摘要
了解不同时期江西地区宫颈癌患者发病年龄、临床病理特征及其它相关危险因素的变化。方法:对本院1989年1月至1989年12月(20世纪80年代组)和1999年1月至1999年12月(20世纪90年代组)收治的421例宫颈癌患者进行回顾性分析,并按10岁的间隔进行年龄分组比较。结果:两组患者的平均年龄分别为(57.6±10.70)岁和(50.5±13.0)岁(P<0.001),年龄曲线随时间推移呈明显下降趋势。两组患者的宫颈癌组织学类型和分级无显著差异。但90年代组多为较早期肿瘤,Ⅰb期占22.9%;而80年代组晚期患者多,Ⅰb期占2.4%(P<0.05)。结论:子宫颈癌患者年轻化的趋势是显而易见的,重视对宫颈癌年轻化趋势的认识,加强对年轻宫颈疾患者的普查和治疗,可望达到早诊、早治,从而降低宫颈浸润癌的发病率和死亡率。
Objective: To identify any significant change in age at diagnosis and the clinicopathological or demographic characteristics of women diagnosed with cervical cancer in Jiangxi over the past 10 years. Methods: The clinico-pathological and demographic features of 168 women with invasive cervical cancer diagnosed in 1989(group 1) were compared with that of 253 women diagnosed in 1999(group 2)in the Jiangxi Gynaecology and Obstetrics Hospital during the two periods (n=421). The age groups were stratified into 10 year intervals, age<40 years, 40-49 years,50-59 years and ≥60 years. Results: The mean age at diagnosis was 57.6±10.7 years in group 1 and 50.5±13.0 years in group 2, respectively (P<0.001). There was no significant difference between two groups in histological type and grade of cancers. However, group 2 presented significantly more earlier stage cancer cases than that of group 1, 22.9% of patients in group 2 had stage Ib disease, compared with only 2.4% in group 1 (P<0.05). The older patients in both groups had more pregnancies and births than younger patients (P<0.05). Conclusions: The age at diagnosis of invasive cervical cancer in Jiangxi is obviously tends to be young. We must emphasize the tendency of cervical cancer in young women and reinforce the cencus and therapy of young women. To prevent and diagnose cervical cancer is important to reduce the morbidity and mortality of cervical cancer.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2004年第10期547-549,共3页
Chinese Journal of Clinical Oncology
基金
国家自然科学基金资助(编号:30160090)
关键词
宫颈癌
年龄
构成比
Cervical cancer Age Composing ratio
