9[9]Ueda M, Kreuter J. Optmization of the preparation of loperamide-loaded poly (L- lactide) nanoparticles by high pressure emulsification- solvent evaporation [J]. J Microencapsul ,1997, 14(5) :593～595
10[10]Zambaux MF , Bonneaux F , Gref R , et al . Influence of experimental parameters on the characteristics of poly (lactic acid) nanoparticles prepared by a double emulsion method[J].J Controlled Release , 1998, 50:31～33
