325)。
文摘During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length.
基金Supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),the Ministry of Health&Welfare,Republic of Korea(No.RS-2020-KH088726)the Patient-Centered Clinical Research Coordinating Center(PACEN),the Ministry of Health and Welfare,Republic of Korea(No.HC19C0276)the National Research Foundation of Korea(NRF),the Korea Government(MSIT)(No.RS-2023-00247504).
文摘AIM:To evaluate long-term visual field(VF)prediction using K-means clustering in patients with primary open angle glaucoma(POAG).METHODS:Patients who underwent 24-2 VF tests≥10 were included in this study.Using 52 total deviation values(TDVs)from the first 10 VF tests of the training dataset,VF points were clustered into several regions using the hierarchical ordered partitioning and collapsing hybrid(HOPACH)and K-means clustering.Based on the clustering results,a linear regression analysis was applied to each clustered region of the testing dataset to predict the TDVs of the 10th VF test.Three to nine VF tests were used to predict the 10th VF test,and the prediction errors(root mean square error,RMSE)of each clustering method and pointwise linear regression(PLR)were compared.RESULTS:The training group consisted of 228 patients(mean age,54.20±14.38y;123 males and 105 females),and the testing group included 81 patients(mean age,54.88±15.22y;43 males and 38 females).All subjects were diagnosed with POAG.Fifty-two VF points were clustered into 11 and nine regions using HOPACH and K-means clustering,respectively.K-means clustering had a lower prediction error than PLR when n=1:3 and 1:4(both P≤0.003).The prediction errors of K-means clustering were lower than those of HOPACH in all sections(n=1:4 to 1:9;all P≤0.011),except for n=1:3(P=0.680).PLR outperformed K-means clustering only when n=1:8 and 1:9(both P≤0.020).CONCLUSION:K-means clustering can predict longterm VF test results more accurately in patients with POAG with limited VF data.
基金supported by the earmarked fund for the Modern Agro-Industry Technology Research System (No.CARS-19)the Innovative Research Team in Chinese Academy of Agricultural Sciences (No.CAAS ASTIP-2014-TRICAAS).
文摘Pyrrolizidine alkaloids(PAs)and their N-oxides(PANOs)are phytotoxins produced by various plant species and have been emerged as environmental pollutants.The sorption/desorption behaviors of PAs/PANOs in soil are crucial due to the horizontal transfer of these natural products from PA-producing plants to soil and subsequently absorbed by plant roots.This study firstly investigated the sorption/desorption behaviors of PAs/PANOs in tea plantation soils with distinct characteristics.Sorption amounts for seneciphylline(Sp)and seneciphylline-N-oxide(SpNO)in three acidic soils ranged from 2.9 to 5.9μg/g and 1.7 to 2.8μg/g,respectively.Desorption percentages for Sp and SpNO were from 22.2%to 30.5%and 36.1%to 43.9%.In the mixed PAs/PANOs systems,stronger sorption of PAs over PANOs was occurred in tested soils.Additionally,the Freundlich models more precisely described the sorption/desorption isotherms.Cation exchange capacity,sand content and total nitrogen were identified as major influencing factors by linear regression models.Overall,the soils exhibiting higher sorption capacities for compounds with greater hydrophobicity.PANOs were more likely to migrate within soils and be absorbed by tea plants.It contributes to the understanding of environmental fate of PAs/PANOs in tea plantations and provides basic data and clues for the development of PAs/PANOs reduction technology.
基金supported by the National Natural Science Foundation of China(Nos.52074228,52305420,and 51875470)the China Postdoctoral Science Foundation(No.2023M742830)。
文摘GH4169 joints manufactured by Linear Friction Welding(LFW)are subjected to tensile test and stair-case method to evaluate the High Cycle Fatigue(HCF)performance at 650℃.The yield and ultimate tensile strengths are 582 MPa and 820 MPa,respectively.The HCF strength of joint reaches 400 MPa,which is slightly lower than that of Base Metal(BM),indicating reliable quality of this type of joint.The microstructure observation results show that all cracks initiate at the inside of specimens and transfer into deeper region with decrease of external stress,and the crack initiation site is related with microhardness of matrix.The Electron Backscattered Diffraction(EBSD)results of the observed regions with different distances to fracture show that plastic deformation plays a key role in HCF,and the Schmid factor of most grains near fracture exceeds 0.4.In addition,the generation of twins plays a vital role in strain concentration release and coordinating plastic deformation among grains.
