Hairdressers are exposed to numerous skin-damaging factors, such as wet work, skin irritants, and thermal changes. Skin protection is a very important factor for the prevention of occupational skin disorders. Therefor...Hairdressers are exposed to numerous skin-damaging factors, such as wet work, skin irritants, and thermal changes. Skin protection is a very important factor for the prevention of occupational skin disorders. Therefore, we evaluated a hand cream that was specially formulated for highly stressed skin with regard to its capability to reduce dry, rough, and scaly skin. The objective of this study was to conduct a controlled use test of a barrier repair cream containing pseudo-ceramide and demonstrate its efficacy for hairdressers with dry, sensitive hands and/or occupational skin disorders. A total of 30 hairdressers (29 females and 1 male, aged 20 - 67) participated in the study. All subjects suffered from dry hands. Subjects applied the test cream on their hands for 28 days (four weeks). For each subject, the skin surface topography of the hands was measured by the Surface Evaluation of Living Skin (SELS) system at day 14 (week 2) and day 28 (week 4). Dryness, scaling, cracking, redness, and itchiness were evaluated and graded by experts at week 2 and week 4, and then compared to baselines. All 30 subjects completed the study. A comparison of the changes from baseline to endpoint revealed a statistically significant reduction in skin roughness, scaling, and volume measured according to SELS. These data were confirmed by photographic documentation. The results were further supported by the expert evaluation. For the symptoms dryness and scaling, improvement could be observed in almost all regions of the hands. In addition, according to subjective assessments of overall hand skin condition and the hand cream, subjects reported clear improvement over time (p value below 0.001) and good efficacy of the product. In this study, the test hand cream showed excellent skin compatibility. Therefore, the hand cream may be effective for hairdressers with dry, sensitive hands and/or occupational skin disorders.展开更多
The epidermis, and in particular its outermost layer, the stratum corneum, contributes much of the barrier function of the skin and is a readily visible representation of skin health. Maintaining the health of the ski...The epidermis, and in particular its outermost layer, the stratum corneum, contributes much of the barrier function of the skin and is a readily visible representation of skin health. Maintaining the health of the skin barrier has arguably become more important than ever in the modern world, in which a large majority of people are exposed to environmental insults. These external factors can damage the integrity of the skin barrier and prematurely age the skin. Therefore, it has become increasingly important to maintain and protect the stratum corneum. Here, we briefly review the complex, multilayered structure of the skin and relate it to clinically translatable function, with an emphasis on the stratum corneum. In the context of epidermal structure and function, the formulation and clinical data for Phelityl® Reviving Cream will be reviewed. Phelityl Reviving Cream was shown to be associated with improvements in both immediate- and long-term parameters, including a significant positive effect on the skin barrier and immediate and long-lasting hydration.展开更多
目的:探讨薇诺娜屏障特护霜对光动力治疗痤疮后炎症皮损的修复作用。方法:选取2020年10月-2021年2月笔者医院收治的76例痤疮患者,采用随机数字表法分为对照组和观察组,每组38例。对照组采用光动力治疗后外用创福康敷料,观察组在对照组...目的:探讨薇诺娜屏障特护霜对光动力治疗痤疮后炎症皮损的修复作用。方法:选取2020年10月-2021年2月笔者医院收治的76例痤疮患者,采用随机数字表法分为对照组和观察组,每组38例。对照组采用光动力治疗后外用创福康敷料,观察组在对照组治疗基础上予以薇诺娜屏障特护霜涂抹,两组均治疗3周,比较两组治疗效果、炎症反应症状消退时间以及治疗前后面部皮肤屏障功能。结果:观察组治疗有效率89.47%,对照组为86.84%,两组比较差异无统计学意义(P>0.05);观察组红肿、灼热、疼痛、干燥脱屑等炎症反应症状消退时间均短于对照组,差异有统计学意义(P<0.05);与治疗前比较,两组治疗后经皮水分丢失量(Transepidermal water loss,TEWL)均下降,且观察组低于对照组,差异有统计学意义(P<0.05);角质层含水量(The water content of the stratum corneum,WCSC)值均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。结论:对于光动力治疗痤疮后炎性皮损,在常规应用创福康胶原敷料的基础上外用薇诺娜屏障特护霜治疗可促进患者炎症反应症状的消退,更有利于面部炎性皮损的修复及皮肤屏障功能的改善,疗效确切。展开更多
