本文介绍一种新型的位置读出方法,用于开发高分辨的小型伽玛相机。该伽玛相机采用小单元的CsI(Na)晶体阵列与位置灵敏光电倍增管(PSPMT)结合的探测器。其位置读出电路的设计把常规的阻抗电荷分配法与多路单通道直接读出法的优点结合在一...本文介绍一种新型的位置读出方法,用于开发高分辨的小型伽玛相机。该伽玛相机采用小单元的CsI(Na)晶体阵列与位置灵敏光电倍增管(PSPMT)结合的探测器。其位置读出电路的设计把常规的阻抗电荷分配法与多路单通道直接读出法的优点结合在一起,由硬件实现局域重心法(Truncated center of gravity)计算读出的位置,取得很好的效果。该伽玛相机的内在分辨率接近1mm,视野(FOV)达探测器的灵敏范围。这种新型的位置读出方法也可用于更高集成度的多阳极的位置灵敏光电倍增管的位置读出。展开更多
The performance of gamma camera with NaI(Tl) array coupled with position sensitive photomultiplier tube (PSPMT) R2486 has been studied. The pixel size of NaI(Tl) crystal is 2mm×2mm and the overall dimension of th...The performance of gamma camera with NaI(Tl) array coupled with position sensitive photomultiplier tube (PSPMT) R2486 has been studied. The pixel size of NaI(Tl) crystal is 2mm×2mm and the overall dimension of the array is 48.2mm×48.2mm×5mm. There are 484 pixels in a 22×22 matrix. Because each pixel can produce a much focused light spot and restrict the spread of photons, position resolution of the gamma camera is mainly determined by pixel size. It is shown that crystal array pixel can reduce shrinkage effect and improve intrinsic position resolution greatly via restricting the spread of photons. Experimental results demonstrate that its position resolution and linearity are much improved comparing with the gamma camera using planar crystals coupled with PSPMT.展开更多
A new signal readout method for position-sensitive multi-output detectors,such as those in high-energy spectroscopy measurement and nuclear imaging,was developed by combining the charge division circuit,summing circui...A new signal readout method for position-sensitive multi-output detectors,such as those in high-energy spectroscopy measurement and nuclear imaging,was developed by combining the charge division circuit,summing circuit and charge-to-time conversion(QTC) circuit.The 64 outputs of a Hamamatsu H8500 position-sensitive photomultiplier tube were processed,and three digital pulses were generated.The widths of digital pulses were determined using the time-to-digital converter in an field programmable gate array.The energy and position information of incident y-rays is estimated based on the proportionality between the width of digital pulses and input charge created by y-photons.A prototype was built using discrete components and tested,and the energy and position resolutions were improved compared with that obtained with standard ADCs.This method greatly simplifies the front-end electronics and the digital interface.It enables a compact electronics system and an easy integration into an ASIC.展开更多
A compact gamma-ray detector with good spatial resolution for emission computed tomography (E-CT) applications has been developed. The detector is composed of NaI(Tl) scintillation pixels array and Hamamastu R2486-05 ...A compact gamma-ray detector with good spatial resolution for emission computed tomography (E-CT) applications has been developed. The detector is composed of NaI(Tl) scintillation pixels array and Hamamastu R2486-05 PSPMT. Having a pixel size of 2 mm × 2 mm and an overall dimension of 48.2 mm × 48.2mm × 5 mm, it has 484 pixels in a 22×22 matrix. An average spatial resolution of 2.5mm (FWHM) was achieved. The slope of position linearity is constant within 10% in a range of 40mm. After corrections, the average value of differential non-linearity and absolute non-linearity were 0.16mm and 0.535mm respectively, and a 17% at FWHM of total energy resolution for 241Am was obtained.展开更多
A new compact gamma camera for small object imaging has been developed.It consists of a pixelized Nal(T1) scintillator array coupled to a position sensitive photomultiplier tube (Hamamatsu R2486) with a parallel-hole ...A new compact gamma camera for small object imaging has been developed.It consists of a pixelized Nal(T1) scintillator array coupled to a position sensitive photomultiplier tube (Hamamatsu R2486) with a parallel-hole lead collimator.The compact camera has better spatial resolution than Anger camera.The average value of intrinsic spatial resolutions is 2.3 mm (FWHM).The overall spatial resolution (FWHM) is 3,5 and 6 mm at 0,2.5 and 3 mm SCD (source-to-collimator distance),respectively.The phantom studies with the compact camera have demonstrated that parallel-hole collimator gamma camera is a practical technique for nuclear medicine application.展开更多
Dedicated position sensitive gamma-ray detectors based on position sensitive photomultiplier tubes （PSPMTs） coupled to scintillation crystals, have been used for the construction of compact gamma-ray imaging systems...Dedicated position sensitive gamma-ray detectors based on position sensitive photomultiplier tubes （PSPMTs） coupled to scintillation crystals, have been used for the construction of compact gamma-ray imaging systems, suitable for nuclear medical imaging applications such as small animal imaging and single organ imaging and scintimammography. In this work, the performance of two gamma-ray detectors： a continuous YAP scintillation crystal coupled to a Harnamastu R2486 PSPMT and a pixellated NaI（TI） scintillation array crystal coupled to the same PSPMT, is compared. The results show that the gamma-ray detector based on a pixellated NaI（TI） scintillation array crystal is a promising candidate for nuclear medical imaging applications, since their performance in terms of position linearity, spatial resolution and effective field of view （FOV） is superior than that of the gamma-ray detector based on a continuous YAP scintillation crystal. However, a better photodetector （Hamamatau H8500 Flat Panel PMT, for example） coupled to the continuous crystal is also likely a good selection for nuclear medicine imaging applications.展开更多