基金supported in part by the National Key Research and Development Program of China under Grant 2020YFB1807300the Beijing Advanced Innovation Center for Integrated Circuits。
文摘A two-way K/Ka-band series-Doherty PA(SDPA)with a distributed impedance inverting network(IIN)for millimeter wave applications is presented in this article.The proposed distributed IIN contributes to achieve wideband linear and power back-off(PBO)efficiency enhancement.Implemented in 65 nm bulk CMOS technology,this work realizes a measured 3 dB band-width of 15.5 GHz with 21.2 dB peak small-signal gain at 34.2 GHz.Under 1-V power supply,it achieves OP1dB over 13.4 dBm and Psat over 16 dBm between 21 to 30 GHz.The measured maximum Psat,OP1dB,peak/OP1dB/6dBPBO PAE results are 17.5,14.7 dBm,and 28.2%/23.2%/13.2%.Without digital pre-distortion(DPD)and equalization,EVMs are lower than-25.2 dB for 200 MHz 64-QAM signals.Besides,this work achieves-33.35,-23.52,and-20 dB EVMs for 100 MHz 256-QAM,600 MHz 64-QAM and 2 GHz 16-QAM signals at 27 GHz without DPD and equalization.
基金supported by National Natural Science Foundation of China(32122066,32201855)STI2030—Major Projects(2023ZD04076).
文摘Phenotypic prediction is a promising strategy for accelerating plant breeding.Data from multiple sources(called multi-view data)can provide complementary information to characterize a biological object from various aspects.By integrating multi-view information into phenotypic prediction,a multi-view best linear unbiased prediction(MVBLUP)method is proposed in this paper.To measure the importance of multiple data views,the differential evolution algorithm with an early stopping mechanism is used,by which we obtain a multi-view kinship matrix and then incorporate it into the BLUP model for phenotypic prediction.To further illustrate the characteristics of MVBLUP,we perform the empirical experiments on four multi-view datasets in different crops.Compared to the single-view method,the prediction accuracy of the MVBLUP method has improved by 0.038–0.201 on average.The results demonstrate that the MVBLUP is an effective integrative prediction method for multi-view data.
基金funded by the National Natural Science Foundation of China(Grant No.32271872).
文摘Over the past decades,the expansion of natu-ral secondary forests has played a crucial role in offsetting the loss of primary forests and combating climate change.Despite this,there is a gap in our understanding of how tree species’growth and mortality patterns vary with eleva-tion in these secondary forests.In this study,we analyzed data from two censuses(spanning a five-year interval)conducted in both evergreen broadleaved forests(EBF)and temperate coniferous forests(TCF),which have been recovering for half a century,across elevation gradients in a subtropical mountain region,Mount Wuyi,China.The results indicated that the relative growth rate(RGR)of EBF(0.028±0.001 cm·cm^(-1)·a^(-1))and the mortality rate(MR)(20.03%±1.70%)were 27.3%and 16.4%higher,respec-tively,than those of TCF.Interestingly,the trade-off between RGR and MR in EBF weakened as elevation increased,a trend not observed in TCF.Conversely,TCF consistently showed a stronger trade-off between RGR and MR compared to EBF.Generalized linear mixed models revealed that ele-vation influences RGR both directly and indirectly through its interactions with slope,crown competition index(CCI),and tree canopy height(CH).However,tree mortality did not show a significant correlation with elevation.Additionally,DBH significantly influenced both tree growth and mortal-ity,whereas and CH and CCI had opposite effects on tree growth between EBF and TCF.Our study underscores the importance of elevation in shaping the population dynamics and the biomass carbon sink balance of mountain forests.These insights enhance our understanding of tree species’life strategies,enabling more accurate predictions of forest dynamics and their response to environmental changes.
