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An Unusual Case of Sternoclavicular Joint Infection and Lung Abscess 被引量:1
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作者 Carina Rolo Silvestre Ricardo Cordeiro +4 位作者 Daniel Duarte Hugo Ferreira Carla Cardoso Teresa Falcao António Domingos 《Open Journal of Respiratory Diseases》 2020年第2期43-48,共6页
Septic arthritis of the sternoclavicular joint is a rare and serious infection. A delay in the diagnosis may lead to serious complications. The appropriate medical and surgical treatment is crucial to the outcome. Thi... Septic arthritis of the sternoclavicular joint is a rare and serious infection. A delay in the diagnosis may lead to serious complications. The appropriate medical and surgical treatment is crucial to the outcome. This article aims to report our experience in the successful management of sternoclavicular joint infection complicated with a lung infection. The authors present an unusual case of sternoclavicular joint infection extending into lung parenchyma with lung abscess formation in a diabetic patient, with uncontrolled diabetes that was successfully treated. At revaluation, he was asymptomatic with no evidence of relapse. Although sternoclavicular joint infection is a rare condition we highlight the importance of clinician’s awareness for an early diagnosis and treatment with broad-spectrum antibiotics and surgery. 展开更多
关键词 lung abscess Septic Arthritis Sternoclavicular Joint Diabetes Mellitus
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A CASE OF TRICUSPID ENDOCARDITIS WITH SUBSEQUENT LUNG ABSCESS
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作者 Hou-li Wang Yi Li Teng-da Xu 《Chinese Medical Sciences Journal》 CAS CSCD 2007年第2期136-138,共3页
THE incidence of isolated right heart infective endocarditis (IE) is far less common than that of left heart. Clinical presentation is often associated with pulmonary manifestations. The main symptoms include high f... THE incidence of isolated right heart infective endocarditis (IE) is far less common than that of left heart. Clinical presentation is often associated with pulmonary manifestations. The main symptoms include high fever, chest pain, and dyspnea due to septic pulmonary emboli. Degenerative valvular disease, congenital heart diseases, prosthetic valves, long-term hemodialysis, diabetes mellitus predispose patients at increased risk of IE.1 In young persons, IE may be associated with intravenous drug abuse.2 This report dealt with a young patient who had none of the risk factors mentioned above. He was diagnosed and treated for lung abscess and septemia for one and a half months. Further investigation unveiled infective vegetation on tricuspid valve. Following surgical resection of the vegetation, fever and respiratory symptoms completely remitted. The mechanism of the IE occurred on the normal native tricuspid valve is proposed. 展开更多
