期刊文献+

血管内皮生长因子在乳腺癌中的研究进展

暂未订购
导出
摘要 乳腺癌是危害妇女健康的常见恶性肿瘤之一,其发病率和死亡率均呈较快的增长趋势。乳腺癌与所有实体肿瘤一样,肿瘤细胞旺盛的代谢、增殖需要充足的血液供应,肿瘤新生血管形成与肿瘤的发生、发展及预后密切相关。血管内皮生长因子(VEGF)是特异作用于血管内皮细胞、上调血管生成的重要因子,能刺激血管内皮细胞增殖、迁移和诱导血管生成。研究发现,VEGF在许多肿瘤组织中高表达。本文就VEGF在乳腺癌中的研究进展作一综述。
作者 粟连秀
出处 《医学文选》 2006年第3期537-539,共3页 Anthology of Medicine
  • 相关文献

参考文献14

二级参考文献83

  • 1Xiu-Sheng He Qi Su Zhu-Chu Chen Xiu-Tao He Zhi-Feng Long Hui Ling Liang-Run Zhang Oncology Institute,Nanhua University,Hengyang 421001,Hunan Province,ChinaOncology Institute,Center South University,Changsha 410078,Hunan Province,China Department of Gastroenterology,First People’s Hospital of Changde City,Changde 415003,Hunan Province,China.Expression,deleton and mnutation of ρ16 gene in human gastric cancer[J].World Journal of Gastroenterology,2001,7(4):515-521. 被引量:40
  • 2Mcguire WL, Clark GM. Prognostic factors and treatment decisions in axillary-node-negative breast cancer. N Engl J Med, 1992, 326:1756-1761.
  • 3Jatoi I. Management of the axilla in primary breast cancer. Surg Clin North Am, 1999,79(5):1061-1071.
  • 4Pusztai L, Lewis CE, Lorenzen J, et al. Growth Factors : Regulation of normal and neoplastic growth. J Pathol,1993,169(2):191-201.
  • 5Massague J. Receptor for the TGFβ1 family. Cell, 1992,69(6):1067-1073.
  • 6Cardillo MR, Yap E, Gstagna G. Molecular genetic analysis of TGFβ1 in breast cancer. J Exp Lin Res,1997, 16(1):57-63.
  • 7Pasche B. Role of TGFβ in cancer. J Cell physiol, 2001,186(27) : 153-168.
  • 8Ohta Y,Watanabe Y, Murakami S, et al. Vascular endothelial growth factor and lymph node metastasis in lung cancer. Br J Cancer,1997,75(6):1041-1045.
  • 9Dvorak HF, Brown LF, Detmar M, et al. Vascular permeability factor/vascula endothelial growth factor,microvascular hyper-permeability and angiogenesis. Am J Pathol, 1995, 146(6):1029-1039.
  • 10Sauter ER,Nesbit M,Watson JC,et al.Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck. Clin Cancer Res, 1999,5(4):775-778.

共引文献100

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部