基金supported by the National Natural Science Foundation of China(Nos.52074228,52305420 and 51875470)the Practice and Innovation Funds for Graduate Students of Northwestern Polytechnical University,China(No.PF2024053)the Xi’an Beilin District Science and Technology Planning Project,China(No.GX2349).
文摘The pre-weld heat treatment was carried out to obtain different initial microstructures of the GH4169 superalloy,and then Linear Friction Welding(LFW)was performed.The effect of the pre-weld heat treatment on the microstructure evolution and mechanical properties of the joint was analyzed,and the joint electrochemical corrosion behavior as well as the hot corrosion behavior was studied.The results show that the joint hardness of Base Metal(BM)increases after pre-weld heat treatment,and the strengthening phasesγ′andγ″further precipitate.However,the precipitation phases dissolve significantly in the Weld Zone(WZ)due to the thermal process of LFW.The corrosion resistance in BM is reduced after the pre-weld heat treatment,while it is similar in WZ with a slight decrease.The surface morphology of the BM and WZ can be generally divided into a loose and porous matrix and a scattered oxide particle layer after hot corrosion.The joint cross section exhibits a Cr-depleted zone with the diffusion of Cr to form an oxide film.The corrosion product mainly consists of Fe_(2)O_(3)/Fe_(3)O_(4) as the outer layer and Cr_(2)O_(3) as the inner layer.
基金the Istanbul Technical University Scientific Research Projects Unit with grant number MGA-2022-43948。
文摘The hyperloop idea,which is one of the most ecofriendly,low-carbon emissions,and fossil fuel-efficient modes of transportation,has recently become quite popular.In this study,a double-sided linear induction motor(LIM)with 500 W of output power,60 N of thrust force and 200 V/38.58 Hz of supply voltage was designed to be used in hyperloop development competition hosted by the scientific and technological research council of turkey(TüB?TAK)rail transportation technologies institute(RUTE).In contrast to the studies in the literature,concentrated winding is preferred instead of distributed winding due to mechanical constraints.The electromagnetic design of LIM,whose mechanical and electrical requirements were determined considering the hyperloop development competition,was carried out by following certain steps.Then,the designed model was simulated and analyzed by finite element method(FEM),and the necessary optimizations have been performed to improve the motor characteristics.By examining the final model,the applicability of the concentrated winding type LIM for hyperloop technology has been investigated.Besides,the effects of primary material,railway material,and mechanical air-gap length on LIM performance were also investigated.In the practical phase of the study,the designed LIM has been prototyped and tested.The validation of the experimental results was achieved through good agreement with the finite element analysis results.
基金supported by the National Natural Science Foundation of China(Grant No.42077244).
文摘To examine the effect of bedding angle upon burst proneness in terms of energy,phyllites with seven various bedding angles are selected for conventional uniaxial compression and single-cyclic loading eunloading uniaxial compression tests.The ejection and failure during compression process of phyllites are monitored in real-time by high-speed camera system.The results demonstrate that the phyllites with different bedding angles all consistently follow the linear energy storage and dissipation(LESD)law during compression.The ultimate energy storage of phyllites with varying bedding angles can be calculated precisely via using the LESD law.Based on this,four kinds of energy-based rockburst indices are applied to quantitatively assess the burst proneness for phyllites.Combined with the recorded images of high-speed camera system,ejection distance,and mass of rock fragments and powder,the burst proneness for phyllites with various bedding angles is qualitatively evaluated adopting the far-field ejection mass ratio.Next,burst proneness of anisotropic phyllites is assessed quantitatively and qualitatively.It is found that phyllites with bedding angles of 0°,15°,and 90°have a high burst proneness,and that with bedding angle of 30°has a medium burst proneness,whereas the ones with bedding angles of 45°,60°,and 75°have a low burst proneness.Finally,the published experimental data of shale and sandstone specimens with different bedding angles are extracted,and it is preliminarily verified that the bedding angle does not change the LESD law of rocks.
基金funded by the National Key R&D Program of China(Grant No.2022YFC2903904)the National Natural Science Foundation of China(Grant Nos.51904057 and U1906208).
