This study aimed to determine age-related fall risk characteristics among 2324 Japanese community-dwelling elderly through comparisons between young-old and old-old populations. Fall risk characteristics associated wi...This study aimed to determine age-related fall risk characteristics among 2324 Japanese community-dwelling elderly through comparisons between young-old and old-old populations. Fall risk characteristics associated with “physical function”, “disease and physical symptom”, “behavior and character”, and “environment” were evaluated, and whether each individual has a high-risk symptom for each risk factor was assessed. The frequencies of individuals for all 16 risk types, which were determined by a combination of the four risk factors, were calculated. The prevalence of each risk type and the incidence of falling in each risk type were calculated within the young-old and old-old groups, and significant differences between these percentages were examined using the chi-square test. The prevalence of the no high-risk symptom group was significantly lower in the old-old group (17.0%) than in the young-old group (45.2%). Although there was no significant difference in the prevalence of the single high-risk symptom group, the prevalence of the two or more high-risk symptom groups was significantly higher in the old-old group. The incidence of fall among the elderly with high-risk symptoms did not change with age, although the incidence of fall with no high-risk symptom increased in the old-old group. Furthermore, high prevalence was observed in risk types with high-risk symptoms for “physical function” and “behavior and character”, particularly in the symptoms of gait, going up and down stairs, and fear of falling. These age-related differences are interesting and meaningful.展开更多
目的分析南京地区人群高危型人乳头状瘤病毒(high-risk human papillomavirus,HR-HPV)感染情况以及检测结果基因分型的分布。方法收集2019年1月至2023年5月就诊于南京医科大学第一附属医院行HPV检测的3048例患者作为研究对象,其中包括2...目的分析南京地区人群高危型人乳头状瘤病毒(high-risk human papillomavirus,HR-HPV)感染情况以及检测结果基因分型的分布。方法收集2019年1月至2023年5月就诊于南京医科大学第一附属医院行HPV检测的3048例患者作为研究对象,其中包括2781名女性和267名男性。采用实时荧光PCR技术检测HR-HPV的基因型,分析HPV感染率、感染亚型及不同年龄、性别患者的基因型分布特点。结果3048例患者中,共有598例HPV阳性感染者,总阳性率为19.62%。HPV感染率前5位由高到低依次是52型(191,6.27%)、58型(114,3.74%)、16型(90,2.95%)、51型(54,1.77%)和68型(51,1.67%)。阳性患者中,男性51(8.53%)例,女性547(91.47%)例。其中,女性阳性占比较高的3种亚型为:52型(175,29.26%)、58型(107,17.89%)和16型(82,13.71%);男性阳性占比较高的3种亚型为52型(16,2.68%)、18型(9,1.51%)和16型(8,1.34%)。患者年龄分布在4~81岁之间,中位年龄为38岁。根据患者年龄分成6个年龄组(≤20岁、21~30岁、31~40岁、41~50岁、51~60岁和>60岁),各年龄组间感染阳性率差异有统计学意义(χ^(2)=30.425,P<0.05),31~40岁组最高达36.46%(218/598)。分析不同年龄段阳性检出率,≤20岁年龄段人群的检出率最高,为40.63%(13/32)。HPV感染者中,单一型别感染例数占比较高为74.58%(446/598)。结论南京地区HR-HPV感染亚型以52型、58型、16型最常见,其次为51型和68型。研究HR-HPV基因型分布特点为南京地区人群HR-HPV感染及防治提供依据,推荐适龄男性及女性接种HPV疫苗、加强高危人群的HPV筛查。展开更多
文摘This study aimed to determine age-related fall risk characteristics among 2324 Japanese community-dwelling elderly through comparisons between young-old and old-old populations. Fall risk characteristics associated with “physical function”, “disease and physical symptom”, “behavior and character”, and “environment” were evaluated, and whether each individual has a high-risk symptom for each risk factor was assessed. The frequencies of individuals for all 16 risk types, which were determined by a combination of the four risk factors, were calculated. The prevalence of each risk type and the incidence of falling in each risk type were calculated within the young-old and old-old groups, and significant differences between these percentages were examined using the chi-square test. The prevalence of the no high-risk symptom group was significantly lower in the old-old group (17.0%) than in the young-old group (45.2%). Although there was no significant difference in the prevalence of the single high-risk symptom group, the prevalence of the two or more high-risk symptom groups was significantly higher in the old-old group. The incidence of fall among the elderly with high-risk symptoms did not change with age, although the incidence of fall with no high-risk symptom increased in the old-old group. Furthermore, high prevalence was observed in risk types with high-risk symptoms for “physical function” and “behavior and character”, particularly in the symptoms of gait, going up and down stairs, and fear of falling. These age-related differences are interesting and meaningful.
文摘目的分析南京地区人群高危型人乳头状瘤病毒(high-risk human papillomavirus,HR-HPV)感染情况以及检测结果基因分型的分布。方法收集2019年1月至2023年5月就诊于南京医科大学第一附属医院行HPV检测的3048例患者作为研究对象,其中包括2781名女性和267名男性。采用实时荧光PCR技术检测HR-HPV的基因型,分析HPV感染率、感染亚型及不同年龄、性别患者的基因型分布特点。结果3048例患者中,共有598例HPV阳性感染者,总阳性率为19.62%。HPV感染率前5位由高到低依次是52型(191,6.27%)、58型(114,3.74%)、16型(90,2.95%)、51型(54,1.77%)和68型(51,1.67%)。阳性患者中,男性51(8.53%)例,女性547(91.47%)例。其中,女性阳性占比较高的3种亚型为:52型(175,29.26%)、58型(107,17.89%)和16型(82,13.71%);男性阳性占比较高的3种亚型为52型(16,2.68%)、18型(9,1.51%)和16型(8,1.34%)。患者年龄分布在4~81岁之间,中位年龄为38岁。根据患者年龄分成6个年龄组(≤20岁、21~30岁、31~40岁、41~50岁、51~60岁和>60岁),各年龄组间感染阳性率差异有统计学意义(χ^(2)=30.425,P<0.05),31~40岁组最高达36.46%(218/598)。分析不同年龄段阳性检出率,≤20岁年龄段人群的检出率最高,为40.63%(13/32)。HPV感染者中,单一型别感染例数占比较高为74.58%(446/598)。结论南京地区HR-HPV感染亚型以52型、58型、16型最常见,其次为51型和68型。研究HR-HPV基因型分布特点为南京地区人群HR-HPV感染及防治提供依据,推荐适龄男性及女性接种HPV疫苗、加强高危人群的HPV筛查。
