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凋亡过程中真核细胞翻译启始因子与蛋白质翻译

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摘要 细胞凋亡引起细胞主动死亡,此过程中蛋白质的合成受到影响。在细胞凋亡时caspases被激活,并抑制真核细胞翻译启始因子(eIF)家族成员的活性,后者对蛋白质的表达有重要意义。研究凋亡过程中的eIF家族成员为诱导肿瘤细胞凋亡提供了新思路。
作者 陶磊 周梁
机构地区 复旦大学附属眼耳鼻喉科医院
出处 《国外医学（遗传学分册）》 2004年第3期137-139,174,共4页 Foreign Medical Sciences(Section of Genetics )
基金 上海市科技发展基金资助项目(No.014119047)
关键词 真核细胞翻译启始因子 蛋白质翻译 细胞凋亡 CASPASES 诱导 肿瘤细胞
分类号 Q75 [生物学—分子生物学]
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参考文献11

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国外医学（遗传学分册）
2004年 第3期

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