文摘Due to the heterogeneity of rock masses and the variability of in situ stress,the traditional linear inversion method is insufficiently accurate to achieve high accuracy of the in situ stress field.To address this challenge,nonlinear stress boundaries for a numerical model are determined through regression analysis of a series of nonlinear coefficient matrices,which are derived from the bubbling method.Considering the randomness and flexibility of the bubbling method,a parametric study is conducted to determine recommended ranges for these parameters,including the standard deviation(σb)of bubble radii,the non-uniform coefficient matrix number(λ)for nonlinear stress boundaries,and the number(m)and positions of in situ stress measurement points.A model case study provides a reference for the selection of these parameters.Additionally,when the nonlinear in situ stress inversion method is employed,stress distortion inevitably occurs near model boundaries,aligning with the Saint Venant's principle.Two strategies are proposed accordingly:employing a systematic reduction of nonlinear coefficients to achieve high inversion accuracy while minimizing significant stress distortion,and excluding regions with severe stress distortion near the model edges while utilizing the central part of the model for subsequent simulations.These two strategies have been successfully implemented in the nonlinear in situ stress inversion of the Xincheng Gold Mine and have achieved higher inversion accuracy than the linear method.Specifically,the linear and nonlinear inversion methods yield root mean square errors(RMSE)of 4.15 and 3.2,and inversion relative errors(δAve)of 22.08%and 17.55%,respectively.Therefore,the nonlinear inversion method outperforms the traditional multiple linear regression method,even in the presence of a systematic reduction in the nonlinear stress boundaries.
文摘Incremental Nonlinear Dynamic Inversion(INDI)is a control approach that has gained popularity in flight control over the past decade.Besides the INDI law,several common additional components complement an INDI-based controller.This paper,the second part of a two-part series of surveys on INDI,aims to summarize the modern trends in INDI and its related components.Besides a comprehensive components specification,it addresses their most common challenges,compares different variants,and discusses proposed advances.Further important aspects of INDI are gain design,stability,and robustness.This paper also provides an overview of research conducted concerning these aspects.This paper is written in a tutorial style to familiarize researchers with the essential specifics and pitfalls of INDI and its components.At the same time,it can also serve as a reference for readers already familiar with INDI.
基金funding from the European Union’s Horizon 2020 research and innovation program through the European IMPULSE project under Grant Agreement No.871161from LASERLAB-EUROPE V under Grant Agreement No.871124+6 种基金from the Grant Agency of the Czech Republic(Grant No.GM23-05027M)Grant No.PDC2021120933-I00 funded by MCIN/AEI/10.13039/501100011033by the European Union Next Generation EU/PRTRsupported by funding from the Ministerio de Ciencia,Innovación y Universidades in Spain through ICTS Equipment Grant No.EQC2018-005230-Pfrom Grant No.PID2021-125389O A-I00 funded by MCIN/AEI/10.13039/501100011033/FEDER,UEby“ERDF A Way of Making Europe”by the European Unionfrom grants of the Junta de Castilla y León with Grant Nos.CLP263P20 and CLP087U16。
文摘This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven secondary sources,taking as an example ion acceleration by target normal sheath acceleration.The Pearson linear correlation of maximum return current amplitude and proton spectrum cutoff energy is found to be in the range from~0.70 to 0.94.kA-scale return currents rise in all interaction schemes where targets of any kind are charged by escaping laser-accelerated relativistic electrons.Their precise measurement is demonstrated using an inductive scheme that allows operation at high repetition rates.Thus,return currents can be used as a metrological online tool for the optimization of many laser-driven secondary sources and for diagnosing their stability.In particular,in two parametric studies of laser-driven ion acceleration,we carry out a noninvasive online measurement of return currents in a tape target system irradiated by the 1 PW VEGA-3 laser at Centro de Láseres Pulsados:first the size of the irradiated area is varied at best compression of the laser pulse;second,the pulse duration is varied by means of induced group delay dispersion at best focus.This work paves the way to the development of feedback systems that operate at the high repetition rates of PW-class lasers.
