Objective:To observe the effects of Methyl Carboprost and Diclofenac Sodium on opening orifice of uterus and pain controlling in patients with uterine cervix cancer (UCC) when receiving intracavitary brachytherapy. Me...Objective:To observe the effects of Methyl Carboprost and Diclofenac Sodium on opening orifice of uterus and pain controlling in patients with uterine cervix cancer (UCC) when receiving intracavitary brachytherapy. Methods: Sixty patients with UCC of stage IIA-IIIB were divided into three groups randomly before receiving the intracavitary brachytherapy: the patients in group A received Methyl Carboprost in the hind fornix of the vagina, group B received Diclofenac Sodium in the anus, while group C was the control group. Results: The painlessness rates in groups A, B and C were 89.9%, 91.3% and 36.4%, respectively. The incidences of patients with relaxed uterus cervix in groups A, B and C were 91.7%, 85.9% and 48.9%, respectively. Conclusion: Methyl Carboprost and Diclofenac Sodium are useful in relaxing uterus cervix and pain controlling in patients with UCC when receiving intracavitary brachytherapy.展开更多
The objective of this study was to investigate the clinical efficacy of carboprost tromethamine combined with mifepristone in the treatment of uterine fibroids.A total of 66 patients with uterine fibroids admitted to ...The objective of this study was to investigate the clinical efficacy of carboprost tromethamine combined with mifepristone in the treatment of uterine fibroids.A total of 66 patients with uterine fibroids admitted to our hospital between April 2018 and January 2019 were selected as subjects.According to the two different treatment methods,patients were divided equally:The observation group and the control group,each group of 33 people.The oxytocin drug treatment was medicated to the control group,and the prostaglandin tromethamine combined with mifepristone was medicated to the observation group.The treatment effect,adverse reaction,operation,and uterine muscle before and after surgery were observed in these two groups:Tumor tissue progesterone receptor and estrogen receptor levels.The clinical treatment effect of the observation group was 93.94%,and the clinical treatment effect of the control group was 60.61%.The clinical treatment effect of the observation group was significantly higher than that of the control group;furthermore,the incidence of adverse reactions in the observation group in terms of rash,fatigue,nausea,and vomiting was much lower than the control group and could observe a significant difference.Finally,in observation group,the amount of intraoperative blood loss,operation time,and hospitalization time was better than those of the control group.The progesterone receptor and estrogen receptor levels in the uterine fibroid tissue after surgery should also be better than the control group,and it is worth to make a further comparison.Carboprost tromethamine combined with mifepristone is effective in the treatment of uterine fibroids and can be further developed.展开更多
Objective: to observe the effect of carboprost tromethamine injection on postpartum hemorrhage patients caused by placental abruption. Methods: the patients were randomly divided into two groups, the control group was...Objective: to observe the effect of carboprost tromethamine injection on postpartum hemorrhage patients caused by placental abruption. Methods: the patients were randomly divided into two groups, the control group was treated with routine hemostasis, and the observation group was treated with carboprost tromethamine injection. Results: the therapeutic effect and postpartum situation of the observation group were better than those of the control group (P < 0.05). Conclusion: based on the patients with postpartum hemorrhage caused by placental abruption, the treatment is completed with the help of carboprost tromethamine injection. The treatment effect is more obvious, which is beneficial to promote the improvement of postpartum conditions of patients.展开更多
目的:探讨葡萄糖酸钙联合卡前列素氨丁三醇对双胎剖宫产产后出血的预防效果。方法:回顾性分析2022年1月—2024年8月在抚州市第一人民医院行剖宫产的双胎产妇100例的临床资料,根据治疗方法不同分为对照组和观察组,各50例。对照组采取常...目的:探讨葡萄糖酸钙联合卡前列素氨丁三醇对双胎剖宫产产后出血的预防效果。方法:回顾性分析2022年1月—2024年8月在抚州市第一人民医院行剖宫产的双胎产妇100例的临床资料,根据治疗方法不同分为对照组和观察组,各50例。对照组采取常规产后出血预防处理措施,观察组在常规处理基础上增加葡萄糖酸钙联合卡前列素氨丁三醇。比较两组产后24 h出血量、血常规及凝血功能指标水平,并记录产后出血和手术止血情况。结果:观察组产后24 h出血量少于对照组,产后24 h RBC、红细胞压积、Hb高于对照组,PT、APTT短于对照组(P<0.05)。两组产后出血率、子宫切除率、子宫动脉栓塞率相比差异无统计学意义(P>0.05)。结论:葡萄糖酸钙联合卡前列素氨丁三醇在双胎剖宫产产妇中的应用效果较好,有助于减少产后24h出血量。展开更多
目的:以宫缩乏力性产后出血(PPH)患者为研究对象,探究马来酸麦角新碱和卡前列素氨丁三醇联合用药的疗效,以及对患者凝血功能的影响。方法:选择景德镇市第一人民医院妇产科2022年1月—2024年10月收治的宫缩乏力性PPH患者,共80例,按照随...目的:以宫缩乏力性产后出血(PPH)患者为研究对象,探究马来酸麦角新碱和卡前列素氨丁三醇联合用药的疗效,以及对患者凝血功能的影响。方法:选择景德镇市第一人民医院妇产科2022年1月—2024年10月收治的宫缩乏力性PPH患者,共80例,按照随机数字表法,将患者分为试验组和对照组,各40例。对照组采用卡前列素氨丁三醇治疗,试验组在对照组基础上联合马来酸麦角新碱治疗。比较两组血小板(PLT)、血红蛋白(Hb)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶原时间(PT)、D-二聚体(D-D),以及疗效及不良反应发生情况。结果:试验组总有效率高于对照组(P<0.05)。两组治疗前及治疗后1 d PLT、Hb水平比较,差异均无统计学意义(P>0.05)。两组治疗前凝血功能指标比较,差异均无统计学意义(P>0.05);治疗后1 d,两组TT、PT、APTT均显著缩短,试验组均较对照组短,FIB水平均显著升高,试验组较对照组高,D-D水平均降低,试验组较对照组低(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:对于宫缩乏力性PPH患者,马来酸麦角新碱和卡前列素氨丁三醇联合用药的疗效优,可显著改善患者凝血功能,且安全性良好。展开更多
文摘Objective:To observe the effects of Methyl Carboprost and Diclofenac Sodium on opening orifice of uterus and pain controlling in patients with uterine cervix cancer (UCC) when receiving intracavitary brachytherapy. Methods: Sixty patients with UCC of stage IIA-IIIB were divided into three groups randomly before receiving the intracavitary brachytherapy: the patients in group A received Methyl Carboprost in the hind fornix of the vagina, group B received Diclofenac Sodium in the anus, while group C was the control group. Results: The painlessness rates in groups A, B and C were 89.9%, 91.3% and 36.4%, respectively. The incidences of patients with relaxed uterus cervix in groups A, B and C were 91.7%, 85.9% and 48.9%, respectively. Conclusion: Methyl Carboprost and Diclofenac Sodium are useful in relaxing uterus cervix and pain controlling in patients with UCC when receiving intracavitary brachytherapy.
