River ethics,a significant advancement inspired by Chinese President XI Jinping's ecological civilization thought,embodies the philosophical essence of river governance and represents a legacy of innovation by gen...River ethics,a significant advancement inspired by Chinese President XI Jinping's ecological civilization thought,embodies the philosophical essence of river governance and represents a legacy of innovation by generations of water resources professionals.Rooted in river ecology,it offers a framework for advancing modern water governance systems and capabilities.This paper examines eight dimensions of river ethics to provide actionable recommendations:enhancing knowledge systems on water,rivers,and lakes;addressing critical challenges in water governance to strengthen the foundational role of water authorities in ensuring water security,resource management,ecological sustainability and environmental protection;optimizing water project planning to mitigate ecological impacts;ensuring high standards in the lifecycle management of water projects;refining water diversion strategies for precise scheduling;utilizing ecosystem complexity for river and lake restoration;implementing tiered management of water-related disasters;and driving reforms to modernize water governance systems and mechanisms.展开更多
Large-volume presses(LVPs)are widely utilized in diverse research fields—including high-pressure physics,chemistry,materials science,and Earth and planetary sciences—to investigate the physical and chemical properti...Large-volume presses(LVPs)are widely utilized in diverse research fields—including high-pressure physics,chemistry,materials science,and Earth and planetary sciences—to investigate the physical and chemical properties of materials under extreme high-pressure and hightemperature conditions.A prerequisite for achieving reproducible property measurements is the determination and control of pressure within experimental setups.However,the lack of precise pressure calibration in LVPs hinders the broader application of such devices in ultrahigh-pressure studies.This study employs a suite of standard phase transition-based pressure markers—comprising metallic conductors,semiconductors,and minerals—through both in situ and ex situ identification approaches,to establish pressure calibration curves ranging from 0.4 to>30 GPa for various types of LVP installed at the Center for High Pressure Science and Technology Advanced Research(HPSTAR),Beijing,including piston–cylinder,cubic,and multi-anvil presses.The results provide a unified and traceable pressure reference for highpressure experiments conducted at HPSTAR,while also offering technical guidance and calibration standards for other researchers utilizing similar LVP systems,thereby enabling more consistent comparison between different laboratories.This work facilitates the advancement of LVP research toward broader applications in higher-pressure regimes.展开更多
Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bac...Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.展开更多
Understanding the functional effects of genetic variants is crucial in modern genomics and genetics. Transcription factor binding sites （TFBSs） are one of the most important cis-regulatory elements. While multiple t...Understanding the functional effects of genetic variants is crucial in modern genomics and genetics. Transcription factor binding sites （TFBSs） are one of the most important cis-regulatory elements. While multiple tools have been developed to assess functional effects of genetic variants at TFBSs, they usually assume that each variant works in isolation and neglect the potential ＂interference＂ among multiple variants within the same TFBS. In this study, we presented COPE-TFBS （Context-Oriented Predictor for variant Effect on Transcription Factor Binding Site）, a novel method that considers sequence context to accurately predict variant effects on TFBSs. We systematically re-analyzed the sequencing data from both the 1000 Genomes Project and the Genotype-Tissue Expression （GTEx） Project via COPE-TFBS, and identified numbers of novel TFBSs, transformed TFBSs and discordantly annotated TFBSs resulting from multiple variants, further highlighting the necessity of sequence context in accurately annotating genetic variants.展开更多