关键词 infective endocarditis right heart endocarditis lung abscess EMERGENCY
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Idiopathic colopleural fistula presenting with lung abscess and refractory empyema:A case report
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作者 Chun-Li Wang Kung-Chuan Cheng 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第4期740-744,共5页
BACKGROUND Colopleural fistula is a rare condition,and only a limited number of cases have been reported.Here,we report a case of idiopathic colopleural fistula in an adult without any known predisposing factors.The p... BACKGROUND Colopleural fistula is a rare condition,and only a limited number of cases have been reported.Here,we report a case of idiopathic colopleural fistula in an adult without any known predisposing factors.The patient presented with a lung abscess and refractory empyema and was successfully treated with surgical resection.CASE SUMMARY A 47-year-old man with a history of lung tuberculosis,which had been completely cured 4 years ago,presented to our emergency department with a productive cough and fever for 3 d.Tracing his history,he had undergone left lower lobe segmentectomy of the left lung due to lung abscess one year ago at another hospital.However,he developed refractory empyema postoperatively despite surgical intervention including decortication and flap reconstruction.After admission,we reviewed his previous medical images and noted a fistula tract between the left pleural cavity and splenic flexure.In addition,according to his medical records,bacterial culture of the thoracic drainage showed growth of Escherichia coli and Bacteroides fragilis.Our lower gastrointestinal series and colonoscopy confirmed the diagnosis of colopleural fistula.The patient underwent a left hemicolectomy,splenectomy,and distal pancreatectomy,and the diaphragm was repaired under our care.No further empyema recurrence was noted during follow-up.CONCLUSION Indicative signs of colopleural fistula include refractory empyema accompanied by the growth of colonic flora in the pleural fluid. 展开更多
关键词 Colopleural fistula lung abscess EMPYEMA Colonic flora Case report
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Evaluation of the Effect of Nursing Intervention on Lung Abscess Patients
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作者 YANG Yaru 《外文科技期刊数据库(文摘版)医药卫生》 2021年第9期787-788,共3页
