Objective:To explore the therapeutic effect of Dingchuan Decoction combined with omazumab on acute attack of bronchial asthma.Methods:From January 2020 to November 2021,90 patients with acute asthma were treated in ou...Objective:To explore the therapeutic effect of Dingchuan Decoction combined with omazumab on acute attack of bronchial asthma.Methods:From January 2020 to November 2021,90 patients with acute asthma were treated in our hospital,which belonged to heat asthma syndrome according to TCM syndrome differentiation in our hospital.They were divided into control group and observation group with 45 cases in each group.The control group was treated with omazumab,while the observation group was treated with omazumab combined with Dingchuan Decoction.The changes of lung function,exhaled nitric oxide(FeNO),blood gas indexes and hematological indexes were observed before and after treatment,and the adverse reactions and asthma recurrence within 3 months were observed.At the same time,animal experiments were carried out to verify the curative effect of Dingchuan.Results:After treatment,the total effective rate,FeNO,pulmonary function,partial pressure of blood oxygen(PaO_(2)),partial pressure of carbon dioxide(PaCO_(2)),interleukin-6(IL-6),interleukin-5(IL-5),immunoglobulin E(IgE)and asthma recurrence in 3 months in the observation group were better than those in the control group;There was no significant difference in pulse oxygen saturation(SaO_(2))and the incidence of adverse reactions between the two groups.Animal experiments show that Dingchuan Decoction can effectively improve lung inflammation.Conclusion:The combination of Dingchua Decoction and omazumab has a good curative effect in the treatment of acute attack of bronchial asthma,which can effectively improve the lung function and blood gas index of patients,reduce the levels of inflammatory factors and IgE,and has no obvious increase in adverse reactions,and effectively control the recurrence of asthma within 3 months.It can be used as an auxiliary maintenance treatment for patients with mild and moderate acute attack and clinical remission of asthma,thus reducing the utilization rate of hormones and having high application value.展开更多
Objective: to study the possible problems and risks in nursing management of patients with acute attack of bronchial asthma complicated with acute upper respiratory tract infection. Methods: 80 patients with acute att...Objective: to study the possible problems and risks in nursing management of patients with acute attack of bronchial asthma complicated with acute upper respiratory tract infection. Methods: 80 patients with acute attack of bronchial asthma complicated with acute upper respiratory tract infection treated in our hospital from February 2020 to February 2021 were randomly divided into study group (nursing risk management) and control group (routine nursing), with 40 cases in each group. After nursing, the nursing effects were compared. Results: the incidence of nursing adverse events in the control group was significantly higher than that in the study group (P < 0.05), and its treatment compliance, nursing satisfaction and nursing quality were significantly lower than those in the control group (P < 0.05). Conclusion: in the actual clinical treatment of patients with acute attack of bronchial asthma complicated with acute upper respiratory tract infection, in order to better improve the nursing effect and reduce the incidence of nursing adverse events, the majority of medical institutions need to take nursing risk management as the starting point, strengthen nursing risk management, eliminate the occurrence of nursing adverse events, and fundamentally promote the improvement of clinical nursing quality.展开更多
OBJECTIVE: To observe the effects of Suhuang Zhike Capsules on lung function and peripheral blood eosinophil count (EOS) and exhaled nitric oxide (eNO) in patients with acute asthma attack.METHODS: A total of 80 patie...OBJECTIVE: To observe the effects of Suhuang Zhike Capsules on lung function and peripheral blood eosinophil count (EOS) and exhaled nitric oxide (eNO) in patients with acute asthma attack.METHODS: A total of 80 patients with acute exacerbation of bronchial asthma admitted to Huai'an Cancer Hospital from January 2017 to January 2018 were randomly divided into an observation group and a control group,with 40 cases in each group.The control group was given conventional treatment with western medicine,and the observation group was given Suhuang Zhike Capsules on the basis of the treatment method of the control group.After 1 week of treatment,the improvement of individual symptoms (cough,wheezing,wheezing rale),lung function [1 second forced expiratory volume (FEV1),forced expiratory volume occupational capacity of vital capacity (FVC) in 1 second and peak expiratory flow (PEF)] and