摘要
目的 观察舒芬太尼复合罗比卡因用于子宫切除术术后硬膜外病人自控镇痛 (PCEA)效应。方法 选择 6 0例ASAⅠ～Ⅱ级于硬膜外麻醉下行腹式子宫全切术的病人 ,随机分为两组 (n=30 )。术后采用LCP模式行PCEA ,即负荷剂量 (5ml) +持续剂量 (2ml/h) +PCA剂量 (2ml/次 ) ,锁定时间 10min。A组镇痛用药为 0 2 %罗比卡因 +舒芬太尼 (0 4 μg/ml) ;B组为 0 2 %罗比卡因 +芬太尼 (4 μg/ml)。术后 4、8、12、2 0、2 4h双盲对照观察两组镇痛药用量、视觉模拟评分 (VAS)、镇静评分、运动阻滞评分以及恶心、呕吐、眩晕等不良反应发生情况。结果 A组舒芬太尼用量为 (2 6 5 0±2 80 ) μg ;B组芬太尼用量为 (2 74 30± 15 80 ) μg。两组罗比卡因用量无统计学差异。组间相同时间段内VAS、BCS及Bromage评分基本相似 (P >0 0 5 )。两组间不良反应发生率无明显差异 ,两组病人生命体征稳定。结论 以LCP模式采用舒芬太尼或芬太尼复合 0 2 %罗比卡因行PCEA 。
Objective To investigate the effect of patient controlled epidural analgesia(PCEA)with sufentanil 0.4 μg/ml combined with 0.2% ropivacaine after abdominal hysterectomy.Methods Sixty patient(ASA Ⅰ-Ⅱ)underwent elective abdominal hysterectomy were randomly divided into two groups.Group A received sufentanil 0.4 μg/ml+0.2% ropivacaine for PCEA,Group B received PCEA with fentanil 4 μg/ml+0.2% ropivacaine.PCEA included loading dose 5 ml,bolus of 2 ml with lock time 10 minutes and background 2 ml/h.The analgesia effects was evaluated by visual scales.Bruggrmann comfort scale and midified bromge score.Side effects such as nausea and vomiting were also recorded.Results Both group A and group B showed good pain relief.There were no significant diffrences in VAS scores,BCS,Bromage score between two groups.The dose of sufentanill was (26.50±2.80) μg in group A and fentanil was (247.30±15.80 μg) in group B.There were no differences in side effects between both groups.Conclusion PCEA with sufentanil or fentanil+0.2% ropivacaine was safe and effective for patient after hysterectomy.
出处
《临床麻醉学杂志》
CAS
CSCD
2004年第5期280-282,共3页
Journal of Clinical Anesthesiology
