摘要
探讨宫颈癌年轻化的有关因素 ,临床特点和诊治问题。国内外资料显示≤35岁(或<30岁)妇女宫颈癌发病率由70年代的8 6/10万增加到80年代初的16 1/10万。中国医学科学院肿瘤医院年轻宫颈癌在全部宫颈癌中所占比例由70年代的1 22% ,80年代的1 42% ,到90年代的9 88%。宫颈癌年轻化的原因可能与性因素、病毒感染 ,尤其是人乳头瘤病毒感染(HPVI)等有关。年轻宫颈癌中腺癌比例增高 ,中、晚期占多数 ,预后较差。在诊治中强调三早 ,90年代末使用的TheThinpreppaptest(TCT)新柏氏超薄细胞检测新技术大大提高细胞学涂片质量 ,减少了细胞学的假阴性。治疗中应注重个体化 。
To investigate the factors relative to the trend of young patients with carcinoma of the cervix and its clinical characteristics,diagnosis and treatment Some researches showed the prevalance of young women (≤35 or <30 years)with cervical cancer increased from 8 6/100000 in 1970s to 16 1/100000 in 1980s The percentage of young patients in all cervical cancer was 1 22% in 1970s and 1 42% in 1980s and 9 88% in 1990s in Cancer Hospital CAMS Sexual factors,viral infection,especially human papillomavirals infection (HPVI) etc may be main causes The percentage of adnocarcinoma of the cervix enhanced up to 18 1%～36 9%,the more advanced cases were predominating,prognosis of young patients were poorer Early finding,diagnosis and treatment are very important At present,using the Thinprep pap test (TCT),a new cytological technique,improved the quality of pap smear and decreased false negative rate In management of young patient,tailor treatment,reserving fertility and physiological function must be emphasized