peripheral blood EOS and eNO levels and efficacy before and after the treatment were observed and assessed.RESULTS: The total effective rate of the observation group was 92.5%,which was significantly higher than the total effective rate of the control group (75.0%)(P < 0.05).The cough,wheezing and wheezing scores of the 2 groups were significantly decreased after treatment (P < 0.05).The scores of the above symptoms were significantly lower in the observation group than in the control group (P < 0.05).The FEV1,FVC and PEF were significantly increased after treatment (P < 0.05),and the above lung functions in the observation group were significantly higher than the control group (all P < 0.05).The EOS and eNO levels in the peripheral blood of the 2 groups were significantly decreased after treatment (P < 0.05),and the EOS and eNO levels in the peripheral blood in the observation group were significantly lower than those in the control group (P < 0.05).CONCLUSION: Suhuang Zhike Capsules can reduce the levels of EOS and eNO in peripheral blood of patients with acute asthma attack,improve the lung function of patients,relieve the clinical symptoms and improve the prognosis.展开更多
Objectives: This study was designed to determine the effects of air pollutants on emergency admissions for asthma, and to forecast the disease burden in Shiraz, Iran. Methods: The average daily concentrations of fine ...Objectives: This study was designed to determine the effects of air pollutants on emergency admissions for asthma, and to forecast the disease burden in Shiraz, Iran. Methods: The average daily concentrations of fine particles (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO) and ozone (O3) were calculated from data reported by two air quality monitoring stations in Shiraz from the beginning of 2007 to mid-2012. Results: The numbers of patients admitted with asthma attack during this period were collected from four main university-affiliated hospitals. Admissions correlated strongly with the levels of PM10, SO2, CO and O3 during warm seasons (P<0.001), and with NO2 level during cold seasons (P<0.001). We forecast increasing trends in air pollutants and patient admissions in the year 2015. Conclusion: Our findings are further evidence of the effects of air pollutants on asthma exacerbations.展开更多
目的探讨自拟温肺化痰汤联合布地奈德治疗急性支气管哮喘(bronchial asthma,BA)的疗效。方法选择2023年2月—2024年3月该院收治的84例急性BA患者为研究对象,按照随机数字表法分为对照组与治疗组,每组42例。对照组在常规治疗基础上联合...目的探讨自拟温肺化痰汤联合布地奈德治疗急性支气管哮喘(bronchial asthma,BA)的疗效。方法选择2023年2月—2024年3月该院收治的84例急性BA患者为研究对象,按照随机数字表法分为对照组与治疗组,每组42例。对照组在常规治疗基础上联合布地奈德治疗,治疗组在对照组基础上联合自拟温肺化痰汤治疗。比较两组治疗2周后临床疗效、中医证候积分、哮喘控制测试(asthma control test,ACT)评分、肺功能、C反应蛋白、嗜酸性粒细胞水平。结果治疗2周后,治疗组总有效率较对照组高(P<0.05)。治疗2周后,两组中医证候积分、C反应蛋白及嗜酸性粒细胞水平均降低,治疗组以上指标较对照组低(P<0.05);两组肺功能指标,ACT评分均增加,治疗组肺功能指标、ACT评分较对照组高(P<0.05)。结论自拟温肺化痰汤联合布地奈德治疗急性BA的短期效果良好,可提高疗效,在减轻患者症状,促进肺功能和炎症反应方面更具优势,值得推广。展开更多
文摘Objective:To explore the therapeutic effect of Dingchuan Decoction combined with omazumab on acute attack of bronchial asthma.Methods:From January 2020 to November 2021,90 patients with acute asthma were treated in our hospital,which belonged to heat asthma syndrome according to TCM syndrome differentiation in our hospital.They were divided into control group and observation group with 45 cases in each group.The control group was treated with omazumab,while the observation group was treated with omazumab combined with Dingchuan Decoction.The changes of lung function,exhaled nitric oxide(FeNO),blood gas indexes and hematological indexes were observed before and after treatment,and the adverse reactions and asthma recurrence within 3 months were observed.At the same time,animal experiments were carried out to verify the curative effect of Dingchuan.Results:After treatment,the total effective rate,FeNO,pulmonary function,partial pressure of blood oxygen(PaO_(2)),partial pressure of carbon dioxide(PaCO_(2)),interleukin-6(IL-6),interleukin-5(IL-5),immunoglobulin E(IgE)and asthma recurrence in 3 months in the observation group were better than those in the control group;There was no significant difference in pulse oxygen saturation(SaO_(2))and the incidence of adverse reactions between the two groups.Animal experiments show that Dingchuan Decoction can effectively improve lung inflammation.Conclusion:The combination of Dingchua Decoction and omazumab has a good curative effect in the treatment of acute attack of bronchial asthma,which can effectively improve the lung function and blood gas index of patients,reduce the levels of inflammatory factors and IgE,and has no obvious increase in adverse reactions,and effectively control the recurrence of asthma within 3 months.It can be used as an auxiliary maintenance treatment for patients with mild and moderate acute attack and clinical remission of asthma,thus reducing the utilization rate of hormones and having high application value.