Concrete action on diversity and inclusion(D&I)is critical to companies’value creation and brand.Companies that intentionally fail to attract and retain a diverse talent pool will struggle to innovate,compete,and...Concrete action on diversity and inclusion(D&I)is critical to companies’value creation and brand.Companies that intentionally fail to attract and retain a diverse talent pool will struggle to innovate,compete,and prosper.The advantages of a diverse and inclusive workplace include the reduction of homogenous thinking and an increase in novel ideas and perspectives due to the wealth of talent from diverse backgrounds.Previous studies have focused on the benefits of corporate D&I from a corporate perspective;however,there is scant research on the impact of corporate D&I from employees’perspectives.Resultingly,this study,through an online questionnaire,proposes to examine the impact of employer brand D&I on potential employees in online recruitment channels from the perspective of potential employees.The study results indicate that most Chinese companies still exhibit low levels of D&I during recruitment.This study also included an empirical analysis of 267 valid samples,which showed that:(1)the D&I of employer brand perceptions positively impact job search intentions,behaviour,and decision making.(2)Companies’D&I has the most significant influence on job seekers’decision making,followed by behavioural influence and cognitive influence.(3)The type of job seeker plays a moderating role in the relationship between employer brand perception and job search intention,behaviour,and decision making.(4)Online recruitment’s increasing popularity amplifies employer branding’s effect.Based on the findings,this study suggests how companies can use D&I branding strategies to attract quality talent and increase job seekers’job search intentions.展开更多
研究旨在通过Meta分析评估植物多糖对羊生长性能的影响。检索2000年1月至2023年12月在中国知网、维普、万方、Web of Science和PubMed数据库中收录的关于植物多糖对羊生长性能影响的相关文章。筛选出26篇随机对照试验文章,重点研究植物...研究旨在通过Meta分析评估植物多糖对羊生长性能的影响。检索2000年1月至2023年12月在中国知网、维普、万方、Web of Science和PubMed数据库中收录的关于植物多糖对羊生长性能影响的相关文章。筛选出26篇随机对照试验文章,重点研究植物多糖对羊生长性能相关指标的Meta分析。结果显示,在饲粮中添加植物多糖能够显著提升羊的平均日增重(ADG)和平均日采食量(ADFI)(P<0.05),显著降低料重比(F/G)(P<0.05)。亚组分析结果显示,饲喂时长和植物多糖添加量均显著影响羊的ADG和F/G(P<0.05);当植物多糖添加量≤1 g/kg时,可以显著提高羊的ADFI(P<0.05),而当植物多糖添加量超过1 g/kg时,对羊的ADFI无显著差异(P>0.05)。研究表明,在饲粮中添加植物多糖对羊的生长性能具有明显的改善作用。展开更多
研究旨在全面分析近30年国际草食家畜智慧养殖相关研究发展现状和前沿热点,并提供可视化数据支撑。研究以Web of Science (WOS)核心数据集收录的发表于1996—2023年草食家畜智慧养殖相关文献为研究对象,应用CiteSpace (6.3.R1)对文献发...研究旨在全面分析近30年国际草食家畜智慧养殖相关研究发展现状和前沿热点,并提供可视化数据支撑。研究以Web of Science (WOS)核心数据集收录的发表于1996—2023年草食家畜智慧养殖相关文献为研究对象,应用CiteSpace (6.3.R1)对文献发表数量随年度变化趋势,以及国家、研究机构、期刊、关键词被引量进行共现分析、聚类分析、突现分析和可视化表达。结果显示:共获得草食家畜智慧化养殖相关英文文献276篇。近30年该研究领域文献发表数量整体呈上升趋势;研究机构主要以印度农业研究理事会、西班牙最高科研理事会和中国农业大学等为代表;国际主流学术期刊以Animal Feed Science and Technology、Journal of Animal Science和Journal of Dairy Science等为代表。草食家畜智慧畜牧业的主要研究方向为精准畜牧业、大数据、人工智能、计算机建模和智慧化管理等方面。研究表明,进一步加强畜牧智能装备研发,制造畜牧专用人工智能芯片,打造立体智慧畜牧云平台是目前和今后该领域的热点研究方向。展开更多
基金Three Gorges Follow-up Work Fund,Grant/Award Number:WE0161A042024National Key Research Program of China,Grant/Award Number:2024YFC3210900。
文摘River ethics,a significant advancement inspired by Chinese President XI Jinping's ecological civilization thought,embodies the philosophical essence of river governance and represents a legacy of innovation by generations of water resources professionals.Rooted in river ecology,it offers a framework for advancing modern water governance systems and capabilities.This paper examines eight dimensions of river ethics to provide actionable recommendations:enhancing knowledge systems on water,rivers,and lakes;addressing critical challenges in water governance to strengthen the foundational role of water authorities in ensuring water security,resource management,ecological sustainability and environmental protection;optimizing water project planning to mitigate ecological impacts;ensuring high standards in the lifecycle management of water projects;refining water diversion strategies for precise scheduling;utilizing ecosystem complexity for river and lake restoration;implementing tiered management of water-related disasters;and driving reforms to modernize water governance systems and mechanisms.
基金supported by the National Science Foundation of China(Grant Nos.U1530402 and U1930401).
文摘Large-volume presses(LVPs)are widely utilized in diverse research fields—including high-pressure physics,chemistry,materials science,and Earth and planetary sciences—to investigate the physical and chemical properties of materials under extreme high-pressure and hightemperature conditions.A prerequisite for achieving reproducible property measurements is the determination and control of pressure within experimental setups.However,the lack of precise pressure calibration in LVPs hinders the broader application of such devices in ultrahigh-pressure studies.This study employs a suite of standard phase transition-based pressure markers—comprising metallic conductors,semiconductors,and minerals—through both in situ and ex situ identification approaches,to establish pressure calibration curves ranging from 0.4 to>30 GPa for various types of LVP installed at the Center for High Pressure Science and Technology Advanced Research(HPSTAR),Beijing,including piston–cylinder,cubic,and multi-anvil presses.The results provide a unified and traceable pressure reference for highpressure experiments conducted at HPSTAR,while also offering technical guidance and calibration standards for other researchers utilizing similar LVP systems,thereby enabling more consistent comparison between different laboratories.This work facilitates the advancement of LVP research toward broader applications in higher-pressure regimes.