Objective: to analyze the effect of nursing intervention on lung abscess patients. Methods: the study object is 90 cases of lung abscess, the author used the average grouping method to divide the selected 90 patients ... Objective: to analyze the effect of nursing intervention on lung abscess patients. Methods: the study object is 90 cases of lung abscess, the author used the average grouping method to divide the selected 90 patients into 2 groups, a group to take routine nursing, set as the reference group, another group to implement high-quality nursing, set as the experimental group, and compare the nursing outcomes of the two groups. Results: the clinical efficacy and nursing satisfaction of the experimental group were better than that of the reference group (P<0.05). Conclusion: high-quality nursing intervention can improve the therapeutic effect of lung abscess patients, make patients disappear as soon as possible, make patients recover as soon as possible, this nursing mode is highly recognized by patients, is worth recommending. 展开更多
关键词 quality nursing lung abscess. therapeutic effect clinical value
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Covert lung abscess as a cause of atrial arrhythmia: case report 被引量:1
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作者 LIMei LIAODe-ning +2 位作者 ZHANGJia-you YINRen-fu WUZong-gui 《Chinese Medical Journal》 SCIE CAS CSCD 2005年第14期1227-1229,共3页
Atrial arrhythmia is common in clinic. Recently, it was revealed that ectopicimpulses originating in sleeve muscles around the orifices of pulmonary veins (PVs) were deemed tobe one of the most important reasons that ... Atrial arrhythmia is common in clinic. Recently, it was revealed that ectopicimpulses originating in sleeve muscles around the orifices of pulmonary veins (PVs) were deemed tobe one of the most important reasons that trigger or drive atrial arrhythmia, which was calledmyocardial sleeve related arrhythmia. Electrical isolation by radiofrequency ablation is becominghighlight and proved to be an effective method for the arrhythmia. We report a 55-year-old man withparoxysmal atrial tachy-arrhythmias admitted for PV electrical isolation. An abscess was discoveredin right inferior lung before the operation. The arrhythmia was disappeared after resection of theabscess. It implies that for such sufferer and recidivist after ablation, the factors outside thepulmonary veins should be excluded or treated as far as possible, especially before radiofrequencyablation therapy. 展开更多
关键词 atrial arrhythmia pulmonary vein lung abscess
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Development of Aseptic Renal Abscess in a Patient with Non-Small-Cell Lung Cancer with ALK Translocation during Crizotinib Treatment
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作者 Luciana Franco do Prado de Carvalho Andrea Kazumi Shimada +4 位作者 Manuel Santos da Cruz Neto Lucila Soares da Silva Rocha Publio Cesar Cavalcante Viana Esper George Kallas Artur Katz 《Advances in Lung Cancer》 2015年第4期53-57,共5页
