摘要
目的肺脓肿在婴幼儿中并不常见,多种病原可导致肺脓肿,国内外文献中很少报道假肺炎链球菌所致肺脓肿病例,本文探讨假肺炎链球菌感染导致的儿童肺脓肿的临床特点、诊断、治疗及疾病转归,提高临床医生对该菌株的了解。方法分析1例石河子大学第一附属医院儿科2023年9月收治的一名假肺炎链球菌所致罹患肺脓肿患儿的临床特点。结果这名2岁男童以“咳嗽7天伴发热5天”入院,病程中虽然无呼吸困难、胸痛表现,体格检查听诊双肺呼吸音对称,两肺未闻及啰音,但完善肺CT提示肺脓肿形成;完善血清抗体呼吸道六联检、呼吸道病原体核酸27项、实验室培养等均未发现病原体,最终完善支气管镜送检肺泡灌洗液(BALF)行宏基因二代测序(mNGS)检测到了假肺炎链球菌,结合患儿的症状、体征,最终诊断假肺炎链球菌导致肺脓肿。结论患儿接受了抗生素及肺泡灌洗治疗后,复查肺CT提示脓肿灶吸收,预后良好,定期随访中。
Objective Lung abscess is rare in infants and young children.Several pathogens can cause lung abscesses,with the most common pathogens being anaerobes and streptococci.Cases of lung abscess caused by Streptococcus pseudopneumoniae are rarely reported in the literature,both domestically and internationally.To explore the clinical treatment,diagnosis,treatment and prognosis of Pulmonary Abscess in children caused by Streptococcus pseudopneumoniae infection,so as to improve clinicians'conception of the disease.Methods Analysis of the clinical characteristics of a child with lung abscess caused by Streptococcus pseudopneumoniae admitted to The First Affiliated Hospital of Shihezi University in September 2023.Results In this case report,a 2-year-old boy was admitted with a history of"cough for 7 days and fever for 5 days".Although there were no signs of dyspnea and chest pain,the presence of symmetrical respiratory sounds in both lungs,the absence of drywet rales in both lungs,and a thorough lung CT examination suggested the formation of a lung abscess.No pathogen was found by the erum respiratory pathogens(6 items),respiratory pathogen nucleic acid test(27 items),and laboratory culture.Finally,metagenomic next-generation sequencing using bronchoalveolar lavage fluid samples revealed the presence of S.pseudopneumoniae,confirming its role in causing the lung abscess.Conclusion After receiving antibiotics and bronchoalveolar lavage treatment,a reexamination of the lung CT showed that the abscess was absorbed and the prognosis was good.
作者
马冉
袁博
管华
张丽
章伟
陈彩玲
MA Ran;YUAN Bo;GUAN Hua;ZHANG Li;ZHANG Wei;CHEN Cai-ling(School of Medicine,Shihezi University,Shihezi 832000,Xinjiang,China;Department of Pediatrics,The First Affiliated Hospital of Shihezi University,Shihezi 832000,Xinjiang,China;Department of Pediatrics,Corps Fourth Division Hospital,Yining 839300,Xinjiang,China;Department of Pediatrics,Corps First Division Hospital,Aksu 843000,Xinjiang,China)
出处
《罕少疾病杂志》
2025年第5期6-9,共4页
Journal of Rare and Uncommon Diseases
基金
兵团指导性科技计划(2022ZD031)
八师石河子市财政科技计划项目(2022NY01)
石河子大学科研项目(ZZZC202072A)。
关键词
假肺炎链球菌
肺脓肿
儿童
肺泡灌洗液
宏基因测序
Streptococcus Pseudopneumoniae
Lung Abscess
Children
Bronchoalveolar Lavage Fluid
Metagenomic Next-generation Sequencing