文摘本文介绍一种新型的位置读出方法,用于开发高分辨的小型伽玛相机。该伽玛相机采用小单元的CsI(Na)晶体阵列与位置灵敏光电倍增管(PSPMT)结合的探测器。其位置读出电路的设计把常规的阻抗电荷分配法与多路单通道直接读出法的优点结合在一起,由硬件实现局域重心法(Truncated center of gravity)计算读出的位置,取得很好的效果。该伽玛相机的内在分辨率接近1mm,视野(FOV)达探测器的灵敏范围。这种新型的位置读出方法也可用于更高集成度的多阳极的位置灵敏光电倍增管的位置读出。
基金Supported by National Foundation of Natural Sciences of China (10275063)
文摘The performance of gamma camera with NaI(Tl) array coupled with position sensitive photomultiplier tube (PSPMT) R2486 has been studied. The pixel size of NaI(Tl) crystal is 2mm×2mm and the overall dimension of the array is 48.2mm×48.2mm×5mm. There are 484 pixels in a 22×22 matrix. Because each pixel can produce a much focused light spot and restrict the spread of photons, position resolution of the gamma camera is mainly determined by pixel size. It is shown that crystal array pixel can reduce shrinkage effect and improve intrinsic position resolution greatly via restricting the spread of photons. Experimental results demonstrate that its position resolution and linearity are much improved comparing with the gamma camera using planar crystals coupled with PSPMT.
基金supported by the National Key Scientific Instrument and Equipment Development Project(No.2011YQ120096)National Instrumentation Program(No.2013YQ030629)the National Natural Science Foundation of China(Nos.11475206,11175200 and11205170)
文摘A new signal readout method for position-sensitive multi-output detectors,such as those in high-energy spectroscopy measurement and nuclear imaging,was developed by combining the charge division circuit,summing circuit and charge-to-time conversion(QTC) circuit.The 64 outputs of a Hamamatsu H8500 position-sensitive photomultiplier tube were processed,and three digital pulses were generated.The widths of digital pulses were determined using the time-to-digital converter in an field programmable gate array.The energy and position information of incident y-rays is estimated based on the proportionality between the width of digital pulses and input charge created by y-photons.A prototype was built using discrete components and tested,and the energy and position resolutions were improved compared with that obtained with standard ADCs.This method greatly simplifies the front-end electronics and the digital interface.It enables a compact electronics system and an easy integration into an ASIC.
基金National Natural Science Foundation of China (No.10275063)
文摘A compact gamma-ray detector with good spatial resolution for emission computed tomography (E-CT) applications has been developed. The detector is composed of NaI(Tl) scintillation pixels array and Hamamastu R2486-05 PSPMT. Having a pixel size of 2 mm × 2 mm and an overall dimension of 48.2 mm × 48.2mm × 5 mm, it has 484 pixels in a 22×22 matrix. An average spatial resolution of 2.5mm (FWHM) was achieved. The slope of position linearity is constant within 10% in a range of 40mm. After corrections, the average value of differential non-linearity and absolute non-linearity were 0.16mm and 0.535mm respectively, and a 17% at FWHM of total energy resolution for 241Am was obtained.
基金Supported by National Natural Science Foundation of China (No.10275063)
文摘A new compact gamma camera for small object imaging has been developed.It consists of a pixelized Nal(T1) scintillator array coupled to a position sensitive photomultiplier tube (Hamamatsu R2486) with a parallel-hole lead collimator.The compact camera has better spatial resolution than Anger camera.The average value of intrinsic spatial resolutions is 2.3 mm (FWHM).The overall spatial resolution (FWHM) is 3,5 and 6 mm at 0,2.5 and 3 mm SCD (source-to-collimator distance),respectively.The phantom studies with the compact camera have demonstrated that parallel-hole collimator gamma camera is a practical technique for nuclear medicine application.
基金Supported by National Nature Science Foundation of China (10275063)
文摘Dedicated position sensitive gamma-ray detectors based on position sensitive photomultiplier tubes （PSPMTs） coupled to scintillation crystals, have been used for the construction of compact gamma-ray imaging systems, suitable for nuclear medical imaging applications such as small animal imaging and single organ imaging and scintimammography. In this work, the performance of two gamma-ray detectors： a continuous YAP scintillation crystal coupled to a Harnamastu R2486 PSPMT and a pixellated NaI（TI） scintillation array crystal coupled to the same PSPMT, is compared. The results show that the gamma-ray detector based on a pixellated NaI（TI） scintillation array crystal is a promising candidate for nuclear medical imaging applications, since their performance in terms of position linearity, spatial resolution and effective field of view （FOV） is superior than that of the gamma-ray detector based on a continuous YAP scintillation crystal. However, a better photodetector （Hamamatau H8500 Flat Panel PMT, for example） coupled to the continuous crystal is also likely a good selection for nuclear medicine imaging applications.