Background: Crizotinib is a tyrosine kinase inhibitor of ALK, MET and ROS1. In a safety database trial, it was suggested an association of Crizotinib with the development of renal cyst in patients with non-small-cell ... Background: Crizotinib is a tyrosine kinase inhibitor of ALK, MET and ROS1. In a safety database trial, it was suggested an association of Crizotinib with the development of renal cyst in patients with non-small-cell lung cancer (NSCLC). Aim: To report an uncommon side effect of Crizotinib in a patient with NSLC. Case Presentation: We report the case of a 68-year-old woman with NSCLC who developed bilateral progressive aseptic renal abscesses during Crizotinib treatment. Conclusion: Further studies may be necessary to determinate the risk of renal cyst development and the management of these complications. 展开更多
关键词 Non-Small-Cell lung Cancer CRIZOTINIB RENAL abscessES
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Prostatic abscess of Klebsiella pneumoniae complicating septic pulmonary emboli and meningitis: A case report and brief review 被引量:5
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作者 Jai-Wen Liu Tzu-Chieh Lin +2 位作者 Yao-Tien Chang Che-An Tsai Sung-Yuan Hu 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2017年第1期98-100,共3页
Prostatic abscess is a rare entity with an incidence of 0.5% to 2.5% in all prostate diseases and usually occurs in the 5th and 6th decades of life with immunocompromised status,Prostatic abscess might be a process of... Prostatic abscess is a rare entity with an incidence of 0.5% to 2.5% in all prostate diseases and usually occurs in the 5th and 6th decades of life with immunocompromised status,Prostatic abscess might be a process of evolution from acute prostatitis,Klebsiella pneumoniae is the leading microorganism in the diabetic patients of prostatic abscess in Taiwan,A 60-year-old diabetic man,with a one-week history of acute bacterial prostatitis was reported in this study,presenting to the emergency department with sudden altered mental status,The abdominal computed tomographic scan demonstrated lobulated prostatic abscess and multiple septic pulmonary emboli with lung abscesses,Analysis of cerebrospinal fluid showed white blood cells of 10 771 counts/mm3 with segmented neutrophils of 99%,Cultures of blood,cerebrospinal fluid and sputum yielded Klebsiella pneumoniae,We concluded that computed tomographic scan can make a definite diagnosis of prostatic abscess associated with complications and management with empiric antibiotics and adequate drainage is suggested. 展开更多
关键词 Klebsiella pneumoniae lung abscess MENINGITIS Prostatic abscess Septic emboli
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靶向二代测序在儿童肺脓肿病原诊断与治疗中的应用价值
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作者 张梦婷 毛国顺 +2 位作者 方辉 李桂涛 李利 《临床医学研究与实践》 2026年第8期65-69,共5页
