摘要
目的 探讨重建阴囊对睾丸生精功能的影响。方法 对 2例阴囊皮肤撕脱伤后采用髂腹股沟皮瓣重建阴囊进行长达 4年的随访 ,并分别作了精液常规检查、睾丸活检、性功能及性激素水平测定。为排除临床上可能存在的睾丸及精索挫伤造成的生精功能障碍 ,以育龄家兔为实验动物 ,手术剥脱其阴囊 ,采用下腹部皮瓣重建 ,观察其睾丸的生精功能情况。结果 临床病例随访显示 ,在重建阴囊早期 ,对睾丸的生精功能影响不大 ,但随着时间延长 ,精子数及活动率明显降低。皮瓣重建家兔阴囊 2个月后 ,其睾丸的生精功能明显下降 ,与育龄雌兔交配 ,无生育能力。结论 对阴囊皮肤撕脱伤采用较厚的皮瓣重建应慎重。
Objective To explore the effect of scrotum reconstruction with a skin flap on spermatogenesis. Methods Two patients who underwent scrotum reconstruction with the skin flap were followed up for four years. Their sperm quality,sex function,sexual hormone,and testis biopsy were examined. To exclude the influential factors of testis and spermatic cord contusing,an experiment study was designed and performed in rabbits. The scrotal skin of the rabbits was stripped off and the scrotum was reconstructed with a hypogastric skin flap. Results The clinical follow-up indicated that in the early postoperative period,the reconstruction did not impede spermatogenesis,but the arrest of spermatogenesis happened with time. The experimental results showed that the sperm count of the rabbits decreased obviously and the rabbits became sterile two months after scrotum reconstruction. Conclusion The thick skin flap is not recommended for scrotum reconstruction. ;
出处
《中华整形外科杂志》
CAS
CSCD
北大核心
2004年第3期203-205,共3页
Chinese Journal of Plastic Surgery
基金
贵州省科技基金资助项目 (2 0 0 0 3 0 45 )
