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VEGF及其受体与膀胱肿瘤关系的研究现状 被引量:1

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摘要 膀胱癌是泌尿系统最常见的恶性肿瘤 ,在泌尿系统肿瘤中发病率和由于复发、转移所致的死亡率均居首位。目前尽管有手术、化疗、免疫治疗等多种方法 ,但还没有一种办法能从根本上治疗膀胱癌。近来的研究证实 ,肿瘤发生时 ,病灶及瘤周将会发生持续的、失控的血管生成 ;恶性肿瘤的发生、发展及转移的各阶段均有赖于新生血管的形成[1 ] 。由此 ,这种以肿瘤血管为靶的治疗策略 -肿瘤血管靶向治疗引起了人们极大的兴趣并且日益受到重视。在抗血管生成治疗中 ,被广泛认为 ,阻滞肿瘤细胞分泌VEGF ,并干扰VEGF与其受体结合 ,是极具发展潜力和有广阔应用前景的一种崭新的抗癌策略。
作者 刘禄成
出处 《国外医学(泌尿系统分册)》 2004年第3期335-338,共4页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
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参考文献20

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同被引文献13

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