目的探讨靶向二代测序(tNGS)技术在儿童肺脓肿病原诊断与治疗中的应用价值。方法回顾性分析2024年1月至2025年6月于阜阳市人民医院儿科住院的6例肺脓肿患儿的临床资料,记录根据tNGS检测结果指导的治疗调整及转归。结果6例患儿中,男5例,... 目的探讨靶向二代测序(tNGS)技术在儿童肺脓肿病原诊断与治疗中的应用价值。方法回顾性分析2024年1月至2025年6月于阜阳市人民医院儿科住院的6例肺脓肿患儿的临床资料,记录根据tNGS检测结果指导的治疗调整及转归。结果6例患儿中,男5例,女1例;年龄5岁3个月至14岁,中位年龄为11岁11个月。3例既往体质良好,3例肥胖。除1例患儿无发热外,5例患儿均有发热、咳嗽,其中咯血3例,胸痛2例,气促1例。合并胸腔积液4例,胸膜炎2例。4例白细胞计数(WBC)升高,6例中性粒细胞百分比(NEU%)升高,5例C反应蛋白(CRP)升高,3例降钙素原(PCT)升高;4例谷丙转氨酶(ALT)升高,3例谷草转氨酶(AST)升高,3例白蛋白(ALB)轻中度降低;6例D二聚体(D-D)升高,1例凝血酶原时间(PT)轻度延长。6例患儿影像学特征均表现为脓腔空洞伴有气液平。病变位于右肺中下叶1例、右肺下叶2例、左肺下叶3例。6例患儿的病原学检测中,tNGS的检出率达100.00%(6/6),显著高于传统培养的40.00%(2/5)。6例患儿均临床治愈出院,住院时间14~26 d(中位时间21.5 d),出院后口服抗菌药物序贯治疗。随访5周至5个月(中位时间11周),均预后良好,复查影像学显示脓肿较前明显吸收。结论tNGS是一种儿童肺脓肿病原诊断的重要辅助手段,可为精准治疗提供依据,有助于改善患儿预后。 展开更多
关键词 肺脓肿 靶向基因组测序 儿童 病原
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基于历代本草古籍挖掘肺痈用药特点
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作者 张欣怡 张洪春 《云南中医药大学学报》 2026年第1期82-87,共6页
目的挖掘本草著作中治疗肺痈的药物,指导临床用药。方法检索《中华医典》本草类中全部本草著作,根据纳入排除标准纳入药物,依据《中华人民共和国药典(2020年版)》进行四气五味及归经分析,根据药物的主治功效将其分类,结合本草著作中的... 目的挖掘本草著作中治疗肺痈的药物,指导临床用药。方法检索《中华医典》本草类中全部本草著作,根据纳入排除标准纳入药物,依据《中华人民共和国药典(2020年版)》进行四气五味及归经分析,根据药物的主治功效将其分类,结合本草著作中的有关论述,分析其治疗肺痈的特点。结果纳入药物24味,涉及本草著作45部,药性以寒性、微寒、平性为主,药味以甘味、苦味为主,归经以肺经为主,依据功效可分为化痰药、清热药、活血药、补虚药和排脓解毒药。结论肺痈治疗药物主要分为化痰药、清热药、活血药、补虚药和排脓解毒药5类,与肺痈痰、热、瘀、虚的发病基础相符,在临床治疗时可根据病情需要与药物特点进行选用。 展开更多
关键词 肺痈 中药 本草古籍
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Pulmonary abscess caused by Streptococcus pseudopneumoniae in a child:A case report and review of literature
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作者 Ran Ma Yan-Mei Wang +3 位作者 Hua Guan Li Zhang Wei Zhang Ling-Cai Chen 《World Journal of Radiology》 2024年第8期362-370,共9页
BACKGROUND Lung abscess found on chest X-ray and computed tomography examinations is rare in infants and young children.Several pathogens can cause lung abscesses,with the most common pathogens being anaerobes,Strepto... BACKGROUND Lung abscess found on chest X-ray and computed tomography examinations is rare in infants and young children.Several pathogens can cause lung abscesses,with the most common pathogens being anaerobes,Streptococci and Staphylococcus aureus.Streptococcus pseudopneumoniae(S.pseudopneumoniae)is a member of the Streptococcaceae family,and is mainly isolated from respiratory tract specimens.There are currently no cases of lung abscess caused by S.pseudopneumoniae in the literature.CASE SUMMARY A 2-year-old boy was admitted to hospital due to persistent cough and fever.Lung computed tomography examination suggested the formation of a lung abscess.His diagnosis was not confirmed by testing for serum respiratory pathogens(6 items),respiratory pathogen nucleic acid(27 items),and laboratory culture.Finally,metagenomic next-generation sequencing of bronchoalveolar lavage fluid revealed the presence of S.pseudopneumoniae,confirming its role in causing the lung abscess.After receiving antibiotic treatment,reexamination with lung computed tomography showed that the abscess was resorbed and the patient’s outcome was good.CONCLUSION This is the first report of a lung abscess in a child caused by S.pseudopneumoniae infection.Metagenomic next-generation sequencing of bronchoalveolar lavage fluid is helpful in achieving rapid and accurate pathogen identification. 展开更多