文摘The objective of this study was to investigate the clinical efficacy of carboprost tromethamine combined with mifepristone in the treatment of uterine fibroids.A total of 66 patients with uterine fibroids admitted to our hospital between April 2018 and January 2019 were selected as subjects.According to the two different treatment methods,patients were divided equally:The observation group and the control group,each group of 33 people.The oxytocin drug treatment was medicated to the control group,and the prostaglandin tromethamine combined with mifepristone was medicated to the observation group.The treatment effect,adverse reaction,operation,and uterine muscle before and after surgery were observed in these two groups:Tumor tissue progesterone receptor and estrogen receptor levels.The clinical treatment effect of the observation group was 93.94%,and the clinical treatment effect of the control group was 60.61%.The clinical treatment effect of the observation group was significantly higher than that of the control group;furthermore,the incidence of adverse reactions in the observation group in terms of rash,fatigue,nausea,and vomiting was much lower than the control group and could observe a significant difference.Finally,in observation group,the amount of intraoperative blood loss,operation time,and hospitalization time was better than those of the control group.The progesterone receptor and estrogen receptor levels in the uterine fibroid tissue after surgery should also be better than the control group,and it is worth to make a further comparison.Carboprost tromethamine combined with mifepristone is effective in the treatment of uterine fibroids and can be further developed.
文摘Objective: to observe the effect of carboprost tromethamine injection on postpartum hemorrhage patients caused by placental abruption. Methods: the patients were randomly divided into two groups, the control group was treated with routine hemostasis, and the observation group was treated with carboprost tromethamine injection. Results: the therapeutic effect and postpartum situation of the observation group were better than those of the control group (P < 0.05). Conclusion: based on the patients with postpartum hemorrhage caused by placental abruption, the treatment is completed with the help of carboprost tromethamine injection. The treatment effect is more obvious, which is beneficial to promote the improvement of postpartum conditions of patients.
文摘目的:探讨葡萄糖酸钙联合卡前列素氨丁三醇对双胎剖宫产产后出血的预防效果。方法:回顾性分析2022年1月—2024年8月在抚州市第一人民医院行剖宫产的双胎产妇100例的临床资料,根据治疗方法不同分为对照组和观察组,各50例。对照组采取常规产后出血预防处理措施,观察组在常规处理基础上增加葡萄糖酸钙联合卡前列素氨丁三醇。比较两组产后24 h出血量、血常规及凝血功能指标水平,并记录产后出血和手术止血情况。结果:观察组产后24 h出血量少于对照组,产后24 h RBC、红细胞压积、Hb高于对照组,PT、APTT短于对照组(P<0.05)。两组产后出血率、子宫切除率、子宫动脉栓塞率相比差异无统计学意义(P>0.05)。结论:葡萄糖酸钙联合卡前列素氨丁三醇在双胎剖宫产产妇中的应用效果较好,有助于减少产后24h出血量。
文摘目的:以宫缩乏力性产后出血(PPH)患者为研究对象,探究马来酸麦角新碱和卡前列素氨丁三醇联合用药的疗效,以及对患者凝血功能的影响。方法:选择景德镇市第一人民医院妇产科2022年1月—2024年10月收治的宫缩乏力性PPH患者,共80例,按照随机数字表法,将患者分为试验组和对照组,各40例。对照组采用卡前列素氨丁三醇治疗,试验组在对照组基础上联合马来酸麦角新碱治疗。比较两组血小板(PLT)、血红蛋白(Hb)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶原时间(PT)、D-二聚体(D-D),以及疗效及不良反应发生情况。结果:试验组总有效率高于对照组(P<0.05)。两组治疗前及治疗后1 d PLT、Hb水平比较,差异均无统计学意义(P>0.05)。两组治疗前凝血功能指标比较,差异均无统计学意义(P>0.05);治疗后1 d,两组TT、PT、APTT均显著缩短,试验组均较对照组短,FIB水平均显著升高,试验组较对照组高,D-D水平均降低,试验组较对照组低(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:对于宫缩乏力性PPH患者,马来酸麦角新碱和卡前列素氨丁三醇联合用药的疗效优,可显著改善患者凝血功能,且安全性良好。
