摘要
目的:观察康莱特联合卡莫氟对改善晚期胃癌患者生活质量的作用。方法:采用前瞻性随机对照研究方法,入院患者随机分为治疗组43例(康莱特联合卡莫氟治疗)和对照组42例(单用卡莫氟治疗),分别观察治疗后肿瘤大小、体质量及karnofsky评分的变化。结果:收治96例晚期胃癌患者,可评价疗效85例,除在肿瘤的缩小两组间无明显差异外,其体质量增加、karnofsky评分改善方面,治疗组均优于对照组,差异有显著性意义(P<0.05)。结论:康莱特联合卡莫氟不仅能相对提高晚期胃癌的治疗效果,而且能增加体质量、改善晚期胃癌患者的生活质量。
AIM:To observe the effects of xeloda(carmofur) in the improvement of quality of life in patients with advanced carcinoma of stomach. METHODS:A prospective randomized controlled trial was conducted in 85 hospitalized patients with advanced carcinoma of stomach who were randomly divided into treatment group(treated with xeloda combined with carmofur,n=43) and control group(treated with carmofur,n=42).Then,the changes of tumor size,body mass and karnofsky scores in the two groups were observed after treatment. RESULTS:The curative effect of 85 cases could be assessed among the 96 hospitalized patients with advanced carcinoma of stomach.The increase of body mass and the improvement of karnofsky scores were more obvious in the treatment group than in the control group,showing marked significance(P < 0.05),while the reduction of tumor size had no significant difference between the two groups. CONCLUSION:Xeloda combined with carmofur can not only improve the therapeutic effects on advanced carcinoma of stomach,but also increase the body mass,improve the quality of life in the patients with advanced carcinoma of stomach.
出处
《中国临床康复》
CSCD
2004年第14期2608-2609,共2页
Chinese Journal of Clinical Rehabilitation