关键词 Streptococcus pseudopneumoniae lung abscess Children Bronchoalveolar lavage fluid Metagenomic nextgeneration sequencing Case report
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中心型肺癌的临床特征及误诊原因分析
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作者 刘洋 《临床误诊误治》 2026年第5期18-22,60,共6页
目的分析中心型肺癌误诊患者的临床特征、误诊原因,并总结防范误诊对策。方法回顾性分析2022年1月至2023年12月首诊误诊的9例中心型肺癌患者临床资料。结果2例以咳嗽、发热、白色泡沫痰、呼吸困难就诊,X线示肺叶渗出性病变、肺门模糊,C... 目的分析中心型肺癌误诊患者的临床特征、误诊原因,并总结防范误诊对策。方法回顾性分析2022年1月至2023年12月首诊误诊的9例中心型肺癌患者临床资料。结果2例以咳嗽、发热、白色泡沫痰、呼吸困难就诊,X线示肺叶渗出性病变、肺门模糊,CT示肺门周边高密度圆形影伴肺气肿或不张,误诊为浸润性肺结核。4例以咳嗽等呼吸道症状就诊,X线示肺门模糊,纹理紊乱,CT示肺门周边圆形肿块影,误诊为肺结核。2例以胸闷、气促、颈部肿胀就诊,X线示纵隔增宽,CT示纵隔类圆形肿块伴肺不张,误诊为纵隔肿瘤。1例以长期发热、咳脓血痰、胸痛就诊,CT示肺部实性病灶内有空洞形成,边缘模糊或有毛刺,误诊为肺脓肿。6例经支气管镜活检确诊,3例经痰检癌细胞阳性结合影像学确诊,均确诊为中心型肺癌,误诊时间1~5个月。3例因心肺功能差或晚期广泛转移行保守治疗(1例稳定)或放弃治疗(2例死亡),3例化疗后肿瘤稳定或缩小,1例放化疗后无复发,2例确诊后5 d内分别死于感染性休克及大咯血窒息。结论中心型肺癌早期症状不典型,易误诊。掌握其临床及影像学特点,对高危人群提高警惕,适时采用支气管镜活检、痰液细胞学检查等手段,并仔细鉴别,有助于减少误诊。 展开更多
关键词 中心型肺癌 误诊 肺结核 纵隔肿瘤 肺脓肿 临床特征
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Role of Partial Thoracoplasty in Lung Lesions —A Single Institute Experience
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作者 Binay Krishna Sarkar Krishnendu Chakraborty Pares Bandyopadhayay 《World Journal of Cardiovascular Surgery》 2019年第11期155-162,共8页
Thoracoplasty has been a useful procedure to control and cure recalcitrant lung lesions often as a last measure to treat pulmonary infections like post-?tubercular chronic empyema with fibrocavitary lesions and residu... Thoracoplasty has been a useful procedure to control and cure recalcitrant lung lesions often as a last measure to treat pulmonary infections like post-?tubercular chronic empyema with fibrocavitary lesions and residual pleural space infections after pulmonary resections. Long-standing empyemas with persistent discharge on drainage often respond poorly after decortication and?debridement alone due to non-expanding underlying lung tissue due to fibrotic changes. These cases often develop recurrent empyemas with sepsis with high morbidity and mortality. Similarly chronic space-occupying lung lesions with adjacent pulmonary damage and fibrosis leave a considerable residual space after surgery of these lesions and these persistent residual space leads to pleural space infections and empyema. In the presence of a large apical abscess and destruction of the apical pulmonary tissue forming a potential space confined by the