目的运用Meta分析评价能谱CT成像鉴别肺癌与炎性肿块的能力。资料与方法检索PubMed、Web of Science、Embase、中国知网和万方数据库中于2007年1月—2017年10月发表的有关能谱CT成像鉴别肺癌和炎性肿块的中、英文文献,提取相关数据,汇...目的运用Meta分析评价能谱CT成像鉴别肺癌与炎性肿块的能力。资料与方法检索PubMed、Web of Science、Embase、中国知网和万方数据库中于2007年1月—2017年10月发表的有关能谱CT成像鉴别肺癌和炎性肿块的中、英文文献,提取相关数据,汇总能谱特征参数,包括碘浓度(IC)、水浓度(WC)、标准化碘浓度(NIC)、能谱曲线斜率的标准化均数差(SMD)及其95%可信区间(CI),汇总NIC的诊断效能。结果共纳入16篇文献,总例数为1074例,其中肺癌727例,炎性病变347例。依次以IC、WC、NIC、斜率作为肺癌和炎性肿块之间的鉴别指标,肺癌的IC值[SMD=-1.44(-2.34～-0.55),P=0.002]、NIC[SMD=-0.75(-1.41～-0.09),P=0.03]及斜率[SMD=-0.89(-1.63～-0.15),P=0.02]均低于炎性病变,差异有统计学意义;WC值差异无统计学意义[SMD=0.01(-0.20～0.23),P=0.91]。单独汇总NIC的诊断敏感度、特异度分别为0.82(0.75～0.87)、0.93(0.73～0.98)。结论 IC、NIC、能谱曲线斜率作为能谱CT的特征参数可有效鉴别肺癌与炎性肿块,而NIC能较好地反映病变的血供特性,是更有效的评价指标。展开更多
The method of principal component analysis was applied to systematical research on the soil multi-media environment, including soil, surface water, ground water, waterbody sediment and agricultural crops, as well as p...The method of principal component analysis was applied to systematical research on the soil multi-media environment, including soil, surface water, ground water, waterbody sediment and agricultural crops, as well as pollution-inducing wastewater, mullock (or waste ore) and slag in the periphery of a large-sized Pb-Zn mining and smelting plant in a karst area of Guangxi Zhuang Autonomous Region. The results revealed that soils in the area studied have been heavily polluted by Cd, Zn, Pb and Hg, and the levels of these metals in the samples of agricultural crop greatly exceed the standards. The above-mentioned pollutants exist in all soil-multi-media environments. The mullock, slag, wastewater, surface water, ground water, soil, and agricultural crops constitute a composite ecological chain. Therefore, the improper disposal of mullock and slag, and the use of polluted wastewater for agricultural irrigation are the main causes of soil pollution. Heavy metals in the soil have three transition progresses: point (improved soil with slag, ground water inflow plot), linear (river transition) and non-point transition (regional pollution by slag) patterns, and the tailing yard is the most important locus for heavy metals to release into the environment.展开更多
The feasibility of gingko (Gingo Biloba) foliage as a passive bio-monitor for organochlorine pesticides in air was explored. The accumulation patterns of hexachlorocyclohexanes (HCHs), dichlorodiphenyl- trichloroethan...The feasibility of gingko (Gingo Biloba) foliage as a passive bio-monitor for organochlorine pesticides in air was explored. The accumulation patterns of hexachlorocyclohexanes (HCHs), dichlorodiphenyl- trichloroethanes (DDTs) and hexachlorobenzene (HCB) in gingko foliage were similar; the amounts of HCHs, DDTs and HCB increased with foliage growth in spring and decreased thereafter. This accumu-lation pattern is likely related to the growing process of the gingko foliage, which was observed for the first time in our work, giving a piece of evidence for the "bud burst effect" in plants. Compared with those in pine needles in 1980's, the residual levels of HCHs and DDTs have declined obviously in Bei-jing, indicating that the ban on the production and use of organochlorine pesticides (OCPs) in our country is effective; however, the amount of HCB has increased, indicating great progress of chemical industry in Beijing. The analysis for the source of OCPs in the gingko foliage showed that the technical HCHs and DDTs were used largely in history, but were not used in recent years. A little lidane has been used and there was a new input of o,p′-DDT in recent years; dicofol usage may be the main source of o,p′-DDT. Concentrations of HCHs, DDTs and HCB in gingko foliages were similar to those in pine nee-dles in the corresponding period and there is a strong positive correlation between the OCPs concen-tration data obtained from these two kinds of trees. It presents no difference in the accumulation style between these two kinds of trees. The level of OCPs in the gingko foliage reflects the pollution status of OCP in air. The result of this work shows that the gingko foliage can be used as a bio-monitor of OCPs in air.展开更多
