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拓扑异构酶抑制剂的研究进展 被引量:2

Progress of studies on the inhibitors of topoisomerase
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出处 《武警医学院学报》 CAS 2004年第3期260-262,265,共4页 Acta Academiae Medicinae CPAPF
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参考文献15

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  • 2[2]Hsiang YH,liu LF.Identification of mammalian DNAtopoisomerase I as an intracellular target of the anticancer drug camptothecin J[J].Cancer Res,1988,45(7) :1722-1726.
  • 3邵荣光.新分子靶点的抗癌药物研究[J].中国肿瘤,2002,11(4):228-230. 被引量:11
  • 4宋云龙,张万年,季海涛,周有骏,朱驹,吕加国.喜树碱药效构象及分子内氢键对抗肿瘤活性的影响[J].中国药物化学杂志,2001,11(6):311-315. 被引量:2
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  • 7孙正怡,沈铿.DNA拓扑异构酶I抑制剂在卵巢癌治疗中的应用[J].中华妇产科杂志,1999,34(6):378-379. 被引量:4
  • 8[8]Hochster H,Speyer J,Wadler S,et al.Phase Ⅱ study of topotecan(TPT) 21-day infusion in platinum-treated ovarian cancer:A highly active regimen(a NYGOG study)[J].Proc Am Soc Clin Oncol,1996,15:285-287.
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二级参考文献8

共引文献17

同被引文献31

  • 1A. Kathleen McClendon. DNA topoisomerase Ⅱ[J]. genotoxicity, and cancer Mutation Research 2007, 623: 83- 97.
  • 2Lok RB. Anti-cancer Drug Design, 1987 (2)151-164.
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  • 6Redinbo MR. Novel Insights into Catalytic Mechanism from a Crystal Structure of Human Topoisomerase Ⅰ in Complex with DNA [ J ] . Biochemistry, 2000, 39 (23) : 6832-6840.
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  • 9Von-Hoff DD. Preclinical and phase Ⅰ trials of topoisomerase Ⅰ inhibitors [J]. Cancer Chemother Pharmacol, 1994, 34(Suppl): S41-S45.
  • 10Utsugi T. Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases Ⅰ and Ⅱ[J]. Jpn J Cancer Res, 1997, 88(10): 992-1002.

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