bony thoracic cage and limited inferiorly by the rigid lining of the abscess, the cure and management of the chronic empyema especially the post-tubercular ones are particularly difficult. We address these cases in our series by performing partial thoracoplasty tailored to the site of the lesions in addition to other procedures. Partial thoracoplasty was found beneficial for selective cases of chronic empyema, obliteration of residual cavity after resectional surgery and management of the apical abscess. 展开更多
关键词 PARTIAL Thoracoplasty Chronic EMPYEMA Residual PLEURAL Space Infection APICAL lung abscess
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王玉光教授以阴阳、虚实、脏腑为纲辨证治疗支气管扩张症的经验 被引量:3
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作者 郭丽娅 房克英 王玉光 《世界中西医结合杂志》 2025年第3期503-507,共5页
支气管扩张症归属于中医学“肺痈”范畴,痰热壅肺是其重要病机。疾病初期以“痰”“火”等实邪为主要表现。随着病久耗伤,寒凉药物的反复应用或素体本虚,后期逐渐出现肺脾肾三脏阴阳气血的虚损。支气管扩张症患者病程较长,临床表现复杂... 支气管扩张症归属于中医学“肺痈”范畴,痰热壅肺是其重要病机。疾病初期以“痰”“火”等实邪为主要表现。随着病久耗伤,寒凉药物的反复应用或素体本虚,后期逐渐出现肺脾肾三脏阴阳气血的虚损。支气管扩张症患者病程较长,临床表现复杂,常辨证为虚实夹杂,寒热错杂。临床施治中,通过祛邪与脏腑功能的调补,从而达到缓解症状,减少疾病迁延不愈的目的。文章围绕支气管扩张症的中医病机、治则治法以及主要临证方药并结合临床验案,系统介绍王玉光教授治疗支气管扩张症的临证经验。 展开更多
关键词 支气管扩张症 肺痈 中医药 名医经验
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初诊老年LADA合并高毒力肺炎克雷伯菌致多器官感染1例报告及文献复习
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作者 李霞 林梅 《江汉大学学报(自然科学版)》 2025年第6期62-67,共6页
目的报告1例以乏力就诊,应用二代测序技术(NGS)确诊老年成人隐匿性自身免疫糖尿病(LADA)并发高毒力肺炎克雷伯菌(hvKP)致多器官感染患者的临床诊疗及转归,力求增加医务人员对hvKP及LADA的认识和了解,为临床提供该类患者的诊疗思路。方... 目的报告1例以乏力就诊,应用二代测序技术(NGS)确诊老年成人隐匿性自身免疫糖尿病(LADA)并发高毒力肺炎克雷伯菌(hvKP)致多器官感染患者的临床诊疗及转归,力求增加医务人员对hvKP及LADA的认识和了解,为临床提供该类患者的诊疗思路。方法回顾性分析1例初诊老年LADA并发高毒力肺炎克雷伯菌致多器官感染患者的病例资料、诊断过程、治疗方案及转归,并复习相关文献进行探讨。结果经积极的强效抗感染、肝脓肿穿刺引流、控制血糖、营养支持等综合治疗,患者转归良好。结论hvKP侵袭性强,糖尿病患者是hvKP主要易感人群,快速明确诊断并加强引流联合强效的抗感染、营养支持、严格血糖控制等综合措施有助于改善患者预后,新型NGS病原体检测技术在高风险人群出现多器官严重感染时可帮助临床医师快速诊断病原菌。 展开更多
关键词 成人隐匿性自身免疫糖尿病 糖尿病酮症酸中毒 高毒力肺炎克雷伯菌 肺脓肿 肝脓肿
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假肺炎链球菌所致儿童罹患肺脓肿:个案报道并文献复习
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作者 马冉 袁博 +3 位作者 管华 张丽 章伟 陈彩玲 《罕少疾病杂志》 2025年第5期6-9,共4页
目的肺脓肿在婴幼儿中并不常见,多种病原可导致肺脓肿,国内外文献中很少报道假肺炎链球菌所致肺脓肿病例,本文探讨假肺炎链球菌感染导致的儿童肺脓肿的临床特点、诊断、治疗及疾病转归,提高临床医生对该菌株的了解。方法分析1例石河子... 目的肺脓肿在婴幼儿中并不常见,多种病原可导致肺脓肿,国内外文献中很少报道假肺炎链球菌所致肺脓肿病例,本文探讨假肺炎链球菌感染导致的儿童肺脓肿的临床特点、诊断、治疗及疾病转归,提高临床医生对该菌株的了解。方法分析1例石河子大学第一附属医院儿科2023年9月收治的一名假肺炎链球菌所致罹患肺脓肿患儿的临床特点。结果这名2岁男童以“咳嗽7天伴发热5天”入院,病程中虽然无呼吸困难、胸痛表现,体格检查听诊双肺呼吸音对称,两肺未闻及啰音,但完善肺CT提示肺脓肿形成;完善血清抗体呼吸道六联检、呼吸道病原体核酸27项、实验室培养等均未发现病原体,最终完善支气管镜送检肺泡灌洗液(BALF)行宏基因二代测序(mNGS)检测到了假肺炎链球菌,结合患儿的症状、体征,最终诊断假肺炎链球菌导致肺脓肿。结论患儿接受了抗生素及肺泡灌洗治疗后,复查肺CT提示脓肿灶吸收,预后良好,定期随访中。 展开更多
关键词 假肺炎链球菌 肺脓肿 儿童 肺泡灌洗液 宏基因测序
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结合分子对接探讨鱼腥草注射液治疗肺脓肿的网络药理学研究
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作者 王雯舟 黄栋 《中医药临床杂志》 2025年第11期2233-2238,共6页