文摘BACKGROUND Chronic hepatitis B often progresses silently toward hepatocellular carcinoma(HCC),a leading cause of mortality worldwide.Early detection of HCC is crucial,yet challenging.AIM To investigate the role of dynamic changes in alkaline phosphatase to prealbumin ratio(APR)in hepatitis B progression to HCC.METHODS Data from 4843 patients with hepatitis B(January 2015 to January 2024)were analyzed.HCC incidence rates in males and females were compared using the log-rank test.Data were evaluated using Kaplan–Meier analysis.The Linear Mixed-Effects Model was applied to track the fluctuation of APR levels over time.Furthermore,Joint Modeling of Longitudinal and Survival data was employed to investigate the temporal relationship between APR and HCC risk.RESULTS The incidence of HCC was higher in males.To ensure the model’s normality assumption,this study applied a logarithmic transformation to APR,yielding ratio.Ratio levels were higher in females(t=5.26,P<0.01).A 1-unit increase in ratio correlated with a 2.005-fold higher risk of HCC in males(95%CI:1.653-2.431)and a 2.273-fold higher risk in females(95%CI:1.620-3.190).CONCLUSION Males are more prone to HCC,while females have higher APR levels.Despite no baseline APR link,rising APR indicates a higher HCC risk.
文摘To further understand the performance of the energy harvesters under the influence of the wind force and the random excitation,this paper investigates the stochastic response of the bio-inspired energy harvesters subjected to Gaussian white noise and galloping excitation,simulating the flapping pattern of a seagull and its interaction with wind force.The equivalent linearization method is utilized to convert the original nonlinear model into the Itôstochastic differential equation by minimizing the mean squared error.Then,the second-order steady-state moments about the displacement,velocity,and voltage are derived by combining the moment analysis theory.The theoretical results are simulated numerically to analyze the stochastic response performance under different noise intensities,wind speeds,stiffness coefficients,and electromechanical coupling coefficients,time domain analysis is also conducted to study the performance of the harvester with different parameters.The results reveal that the mean square displacement and voltage increase with increasing the noise intensity and wind speed,larger absolute values of stiffness coefficient correspond to smaller mean square displacement and voltage,and larger electromechanical coupling coefficients can enhance the mean square voltage.Finally,the influence of wind speed and electromechanical coupling coefficient on the stationary probability density function(SPDF)is investigated,revealing the existence of a bimodal distribution under varying environmental conditions.
文摘Let a_(1),a_(2),a_(3)be nonzero integers with gcd(a_(1),a_(2),a_(3))=1,and let k be any positive integer,K=max[3,|a_(1)|,|a_(2)|,|a_(3)|,k].Suppose that l_(1),l_(2),l_(3)are integers each coprime to k.Suppose further that b is any integer satisfying some necessary congruent conditions.The solvability of linear equation a_(1)p_(1)+a_(2)p_(2)+a_(3)p_(3)=b(p_(j)=l_(j)(mod k),1≤j≤3)with prime variables pi,p_(2),ps is investigated.It is proved that if ai,a_(2),a_(3)are all positive,then the above equation is solvable whenever b≥K^(25);if a,a_(2),a_(3)are not all of the same sign,then the above equation has a solution p_(1),p_(2),p_(3)satisfying max(p_(1),p_(2),p_(3))≤3|b|+K^(25).
基金Supported by the Beijing Municipal Science&Technology Commission(Z211100004421012),the Key Reaserch and Development Pro⁃gram of China(2022YFF0605902)。
文摘In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the rapid determination of optimal embedding impedance for diodes across a specific bandwidth to achieve maximum efficiency through harmonic balance simulations.By optimizing the linear matching circuit with the optimal embedding impedance,the method effectively segregates the simulation of the linear segments from the nonlinear segments in the frequency multiplier circuit,substantially improving the speed of simulations.The design of on-chip linear matching circuits adopts a modular circuit design strategy,incorporating fixed load resistors to simplify the matching challenge.Utilizing this approach,a 340 GHz frequency doubler was developed and measured.The results demonstrate that,across a bandwidth of 330 GHz to 342 GHz,the efficiency of the doubler remains above 10%,with an input power ranging from 98 mW to 141mW and an output power exceeding 13 mW.Notably,at an input power of 141 mW,a peak output power of 21.8 mW was achieved at 334 GHz,corresponding to an efficiency of 15.8%.
