摘要
脂质体作为药物递送的良好载体,其制备工艺距今约有半个多世纪的研究历史。实验室层面的脂质体制备技术已趋于成熟,现阶段的研究主要着眼于脂质体的制备由实验室至工业生产的过渡,若攻克此壁垒,将迎来脂质体药物上市的春天。本文将从脂质体制备技术的传统和非传统两个方面进行介绍,总结每个大类下的研究进展,为实验中涉及脂质体制备的科研工作者提供帮助。
As a good carrier for drug delivery, liposomes have a research history of more than half a century in the preparation process. The liposome preparation technology at the laboratory level has become mature, and the current research mainly focuses on the transition of liposome preparation from la-boratory to industrial production. If this barrier is overcome, it will usher in the spring of liposome drug listing. This article will introduce the traditional and non-traditional aspects of liposome preparation technology, summarize the research progress under each category, and provide help for scientific researchers involved in the preparation of liposomes.
出处
《药物化学》
2022年第2期144-152,共9页
Hans Journal of Medicinal Chemistry