目的:该研究旨在通过网络药理学方法结合分子对接技术,探讨鱼腥草注射液治疗肺脓肿的潜在作用机制。方法:通过检索TCMSP数据库获取鱼腥草中有效成分,在HERB数据库获取各有效成分的作用靶点信息,并与GeneCards数据库获得的肺脓肿的疾病... 目的:该研究旨在通过网络药理学方法结合分子对接技术,探讨鱼腥草注射液治疗肺脓肿的潜在作用机制。方法:通过检索TCMSP数据库获取鱼腥草中有效成分,在HERB数据库获取各有效成分的作用靶点信息,并与GeneCards数据库获得的肺脓肿的疾病靶点取交集处理,在STRING数据库中进行交集靶点对应蛋白的相互作用分析,经CytoScape分析后获取核心靶点,在DAVID数据库进行GO功能富集分析和KEGG通路富集分析,并对关键靶点与活性成分进行分子对接验证。结果:鱼腥草注射液通过调控PI3K-AKT信号通路、MAPK 信号通路、IL-17信号通路等通路,作用于AKT1、EGFR、PPARG等多个靶点,发挥治疗肺脓肿的作用,分子对接结果表明活性成分与关键靶点具有良好的结合活性。结论:该研究为鱼腥草注射液治疗肺脓肿的机制研究提供了新的视角和理论依据。 展开更多
关键词 鱼腥草注射液 肺脓肿 网络药理学 分子对接
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从“热郁肺络,气虚痰瘀”分期论治小儿坏死性肺炎
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作者 胡姣姣 史艳平 +1 位作者 张子薇 李隽 《中国中医急症》 2025年第4期633-637,共5页
小儿坏死性肺炎是儿童社区获得性肺炎严重并发症,为中医学“肺炎喘嗽”之重症,属于“肺痈”范畴。邪热郁积于肺络是该病的关键病机;小儿肺脾不足,邪热耗气伤津,津停为痰、血滞为瘀,疾病的发展离不开热、虚、痰、瘀。从“热郁肺络,气虚... 小儿坏死性肺炎是儿童社区获得性肺炎严重并发症,为中医学“肺炎喘嗽”之重症,属于“肺痈”范畴。邪热郁积于肺络是该病的关键病机;小儿肺脾不足,邪热耗气伤津,津停为痰、血滞为瘀,疾病的发展离不开热、虚、痰、瘀。从“热郁肺络,气虚痰瘀”探讨小儿坏死性肺炎的辨治思路,认为邪热未清、气阴两伤、痰瘀阻络是核心病机,提出以宣肺清热、养阴益气、化痰蠲络、活血祛瘀为主要治法,运用清热活血方、清肺疏络饮、六君四物汤分期论治小儿坏死性肺炎,为临床治疗提供思路。附案例1则,以资验证。 展开更多
关键词 坏死性肺炎 肺痈 小儿 热郁肺络 气虚痰瘀
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基于《医学衷中参西录》探析张锡纯肺痈诊治特色
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作者 胡滢瑄 冯淬灵 《吉林中医药》 2025年第11期1249-1252,共4页
张锡纯著《医学衷中参西录》认为外感、内伤均可导致肺痈发病,提出肺痈以热毒蕴肺、肺中腐烂为核心病机,治疗当分期论治。《医学衷中参西录》之“治肺病方”论述肺痈的辨治思路,并创立3首方剂对肺痈分期论治:成痈期以清金解毒汤清热解毒... 张锡纯著《医学衷中参西录》认为外感、内伤均可导致肺痈发病,提出肺痈以热毒蕴肺、肺中腐烂为核心病机,治疗当分期论治。《医学衷中参西录》之“治肺病方”论述肺痈的辨治思路,并创立3首方剂对肺痈分期论治:成痈期以清金解毒汤清热解毒,溃脓期以清凉华盖饮活血化瘀,恢复期以清金益气汤益气滋阴。张锡纯对甘草、犀黄丸、阿司匹林在肺痈治疗中的应用有独到见解。总结张锡纯《医学衷中参西录》肺痈的诊治特色,以期为临床肺痈治疗提供参考。 展开更多
关键词 肺痈 张锡纯 《医学衷中参西录》
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据出土医简校读汉唐医书四则
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作者 包伯航 蔡业峰 冯惠童 《中医药导报》 2025年第8期228-230,236,共4页
根据新近出土的天回汉简《六十病方》、胡家草场汉简《医方》,对汉唐传世医书中四则存在理解障碍或争议的文句进行了校勘,提出了新的意见,认为:《金匮要略方》葶苈大枣泻肺汤的主治病证“肺痈”应读作“肺壅”;《外台秘要方》尿精丸的... 根据新近出土的天回汉简《六十病方》、胡家草场汉简《医方》,对汉唐传世医书中四则存在理解障碍或争议的文句进行了校勘,提出了新的意见,认为:《金匮要略方》葶苈大枣泻肺汤的主治病证“肺痈”应读作“肺壅”;《外台秘要方》尿精丸的赋形剂“牛膝”应为“美漆”或“生漆”之形误;唐代医书中的病名“脾疸”“肺疸”分别系由汉代医简中的“小肠疸”“膏瘅”更名而来,《诸病源候论》中的“体疸”当为“髓疸”之误;《千金翼方》桑根汤的主治证候“日饮一石水”应为“日饮一石成水”之脱文。 展开更多
关键词 出土医简 《金匮要略方》 《外台秘要方》 《千金翼方》 肺痈 牛膝 文献考证
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左氧联合美平联合氟康唑在肺炎合并肺脓肿中的治疗效果探讨
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作者 解建慧 《智慧健康》 2025年第18期87-90,共4页
目的探讨左氧联合美平联合氟康唑在肺炎合并肺脓肿中的治疗效果。方法将2019年1月—2024年10月在本院治疗的40例肺炎合并肺脓肿患者随机分为两组,每组20例。对照组使用左氧氟沙星联合美罗培南(美平)治疗,观察组在此基础上使用氟康唑治疗... 目的探讨左氧联合美平联合氟康唑在肺炎合并肺脓肿中的治疗效果。方法将2019年1月—2024年10月在本院治疗的40例肺炎合并肺脓肿患者随机分为两组,每组20例。对照组使用左氧氟沙星联合美罗培南(美平)治疗,观察组在此基础上使用氟康唑治疗,对比两组的临床疗效、症状改善指标、炎症因子。结果观察组治疗有效率为95.00%,明显高于对照组的65.00%(P<0.05);观察组体温恢复正常时间、咳嗽缓解时间、呼吸困难缓解时间、血常规恢复正常时间、住院时间均短于对照组(P<0.05);观察组治疗5 d的WBC、CRP、PCT水平均低于对照组(P<0.05)。结论左氧联合美平联合氟康唑在肺炎合并肺脓肿中的治疗效果显著,能加快病情缓解速度,提升抗感染作用。 展开更多
关键词 肺炎合并肺脓肿 左氧氟沙星 美罗培南 氟康唑 治疗效果
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