文摘Hairdressers are exposed to numerous skin-damaging factors, such as wet work, skin irritants, and thermal changes. Skin protection is a very important factor for the prevention of occupational skin disorders. Therefore, we evaluated a hand cream that was specially formulated for highly stressed skin with regard to its capability to reduce dry, rough, and scaly skin. The objective of this study was to conduct a controlled use test of a barrier repair cream containing pseudo-ceramide and demonstrate its efficacy for hairdressers with dry, sensitive hands and/or occupational skin disorders. A total of 30 hairdressers (29 females and 1 male, aged 20 - 67) participated in the study. All subjects suffered from dry hands. Subjects applied the test cream on their hands for 28 days (four weeks). For each subject, the skin surface topography of the hands was measured by the Surface Evaluation of Living Skin (SELS) system at day 14 (week 2) and day 28 (week 4). Dryness, scaling, cracking, redness, and itchiness were evaluated and graded by experts at week 2 and week 4, and then compared to baselines. All 30 subjects completed the study. A comparison of the changes from baseline to endpoint revealed a statistically significant reduction in skin roughness, scaling, and volume measured according to SELS. These data were confirmed by photographic documentation. The results were further supported by the expert evaluation. For the symptoms dryness and scaling, improvement could be observed in almost all regions of the hands. In addition, according to subjective assessments of overall hand skin condition and the hand cream, subjects reported clear improvement over time (p value below 0.001) and good efficacy of the product. In this study, the test hand cream showed excellent skin compatibility. Therefore, the hand cream may be effective for hairdressers with dry, sensitive hands and/or occupational skin disorders.
文摘The epidermis, and in particular its outermost layer, the stratum corneum, contributes much of the barrier function of the skin and is a readily visible representation of skin health. Maintaining the health of the skin barrier has arguably become more important than ever in the modern world, in which a large majority of people are exposed to environmental insults. These external factors can damage the integrity of the skin barrier and prematurely age the skin. Therefore, it has become increasingly important to maintain and protect the stratum corneum. Here, we briefly review the complex, multilayered structure of the skin and relate it to clinically translatable function, with an emphasis on the stratum corneum. In the context of epidermal structure and function, the formulation and clinical data for Phelityl® Reviving Cream will be reviewed. Phelityl Reviving Cream was shown to be associated with improvements in both immediate- and long-term parameters, including a significant positive effect on the skin barrier and immediate and long-lasting hydration.
文摘目的:探讨薇诺娜屏障特护霜对光动力治疗痤疮后炎症皮损的修复作用。方法:选取2020年10月-2021年2月笔者医院收治的76例痤疮患者,采用随机数字表法分为对照组和观察组,每组38例。对照组采用光动力治疗后外用创福康敷料,观察组在对照组治疗基础上予以薇诺娜屏障特护霜涂抹,两组均治疗3周,比较两组治疗效果、炎症反应症状消退时间以及治疗前后面部皮肤屏障功能。结果:观察组治疗有效率89.47%,对照组为86.84%,两组比较差异无统计学意义(P>0.05);观察组红肿、灼热、疼痛、干燥脱屑等炎症反应症状消退时间均短于对照组,差异有统计学意义(P<0.05);与治疗前比较,两组治疗后经皮水分丢失量(Transepidermal water loss,TEWL)均下降,且观察组低于对照组,差异有统计学意义(P<0.05);角质层含水量(The water content of the stratum corneum,WCSC)值均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。结论:对于光动力治疗痤疮后炎性皮损,在常规应用创福康胶原敷料的基础上外用薇诺娜屏障特护霜治疗可促进患者炎症反应症状的消退,更有利于面部炎性皮损的修复及皮肤屏障功能的改善,疗效确切。