文摘Objective: to study the possible problems and risks in nursing management of patients with acute attack of bronchial asthma complicated with acute upper respiratory tract infection. Methods: 80 patients with acute attack of bronchial asthma complicated with acute upper respiratory tract infection treated in our hospital from February 2020 to February 2021 were randomly divided into study group (nursing risk management) and control group (routine nursing), with 40 cases in each group. After nursing, the nursing effects were compared. Results: the incidence of nursing adverse events in the control group was significantly higher than that in the study group (P < 0.05), and its treatment compliance, nursing satisfaction and nursing quality were significantly lower than those in the control group (P < 0.05). Conclusion: in the actual clinical treatment of patients with acute attack of bronchial asthma complicated with acute upper respiratory tract infection, in order to better improve the nursing effect and reduce the incidence of nursing adverse events, the majority of medical institutions need to take nursing risk management as the starting point, strengthen nursing risk management, eliminate the occurrence of nursing adverse events, and fundamentally promote the improvement of clinical nursing quality.
文摘OBJECTIVE: To observe the effects of Suhuang Zhike Capsules on lung function and peripheral blood eosinophil count (EOS) and exhaled nitric oxide (eNO) in patients with acute asthma attack.METHODS: A total of 80 patients with acute exacerbation of bronchial asthma admitted to Huai'an Cancer Hospital from January 2017 to January 2018 were randomly divided into an observation group and a control group,with 40 cases in each group.The control group was given conventional treatment with western medicine,and the observation group was given Suhuang Zhike Capsules on the basis of the treatment method of the control group.After 1 week of treatment,the improvement of individual symptoms (cough,wheezing,wheezing rale),lung function [1 second forced expiratory volume (FEV1),forced expiratory volume occupational capacity of vital capacity (FVC) in 1 second and peak expiratory flow (PEF)] and peripheral blood EOS and eNO levels and efficacy before and after the treatment were observed and assessed.RESULTS: The total effective rate of the observation group was 92.5%,which was significantly higher than the total effective rate of the control group (75.0%)(P < 0.05).The cough,wheezing and wheezing scores of the 2 groups were significantly decreased after treatment (P < 0.05).The scores of the above symptoms were significantly lower in the observation group than in the control group (P < 0.05).The FEV1,FVC and PEF were significantly increased after treatment (P < 0.05),and the above lung functions in the observation group were significantly higher than the control group (all P < 0.05).The EOS and eNO levels in the peripheral blood of the 2 groups were significantly decreased after treatment (P < 0.05),and the EOS and eNO levels in the peripheral blood in the observation group were significantly lower than those in the control group (P < 0.05).CONCLUSION: Suhuang Zhike Capsules can reduce the levels of EOS and eNO in peripheral blood of patients with acute asthma attack,improve the lung function of patients,relieve the clinical symptoms and improve the prognosis.
文摘Objectives: This study was designed to determine the effects of air pollutants on emergency admissions for asthma, and to forecast the disease burden in Shiraz, Iran. Methods: The average daily concentrations of fine particles (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO) and ozone (O3) were calculated from data reported by two air quality monitoring stations in Shiraz from the beginning of 2007 to mid-2012. Results: The numbers of patients admitted with asthma attack during this period were collected from four main university-affiliated hospitals. Admissions correlated strongly with the levels of PM10, SO2, CO and O3 during warm seasons (P<0.001), and with NO2 level during cold seasons (P<0.001). We forecast increasing trends in air pollutants and patient admissions in the year 2015. Conclusion: Our findings are further evidence of the effects of air pollutants on asthma exacerbations.
文摘目的探讨自拟温肺化痰汤联合布地奈德治疗急性支气管哮喘(bronchial asthma,BA)的疗效。方法选择2023年2月—2024年3月该院收治的84例急性BA患者为研究对象,按照随机数字表法分为对照组与治疗组,每组42例。对照组在常规治疗基础上联合布地奈德治疗,治疗组在对照组基础上联合自拟温肺化痰汤治疗。比较两组治疗2周后临床疗效、中医证候积分、哮喘控制测试(asthma control test,ACT)评分、肺功能、C反应蛋白、嗜酸性粒细胞水平。结果治疗2周后,治疗组总有效率较对照组高(P<0.05)。治疗2周后,两组中医证候积分、C反应蛋白及嗜酸性粒细胞水平均降低,治疗组以上指标较对照组低(P<0.05);两组肺功能指标,ACT评分均增加,治疗组肺功能指标、ACT评分较对照组高(P<0.05)。结论自拟温肺化痰汤联合布地奈德治疗急性BA的短期效果良好,可提高疗效,在减轻患者症状,促进肺功能和炎症反应方面更具优势,值得推广。