基金financially supported by the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2022WNLOKF009)the National Natural Science Foundation of China(No.62475216)+2 种基金the Key Research and Development Program of Shaanxi(No.2024GH-ZDXM-37)the Fujian Provincial Natural Science Foundation of China(No.2024J01060)the Startup Program of XMU,and the Fundamental Research Funds for the Central Universities.
文摘Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.
基金supported by funds from the National Key R&D Program of China (2016YFC0901603)the China 863 Program (2015AA020108)+1 种基金the State Key Laboratory of Protein and Plant Gene Researchsupported in part by the National Program for Support of Top-notch Young Professionals
文摘Understanding the functional effects of genetic variants is crucial in modern genomics and genetics. Transcription factor binding sites （TFBSs） are one of the most important cis-regulatory elements. While multiple tools have been developed to assess functional effects of genetic variants at TFBSs, they usually assume that each variant works in isolation and neglect the potential ＂interference＂ among multiple variants within the same TFBS. In this study, we presented COPE-TFBS （Context-Oriented Predictor for variant Effect on Transcription Factor Binding Site）, a novel method that considers sequence context to accurately predict variant effects on TFBSs. We systematically re-analyzed the sequencing data from both the 1000 Genomes Project and the Genotype-Tissue Expression （GTEx） Project via COPE-TFBS, and identified numbers of novel TFBSs, transformed TFBSs and discordantly annotated TFBSs resulting from multiple variants, further highlighting the necessity of sequence context in accurately annotating genetic variants.
文摘Concrete action on diversity and inclusion(D&I)is critical to companies’value creation and brand.Companies that intentionally fail to attract and retain a diverse talent pool will struggle to innovate,compete,and prosper.The advantages of a diverse and inclusive workplace include the reduction of homogenous thinking and an increase in novel ideas and perspectives due to the wealth of talent from diverse backgrounds.Previous studies have focused on the benefits of corporate D&I from a corporate perspective;however,there is scant research on the impact of corporate D&I from employees’perspectives.Resultingly,this study,through an online questionnaire,proposes to examine the impact of employer brand D&I on potential employees in online recruitment channels from the perspective of potential employees.The study results indicate that most Chinese companies still exhibit low levels of D&I during recruitment.This study also included an empirical analysis of 267 valid samples,which showed that:(1)the D&I of employer brand perceptions positively impact job search intentions,behaviour,and decision making.(2)Companies’D&I has the most significant influence on job seekers’decision making,followed by behavioural influence and cognitive influence.(3)The type of job seeker plays a moderating role in the relationship between employer brand perception and job search intention,behaviour,and decision making.(4)Online recruitment’s increasing popularity amplifies employer branding’s effect.Based on the findings,this study suggests how companies can use D&I branding strategies to attract quality talent and increase job seekers’job search intentions.
文摘研究旨在通过Meta分析评估植物多糖对羊生长性能的影响。检索2000年1月至2023年12月在中国知网、维普、万方、Web of Science和PubMed数据库中收录的关于植物多糖对羊生长性能影响的相关文章。筛选出26篇随机对照试验文章,重点研究植物多糖对羊生长性能相关指标的Meta分析。结果显示,在饲粮中添加植物多糖能够显著提升羊的平均日增重(ADG)和平均日采食量(ADFI)(P<0.05),显著降低料重比(F/G)(P<0.05)。亚组分析结果显示,饲喂时长和植物多糖添加量均显著影响羊的ADG和F/G(P<0.05);当植物多糖添加量≤1 g/kg时,可以显著提高羊的ADFI(P<0.05),而当植物多糖添加量超过1 g/kg时,对羊的ADFI无显著差异(P>0.05)。研究表明,在饲粮中添加植物多糖对羊的生长性能具有明显的改善作用。
文摘研究旨在全面分析近30年国际草食家畜智慧养殖相关研究发展现状和前沿热点,并提供可视化数据支撑。研究以Web of Science (WOS)核心数据集收录的发表于1996—2023年草食家畜智慧养殖相关文献为研究对象,应用CiteSpace (6.3.R1)对文献发表数量随年度变化趋势,以及国家、研究机构、期刊、关键词被引量进行共现分析、聚类分析、突现分析和可视化表达。结果显示:共获得草食家畜智慧化养殖相关英文文献276篇。近30年该研究领域文献发表数量整体呈上升趋势;研究机构主要以印度农业研究理事会、西班牙最高科研理事会和中国农业大学等为代表;国际主流学术期刊以Animal Feed Science and Technology、Journal of Animal Science和Journal of Dairy Science等为代表。草食家畜智慧畜牧业的主要研究方向为精准畜牧业、大数据、人工智能、计算机建模和智慧化管理等方面。研究表明,进一步加强畜牧智能装备研发,制造畜牧专用人工智能芯片,打造立体智慧畜牧云平台是目前和今后该领域的热点研究方向。