文摘目的运用Meta分析评价能谱CT成像鉴别肺癌与炎性肿块的能力。资料与方法检索PubMed、Web of Science、Embase、中国知网和万方数据库中于2007年1月—2017年10月发表的有关能谱CT成像鉴别肺癌和炎性肿块的中、英文文献,提取相关数据,汇总能谱特征参数,包括碘浓度(IC)、水浓度(WC)、标准化碘浓度(NIC)、能谱曲线斜率的标准化均数差(SMD)及其95%可信区间(CI),汇总NIC的诊断效能。结果共纳入16篇文献,总例数为1074例,其中肺癌727例,炎性病变347例。依次以IC、WC、NIC、斜率作为肺癌和炎性肿块之间的鉴别指标,肺癌的IC值[SMD=-1.44(-2.34～-0.55),P=0.002]、NIC[SMD=-0.75(-1.41～-0.09),P=0.03]及斜率[SMD=-0.89(-1.63～-0.15),P=0.02]均低于炎性病变,差异有统计学意义;WC值差异无统计学意义[SMD=0.01(-0.20～0.23),P=0.91]。单独汇总NIC的诊断敏感度、特异度分别为0.82(0.75～0.87)、0.93(0.73～0.98)。结论 IC、NIC、能谱曲线斜率作为能谱CT的特征参数可有效鉴别肺癌与炎性肿块,而NIC能较好地反映病变的血供特性,是更有效的评价指标。
基金support by Guangxi Scientific and Technological Brainstorm Project (Guikegong 0779011)
文摘The method of principal component analysis was applied to systematical research on the soil multi-media environment, including soil, surface water, ground water, waterbody sediment and agricultural crops, as well as pollution-inducing wastewater, mullock (or waste ore) and slag in the periphery of a large-sized Pb-Zn mining and smelting plant in a karst area of Guangxi Zhuang Autonomous Region. The results revealed that soils in the area studied have been heavily polluted by Cd, Zn, Pb and Hg, and the levels of these metals in the samples of agricultural crop greatly exceed the standards. The above-mentioned pollutants exist in all soil-multi-media environments. The mullock, slag, wastewater, surface water, ground water, soil, and agricultural crops constitute a composite ecological chain. Therefore, the improper disposal of mullock and slag, and the use of polluted wastewater for agricultural irrigation are the main causes of soil pollution. Heavy metals in the soil have three transition progresses: point (improved soil with slag, ground water inflow plot), linear (river transition) and non-point transition (regional pollution by slag) patterns, and the tailing yard is the most important locus for heavy metals to release into the environment.
基金the State Key Development Program for Basic Research of China (Grant No. 2003CB415003)
文摘The feasibility of gingko (Gingo Biloba) foliage as a passive bio-monitor for organochlorine pesticides in air was explored. The accumulation patterns of hexachlorocyclohexanes (HCHs), dichlorodiphenyl- trichloroethanes (DDTs) and hexachlorobenzene (HCB) in gingko foliage were similar; the amounts of HCHs, DDTs and HCB increased with foliage growth in spring and decreased thereafter. This accumu-lation pattern is likely related to the growing process of the gingko foliage, which was observed for the first time in our work, giving a piece of evidence for the "bud burst effect" in plants. Compared with those in pine needles in 1980's, the residual levels of HCHs and DDTs have declined obviously in Bei-jing, indicating that the ban on the production and use of organochlorine pesticides (OCPs) in our country is effective; however, the amount of HCB has increased, indicating great progress of chemical industry in Beijing. The analysis for the source of OCPs in the gingko foliage showed that the technical HCHs and DDTs were used largely in history, but were not used in recent years. A little lidane has been used and there was a new input of o,p′-DDT in recent years; dicofol usage may be the main source of o,p′-DDT. Concentrations of HCHs, DDTs and HCB in gingko foliages were similar to those in pine nee-dles in the corresponding period and there is a strong positive correlation between the OCPs concen-tration data obtained from these two kinds of trees. It presents no difference in the accumulation style between these two kinds of trees. The level of OCPs in the gingko foliage reflects the pollution status of OCP in air. The result of this work shows that the gingko foliage can be used as a bio-monitor of OCPs in air.
